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View Structure Prediction Details

Protein: FLC3
Organism: Saccharomyces cerevisiae
Length: 802 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FLC3.

Description E-value Query
Range
Subject
Range
FLC3 - Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER
FLC3_YEAST - Putative flavin carrier protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FLC3 P...
0.0 [1..802] [1..802]
gi|85104026 - gi|85104026|ref|XP_961648.1| hypothetical protein ( (AF294883) calcium-related spray protein [Neuros...
gi|32412097, gi|... - gi|9945012|gb|AAG03077.1| calcium-related spray protein [Neurospora crassa], gi|32412097|ref|XP_3265...
0.0 [19..647] [393..1052]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [19..647] [15..674]
PKD2_SCHPO - TRP-like ion channel pkd2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pkd2 PE=1 SV=1
pkd2 - TRP-like ion channel
0.0 [4..712] [1..694]

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Predicted Domain #1
Region A:
Residues: [1-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFLQVYKSS ALIGLIILLA SKVNLAEAKR KLVATSLVTC MENSQLSANS FDVVFNPDDR  60
   61 SLHYDLDMST QIDSYIFADI DVYAYGFKII TKNVDLCSIN WKQFCPVHPG NIQIDSIEYI 120
  121 SSEYVNEIPG IAYQVPDIDA YARVKITNNV SEYLACIQIY FSNGKTVSQI GVKWATAVVA 180
  181 GIGLLLSAIL ST

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
potassium channel activity 5.34623321286043 bayes_pls_golite062009
voltage-gated potassium channel activity 5.3457739160783 bayes_pls_golite062009
metal ion transmembrane transporter activity 5.29167837952147 bayes_pls_golite062009
voltage-gated cation channel activity 4.9171616807315 bayes_pls_golite062009
cation channel activity 4.79161681210355 bayes_pls_golite062009
voltage-gated ion channel activity 4.75442765649412 bayes_pls_golite062009
voltage-gated channel activity 4.73153984947535 bayes_pls_golite062009
cation transmembrane transporter activity 4.54873661177894 bayes_pls_golite062009
ion transmembrane transporter activity 4.46212583884101 bayes_pls_golite062009
ion channel activity 4.19986580228506 bayes_pls_golite062009
inward rectifier potassium channel activity 4.11043455536373 bayes_pls_golite062009
gated channel activity 4.10310997393268 bayes_pls_golite062009
substrate-specific channel activity 4.09106677594218 bayes_pls_golite062009
channel activity 4.07346819712136 bayes_pls_golite062009
passive transmembrane transporter activity 4.07346819712136 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.06857483006075 bayes_pls_golite062009
ligand-gated ion channel activity 3.52286634234959 bayes_pls_golite062009
ligand-gated channel activity 3.52286634234959 bayes_pls_golite062009
transporter activity 2.35657262831396 bayes_pls_golite062009
transmembrane transporter activity 2.25147059981728 bayes_pls_golite062009
substrate-specific transporter activity 2.22751878261824 bayes_pls_golite062009
binding 1.96281708074635 bayes_pls_golite062009
G-protein activated inward rectifier potassium channel activity 1.65070971324325 bayes_pls_golite062009
hydrolase activity 1.63153428386052 bayes_pls_golite062009
protein binding 1.30086551295862 bayes_pls_golite062009
ATP-activated inward rectifier potassium channel activity 1.18849851204642 bayes_pls_golite062009
molecular transducer activity 0.525578079825295 bayes_pls_golite062009
signal transducer activity 0.525578079825295 bayes_pls_golite062009
clathrin binding 0.50269928917354 bayes_pls_golite062009
cytoskeletal protein binding 0.448241458604601 bayes_pls_golite062009
actin binding 0.328787215513486 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [193-301]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGNSTAASHI SANTMSLFLY FQSVVVVAMQ HVHRVPPIAA AWAENLVWSM GLIRISFMQR  60
   61 IFRWYVQSTG GTPSLYLTST SMSVLAQRSW QYLMELPLIK RATNVLYGN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [302-579]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANTLIFRGIK RLGYKMGIEN TSIVCTGFTF FVLCGYVLAG FIIVFKCCVE LATRLGWIQK  60
   61 ARFWEFRKQW RMILKGALLR YIYIGFVQLT ILSFWEFTER DSPAVIVIAC LFILLSCGLM 120
  121 LWAAWRTVFF ARRSVALYNN PAALLYGDEY VLHKYGFFYT MFNANHYWWN IVLLSYIFVK 180
  181 SLLVGFAQAS GQTQVLFMFI LDLFYFVAII YYKPYLDRPT NIMNILIATV TVVNSFLFMF 240
  241 FSDLFNQSYK VAAIMGWIFF IMNAAFSFIL LMMILAFA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [580-749]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMMLFSKNPD LRFKPAKDDR TSFQRNTMKP EGTVNRSVAN ELLALGNVAK DHDDNSDYES  60
   61 NDTGVNDELK QAQDETTPTT VTSSDDNKPT FSEKILSKFS RPKNENASTD ALRVEAPKQQ 120
  121 TFPHNLTNLS RENLSTLGSK PYPGHTRSQS DAHNGLINSF EEEDTSSNTD 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [750-802]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFHDSTEGDL LDTSSSDGGF RSQNYVRDDS INSLGNNKQP LRKPPGFFDE GFM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle