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Protein Overview: CWC24

General Information:
Name(s) found: CWC24 / YLR323C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Essential protein, component of a complex containing Cef1p; has similarity to S. pombe Cwf24p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 259 amino acids

    Gene Ontology:
    Cellular Component: spliceosomal complex [IPILink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRKRLVNKS SSDEKNQKKR QKINFSEEKL VASDEEKGSS DLMSLAKSGN SRTLQLSHEN  60
   61 EGKLQKKGED LDKYTLTVND DSTKEDLLNF ERKELAEKAK KRRPSDDNEL VLNMSGKNKR 120
  121 LTKQINQPTN IRTTVLMDFQ PDVCKDYKQT GYCGYGDSCK FLHSRDDFKT GWKLNQEWNA 180
  181 DKEDSKAVTL DLEKIPFKCT LCKEDYKSPV VTNCGHYFCG SCFAKDMKKG TKCFICHKET 240
  241 HGSAKVASDL QKMLNKRKS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CWC24 and SPC42 Unpublished Data
    View Data CWC24 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..168] MSA 3.389986 View MSA. No confident structure predictions are available.
    2 View Details [169..259] PSI-BLAST 15.69897 V(D)J recombination activating protein 1 (RAG1), dimerization domain
    3 View Details [186..259] PSI-BLAST 15.30103 RAG1 DIMERIZATION DOMAIN

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
    		• 4.77196423114965 bayes_pls_golite062009
  • RNA binding
    		•  2.35680777511144 bayes_pls_golite062009
  • binding
    		•  2.19426901055464 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  2.17320579037083 bayes_pls_golite062009
  • ligase activity
    		•  2.11117401820312 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  2.10698039886692 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.62076236255768 bayes_pls_golite062009
  • protein binding
    		•  1.34794206219054 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  1.22312570999194 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.22180889694654 bayes_pls_golite062009
  • DNA binding
    		•  1.00346149950987 bayes_pls_golite062009
  • transcription factor binding
    		•  0.39685947299825 bayes_pls_golite062009
  • transcription factor activity
    		•  0.382098789505496 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle