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Protein Overview: SWF1

General Information:
Name(s) found: SWF1 / YDR126W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on all SNAREs; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; may have a role in vacuole fusion [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 336 amino acids

    Gene Ontology:
    Cellular Component: nuclear membrane-endoplasmic reticulum network [IDALink to PubMed article]
    integral to membrane [ISSLink to PubMed article]
    Biological Process: protein amino acid palmitoylation [IMPLink to PubMed articleLink to PubMed article]
    vacuole fusion, non-autophagic [IGILink to PubMed article]
    ascospore wall assembly [IMPLink to PubMed article]
    Molecular Function: protein-cysteine S-palmitoleyltransferase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWNLLFVLL IGFVVLILLS PVFKSTWPFS TFYRNVFQPF LVDDQKYRWK LHLVPLFYTS  60
   61 IYLYLVYTYH MRVESTIKNE LFLLERILIV PIIILPPVAL GILAMVSRAE DSKDHKSGST 120
  121 EEYPYDYLLY YPAIKCSTCR IVKPARSKHC SICNRCVLVA DHHCIWINNC IGKGNYLQFY 180
  181 LFLISNIFSM CYAFLRLWYI SLNSTSTLPR AVLTLTILCG CFTIICAIFT YLQLAIVKEG 240
  241 MTTNEQDKWY TIQEYMREGK LVRSLDDDCP SWFFKCTEQK DDAAEPLQDQ HVTFYSTNAY 300
  301 DHKHYNLTHY ITIKDASEIP NIYDKGTFLA NLTDLI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ERF2 SHR5 SWF1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..118] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [119..206] Pfam 34.920819 DHHC zinc finger domain No confident structure predictions are available.
    3 View Details [207..336] MSA 1.132996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • histone acetyltransferase activity
    		•  2.27787208911046 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  2.27787208911046 bayes_pls_golite062009
  • binding
    		•  2.26426010117912 bayes_pls_golite062009
  • protein transporter activity
    		•  1.41828558915713 bayes_pls_golite062009
  • protein binding
    		•  1.35218914294914 bayes_pls_golite062009
  • transporter activity
    		•  1.33264421804057 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.33198351552985 bayes_pls_golite062009
  • phosphoinositide binding
    		•  1.19034196920111 bayes_pls_golite062009
  • phospholipid binding
    		•  1.09010543599677 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.00368169716135 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.929797787738847 bayes_pls_golite062009
  • DNA binding
    		•  0.919146751776512 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.788911508084267 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  0.565596821175093 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  0.514633973697725 bayes_pls_golite062009
  • histone binding
    		•  0.335672312059968 bayes_pls_golite062009
    		• 0.308979985902751 bayes_pls_golite062009
  • phosphatidylinositol binding
    		•  0.251953910109229 bayes_pls_golite062009
  • ligase activity
    		•  0.161281682592326 bayes_pls_golite062009
  • transcription factor activity
    		•  0.0724499929149738 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0446344906851331 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.00643795263722946 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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