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Protein Overview: PEX13

General Information:
Name(s) found: PEX13 / YLR191W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Integral peroxisomal membrane required for the translocation of peroxisomal matrix proteins, interacts with the PTS1 signal recognition factor Pex5p and the PTS2 signal recognition factor Pex7p, forms a complex with Pex14p and Pex17p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 386 amino acids

    Gene Ontology:
    Cellular Component: peroxisomal membrane [TAS]
    Biological Process: protein import into peroxisome matrix [IMPLink to PubMed article]
    protein targeting to peroxisome [IGILink to PubMed article][IPILink to PubMed article]
    peroxisome organization [TAS]
    Molecular Function: protein binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTAVPRPK PWETSASLEE PQRNAQSLSA MMTSNQQDSR PTEESNNSNS ASESAPEVLP  60
   61 RPAALNSSGT YGESNTIPGI YGNSNYGIPY DNNPYSMNSI YGNSIGRYGY GGSYYGNNYG 120
  121 SFYGGGYGAG AGYGMNNGSG LGESTKATFQ LIESLIGAVT GFAQMLESTY MATHNSFFTM 180
  181 ISVAEQFGNL KEMLGSFFGI FAIMKFLKKI LYRATKGRLG IPPKNFAESE GSKNKLIEDF 240
  241 QKFNDSGTIN SNEKATRRKI SWKPLLFFLM AVFGFPYLLN KFITKLQTSG TIRASQGNGS 300
  301 EPIDPSKLEF ARALYDFVPE NPEMEVALKK GDLMAILSKK DPLGRDSDWW KVRTKNGNIG 360
  361 YIPYNYIEII KRRKKIEHVD DETRTH

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) INP1 INP2 PEX10 PEX12 PEX13 PEX14 PEX17 PEX2 PEX21 PEX25 PEX28 PEX3 PEX30 PEX7 PEX8

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PEX13 OMA1 2 Unpublished Fields Lab Data
    View Screen PEX13 PEX19 2 Unpublished Fields Lab Data
    View Screen PEX13 PEX14 2 Unpublished Fields Lab Data
    View Screen PEX13 PEX18 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data PEX13 and PEX3 Huh WK, et al. (2003)
    View Data PEX13 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..109] MSA 1.006981 View MSA. No confident structure predictions are available.
    2 View Details [110..198] deduced N/A Confident ab initio structure predictions are available.
    3 View Details [199..302] PSI-BLAST 6.0 Growth factor receptor-bound protein 2 (GRB2)
    4 View Details [303..386] PSI-BLAST 63.39794 Bruton's tyrosine kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.55003340159545 bayes_pls_golite062009
  • protein binding
    		•  2.35325421236395 bayes_pls_golite062009
  • molecular adaptor activity
    		•  0.68555837423221 bayes_pls_golite062009
  • signal transducer activity
    		•  0.644330423191792 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.644330423191792 bayes_pls_golite062009
  • hydrolase activity
    		•  0.31081944790532 bayes_pls_golite062009
  • protein binding, bridging
    		•  0.230308623372106 bayes_pls_golite062009
  • receptor binding
    		•  0.00920732436841987 bayes_pls_golite062009
    4
    Term Confidence Notes
  • binding
    		•  2.49184519104882 bayes_pls_golite062009
  • protein binding
    		•  2.29371158534719 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.67112127425228 bayes_pls_golite062009
  • transporter activity
    		•  1.30447542854757 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.08558010881058 bayes_pls_golite062009
  • actin binding
    		•  0.75525840382431 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.566172161499832 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.325817349097199 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.00508584255499911 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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