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Protein Overview: VHS2

General Information:
Name(s) found: VHS2 / YIL135C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Cytoplasmic protein of unknown function; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; similar to Mlf3p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 436 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: G1/S transition of mitotic cell cycle [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTSNHNQDH DSHVAAQREN DNNYMPPSPS MSESSMIFER NVEDPSYLYK TVSNNAANSL  60
   61 SRQSSRTSLF NHNNSSNRNF HNLSQRSSAV NLHLQPSRTN ESIASYQTYN PDFVVQTPLD 120
  121 HRRTLENFVP PALDAGCSIV TDDTTGLDDV DMVYSRRPST IGLDRALGRT RSLSSQSFDN 180
  181 ETSPAHPRSP NDHGSRLLRF YSYADMLSDD NNNNVSNATS TSSTANPLRR PPMQGHYSFS 240
  241 SSLLNSPSHL PSPPSASASP PQHMNFTNPF IISRRYSNTT INNANGGTSA GSTTGAALSR 300
  301 SPSNQQYLLK QQRSPSGSAR SRRNSNRPGS AANIMIGKPK SKFHMESSGS EGFSSEEEDN 360
  361 TMIERDKLNL KQKLQSQLAQ PPSIANMVND NHNNTNKHKN TINNNIKNSP AFTNSNPSSK 420
  421 SNSNSTITSM NPDTTK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) PSR1 PSR2 VHS2 WHI2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SCH9 VHS2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data VHS2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..281] MSA 1.00294 View MSA. No confident structure predictions are available.
    2 View Details [282..436] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle