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Protein Overview: FLC3

General Information:
Name(s) found: FLC3 / YGL139W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 802 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    integral to membrane [ISSLink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: FAD transport [ISSLink to PubMed article]
    Molecular Function: FAD transmembrane transporter activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFLQVYKSS ALIGLIILLA SKVNLAEAKR KLVATSLVTC MENSQLSANS FDVVFNPDDR  60
   61 SLHYDLDMST QIDSYIFADI DVYAYGFKII TKNVDLCSIN WKQFCPVHPG NIQIDSIEYI 120
  121 SSEYVNEIPG IAYQVPDIDA YARVKITNNV SEYLACIQIY FSNGKTVSQI GVKWATAVVA 180
  181 GIGLLLSAIL STFGNSTAAS HISANTMSLF LYFQSVVVVA MQHVHRVPPI AAAWAENLVW 240
  241 SMGLIRISFM QRIFRWYVQS TGGTPSLYLT STSMSVLAQR SWQYLMELPL IKRATNVLYG 300
  301 NANTLIFRGI KRLGYKMGIE NTSIVCTGFT FFVLCGYVLA GFIIVFKCCV ELATRLGWIQ 360
  361 KARFWEFRKQ WRMILKGALL RYIYIGFVQL TILSFWEFTE RDSPAVIVIA CLFILLSCGL 420
  421 MLWAAWRTVF FARRSVALYN NPAALLYGDE YVLHKYGFFY TMFNANHYWW NIVLLSYIFV 480
  481 KSLLVGFAQA SGQTQVLFMF ILDLFYFVAI IYYKPYLDRP TNIMNILIAT VTVVNSFLFM 540
  541 FFSDLFNQSY KVAAIMGWIF FIMNAAFSFI LLMMILAFAG MMLFSKNPDL RFKPAKDDRT 600
  601 SFQRNTMKPE GTVNRSVANE LLALGNVAKD HDDNSDYESN DTGVNDELKQ AQDETTPTTV 660
  661 TSSDDNKPTF SEKILSKFSR PKNENASTDA LRVEAPKQQT FPHNLTNLSR ENLSTLGSKP 720
  721 YPGHTRSQSD AHNGLINSFE EEDTSSNTDP FHDSTEGDLL DTSSSDGGFR SQNYVRDDSI 780
  781 NSLGNNKQPL RKPPGFFDEG FM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data FLC3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..192] MSA 1.009955 View MSA. No confident structure predictions are available.
    2 View Details [193..301] deduced N/A No confident structure predictions are available.
    3 View Details [302..579] MSA 1.009936 View MSA. No confident structure predictions are available.
    4 View Details [580..749] MSA 1.009974 View MSA. No confident structure predictions are available.
    5 View Details [750..802] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • potassium channel activity
    		•  5.34623321286043 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  5.3457739160783 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  5.29167837952147 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  4.9171616807315 bayes_pls_golite062009
  • cation channel activity
    		•  4.79161681210355 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  4.75442765649412 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  4.73153984947535 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.54873661177894 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.46212583884101 bayes_pls_golite062009
  • ion channel activity
    		•  4.19986580228506 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  4.11043455536373 bayes_pls_golite062009
  • gated channel activity
    		•  4.10310997393268 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  4.09106677594218 bayes_pls_golite062009
  • channel activity
    		•  4.07346819712136 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  4.07346819712136 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.06857483006075 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  3.52286634234959 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  3.52286634234959 bayes_pls_golite062009
  • transporter activity
    		•  2.35657262831396 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.25147059981728 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.22751878261824 bayes_pls_golite062009
  • binding
    		•  1.96281708074635 bayes_pls_golite062009
  • G-protein activated inward rectifier potassium channel activity
    		•  1.65070971324325 bayes_pls_golite062009
  • hydrolase activity
    		•  1.63153428386052 bayes_pls_golite062009
  • protein binding
    		•  1.30086551295862 bayes_pls_golite062009
  • ATP-activated inward rectifier potassium channel activity
    		•  1.18849851204642 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.525578079825295 bayes_pls_golite062009
  • signal transducer activity
    		•  0.525578079825295 bayes_pls_golite062009
  • clathrin binding
    		•  0.50269928917354 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.448241458604601 bayes_pls_golite062009
  • actin binding
    		•  0.328787215513486 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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