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Protein Overview: PSR2

General Information:
Name(s) found: PSR2 / YLR019W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Functionally redundant Psr1p homolog, a plasma membrane phosphatase involved in the general stress response; required with Psr1p and Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 397 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [ISSLink to PubMed article]
    Biological Process: response to stress [IGILink to PubMed article]
    Molecular Function: phosphoprotein phosphatase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFIANILCC SSDTSKTHRQ RQPPETNHNR NRNRKHSSNK AQTQGRKQKA TPNGDKMQYS  60
   61 TPEILLSSSD SGSNAGSKTM QENGNSGNGK LAPLSRDHSN NSYDEEKEYE DYNEGDVEMT 120
  121 EVNNAGEEEE EDDEAKEKQD HVVHEYNVDA DRNSSINDEA PPQQGLYQVG QEDMNPQYVA 180
  181 SSPDNDLNLI PTTEEDFSDL THLQPDQYHA PGYDTLLPPK LQEFQQKKCL ILDLDETLVH 240
  241 SSFKYMHSAD FVLPVEIDDQ VHNVYVIKRP GVDEFLNRVS QLYEVVVFTA SVSRYANPLL 300
  301 DTLDPNGTIH HRLFREACYN YEGNYIKNLS QIGRPLSETI ILDNSPASYI FHPQHAVPIS 360
  361 SWFSDTHDNE LLDIIPLLED LSSGNVLDVG SVLDVTI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) PSR1 PSR2 WHI2
    View Details Krogan NJ, et al. (2006) PSR1 PSR2 VHS2 WHI2
    View Details Ho Y, et al. (2002) FAA4 HXT6 HXT7 PSR2 SAC6

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run BIR1 No Comments Widlund PO, et al. (2005)
    View Run MLP2 #04 Alpha Factor Prep2 Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen UBC7 PSR2 2 Unpublished Fields Lab Data
    View Screen EUG1 PSR2 1 Unpublished Fields Lab Data
    View Screen CDC4 PSR2 1 Unpublished Fields Lab Data
    View Screen AIM13 PSR2 1 Unpublished Fields Lab Data
    View Screen YLR224W PSR2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..188] MSA 1.057944 View MSA. No confident structure predictions are available.
    2 View Details [189..397] Pfam 110.657577 NLI interacting factor-like phosphatase No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle