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Protein Overview: pkd2

General Information:
Name(s) found: pkd2 / SPAC1F7.03 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • TRP-like ion channel [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 710 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IDALink to PubMed article]
    integral to Golgi membrane [IDALink to PubMed article]
    plasma membrane of cell tip [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: fungal-type cell wall biogenesis [IMPLink to PubMed article]
    establishment of protein localization in plasma membrane [IMPLink to PubMed article]
    cellular cell wall organization [IMPLink to PubMed article]
    calcium ion transmembrane transport [IMPLink to PubMed article]
    cell wall repair [IMPLink to PubMed article]
    regulation of intracellular protein transport [IMPLink to PubMed article]
    regulation of exocytosis [IMPLink to PubMed article]
    regulation of fungal-type cell wall biogenesis [IPILink to PubMed article]
    cellular calcium ion homeostasis [ICLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    calcium channel activity [IMPLink to PubMed article]
    calcium ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLWRSPLLL LVVVVELFSW ADALTRFISA DSLSTCMTDS QLSASKLYAS YFPDNQSVAF  60
   61 DISIQSLVST NVSIDVDISA YGIEIKKVID PCDMEISGFC PMQTGNIALS GSHTLTGEAL 120
  121 SILDSIPSIA YTVPDLDAVV TINIYESDTN TQLACVRTTV QNGRSVYHRA VYWVMCMVIG 180
  181 IPLLIFLLIS PVLQTPALWE IVETMITLFQ FAQIQALYSM MATSLPAIIY SWGRNFMWSM 240
  241 GIIRIGFMQD VFTWYVKSTG GTPSTLVDLG IHANVALAKR GIDLGSLAKR ATTTVTTSTS 300
  301 DSITLRGIKR ISYMMGIETT NFFATGFSFF IILLFFSLLV AMASRFIVEM VLLASRNQAL 360
  361 KKQRIRLYWK SISKGFFYRV IFVGFTQMSV LSMWEIYTRD SSALAFLSMY VIVDMAVLLC 420
  421 YAFVRTIQII RKTGPYSHPD VLYNLYSDTQ HLMRWGFMYV QLDVRFFYFT FPLLLITLVR 480
  481 SMFIGFGQGS PKVQGCAMFG ISVVVFALMV ILRPYATKHM NTLHIGVALM NLISGSFILV 540
  541 MCQAFYVEEL ARQVIGIIFF ALNAITMLLL ILGIFIRTLI VLFRKSGHGT YYRILDDQSE 600
  601 KATSYNKSIK DMSSSDMAFS DPAYSGTTLR SSVDLNTPEY PFSNRNDSDS TFTNNKYVSP 660
  661 WDAIEEASYA NLRGNTDVEQ PFMESDYTRI SENNNNAERR RKPLPNNAFR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..150] FFAS03 1.6 Crystal Structure of mouse GM2- activator Protein
    2 View Details [151..400] deduced N/A No confident structure predictions are available.
    3 View Details [401..588] MSA 15.129996 View MSA. No confident structure predictions are available.
    4 View Details [589..710] MSA 1.069987 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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