Protein Overview: ERF2

General Information:
Name(s) found:	ERF2 / YLR246W [SGD]
Description(s) found: Found 24 descriptions. SHOW ALL	Subunit of a palmitoyltransferase, composed of Erf2p and Shr5p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole [SGD]
Organism:	Saccharomyces cerevisiae
Length:	359 amino acids
Gene Ontology:
Cellular Component:	integral to endoplasmic reticulum membrane [IDA] palmitoyltransferase complex [IPI]
Biological Process:	protein amino acid palmitoylation [IDA][IMP ] protein targeting to membrane [IMP]
Molecular Function:	protein-cysteine S-palmitoleyltransferase activity [IDA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALVSRRSTR SESTSITKEE HTGEGSLTKL FFRWLVTLEG DQDINDGKGY ISLPNVSNYI  60
   61 FFLGGRFRTV KGAKPLWLGV LLAIVCPMVL FSIFEAHKLW HTQNGYKVLV IFFYYFWVIT 120
  121 LASFIRTATS DPGVLPRNIH LSQLRNNYQI PQEYYNLITL PTHSSISKDI TIKYCPSCRI 180
  181 WRPPRSSHCS TCNVCVMVHD HHCIWVNNCI GKRNYRFFLI FLLGAILSSV ILLTNCAIHI 240
  241 ARESGGPRDC PVAILLLCYA GLTLWYPAIL FTYHIFMAGN QQTTREFLKG IGSKKNPVFH 300
  301 RVVKEENIYN KGSFLKNMGH LMLEPRGPSF VSARKPHEAG DWRFMDLSPA HSFEKIQKI

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		BRE2 ERF2 SDC1 SET1 SHG1 SPP1 SWD1 SWD3 YHI9 YLL023C
View Details	Qiu et al. (2008)		ERF2 SHR5 SWF1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
transporter activity	1.29200212594063	bayes_pls_golite062009
transmembrane transporter activity	1.08174821699506	bayes_pls_golite062009
protein binding	0.646210551989356	bayes_pls_golite062009
binding	0.50942388426238	bayes_pls_golite062009
catalytic activity	0.481338897251745	bayes_pls_golite062009
active transmembrane transporter activity	0.304549276964021	bayes_pls_golite062009
primary active transmembrane transporter activity	0.295075718640555	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	0.00673253349876157	bayes_pls_golite062009

No functions predicted.

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..163]	deduced	N/A	No confident structure predictions are available.
2	View Details	[164..297]	Pfam	37.008774	DHHC zinc finger domain No confident structure predictions are available.
3	View Details	[298..359]	deduced	N/A	No confident structure predictions are available.

Protein Overview: ERF2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: