Protein Overview: VPS51

General Information:
Name(s) found:	VPS51 / YKR020W [SGD]
Description(s) found: Found 30 descriptions. SHOW ALL	Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; links the (VFT/GARP) complex to the SNARE Tlg1p [SGD]
Organism:	Saccharomyces cerevisiae
Length:	164 amino acids
Gene Ontology:
Cellular Component:	GARP complex [IPI ] Golgi apparatus [IDA]
Biological Process:	vesicle organization [IMP] regulation of cell size [IMP] retrograde transport, endosome to Golgi [IDA] protein targeting to vacuole [IMP] budding cell apical bud growth [IDA]
Molecular Function:	protein binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEQISHKKS LRVSSLNKDR RLLLREFYNL ENEPNKGRQE ARIGEKASEA HSGEEQVTDV  60
   61 NIDTEANTEK PVKDDELSAT EEDLKEGSED AEEEIKNLPF KRLVQIHNKL LGKETETNNS 120
  121 IKNTIYENYY DLIKVNDLLK EITNANEDQI NKLKQTVESL IKEL

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Gavin AC, et al. (2002)		VPS51 VPS52 VPS53 VPS54
View Details	Qiu et al. (2008)		ENT5 VPS51 VPS52 VPS53 VPS54

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	STE50	VPS51	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	VPS51	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..164]	deduced	N/A	No confident structure predictions are available.
2	View Details	[79..164]	Pfam	15.309804	No description for PF08700.2 was found. No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2