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Protein Overview: SCW4

General Information:
Name(s) found: SCW4 / YGR279C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 386 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [IDALink to PubMed articleLink to PubMed article]
    Biological Process: conjugation with cellular fusion [IGILink to PubMed article]
    Molecular Function: glucosidase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLSNLIASA SLLSAATLAA PANHEHKDKR AVVTTTVQKQ TTIIVNGAAS TPVAALEENA  60
   61 VVNSAPAAAT STTSSAASVA TAAASSSENN SQVSAAASPA SSSAATSTQS SSSSQASSSS 120
  121 SSGEDVSSFA SGVRGITYTP YESSGACKSA SEVASDLAQL TDFPVIRLYG TDCNQVENVF 180
  181 KAKASNQKVF LGIYYVDQIQ DGVNTIKSAV ESYGSWDDVT TVSIGNELVN GNQATPSQVG 240
  241 QYIDSGRSAL KAAGYTGPVV SVDTFIAVIN NPELCDYSDY MAVNAHAYFD KNTVAQDSGK 300
  301 WLLEQIQRVW TACDGKKNVV ITESGWPSKG ETYGVAVPSK ENQKDAVSAI TSSCGADTFL 360
  361 FTAFNDYWKA DGAYGVEKYW GILSNE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) FAA4 FET3 GCD1 GCD11 GCD2 GCD6 GCD7 GCN3 LOS1 MET18 NMD5 PRO3 SCW4 SUI3 VAC8 VMA8

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)
    View Run MLP2 #34 Asynchronous SPB prep Keck JM, et al. (2011)
    View Run MLP2 #04 Alpha Factor Prep2 Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SCW4 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..96] deduced N/A No confident structure predictions are available.
    2 View Details [97..193]
    [208..225]
    [255..261]    		 PSI-BLAST 71.30103 Plant beta-glucanases
    3 View Details [194..207]
    [226..254]
    [262..284]
    [302..322]    		 PSI-BLAST 71.30103 Plant beta-glucanases
    4 View Details [285..301]
    [323..386]    		 PSI-BLAST 71.30103 Plant beta-glucanases

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • hydrolase activity, acting on glycosyl bonds
    		•  5.36248919165223 bayes_pls_golite062009
  • glucan 1,3-beta-glucosidase activity
    		•  5.16200085143699 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  4.11319792356479 bayes_pls_golite062009
  • glucosidase activity
    		•  3.69195576225095 bayes_pls_golite062009
  • beta-glucosidase activity
    		•  3.14931331494576 bayes_pls_golite062009
  • chitinase activity
    		•  2.45357334610104 bayes_pls_golite062009
  • alpha-amylase activity
    		•  2.09193270404736 bayes_pls_golite062009
  • amylase activity
    		•  2.03484942782894 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • hexosaminidase activity
    		•  1.26857012744249 bayes_pls_golite062009
  • hydrolase activity
    		•  1.22608062881808 bayes_pls_golite062009
  • receptor binding
    		•  0.709153600415243 bayes_pls_golite062009
  • binding
    		•  0.589888593043114 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.45065632894721 bayes_pls_golite062009
  • signal transducer activity
    		•  0.346648903090409 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.346648903090409 bayes_pls_golite062009
  • hyalurononglucosaminidase activity
    		•  0.123700697143861 bayes_pls_golite062009
  • pattern binding
    		•  0.113396113487931 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.10746671207581 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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