YRC Public Data Repository - Protein Structure Prediction

Protein:	pkd2
Organism:	Schizosaccharomyces pombe
Length:	710 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pkd2.

Description	E-value	Query Range	Subject Range
FLC3 - Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER FLC3_YEAST - Putative flavin carrier protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FLC3 P...	738.0	[0..1]	[705..4]
gi\|46137303, gi\|... - gi\|46137303\|ref\|XP_390343.1\| hypothetical protein FG10167.1 [Gibberella zeae PH-1], gi\|42545226\|gb\|E...	737.0	[0..3]	[705..1]
gi\|68491536, gi\|... - gi\|68491545\|ref\|XP_710428.1\| conserved fungal protein CFP1 [Candida albicans SC5314], gi\|68491536\|re... orf19.1813, orf1... - FLC2 CGDID:CAL0001600 Assembly 19, Contig19-10129 (3107, 672) CDS, reverse complemented, translated ...	724.0	[0..21]	[709..20]
gi\|67522987, gi\|... - gi\|67522987\|ref\|XP_659554.1\| hypothetical protein AN1950.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	714.0	[0..3]	[707..1]
gi\|85104026 - gi\|85104026\|ref\|XP_961648.1\| hypothetical protein ( (AF294883) calcium-related spray protein [Neuros... gi\|32412097, gi\|... - gi\|9945012\|gb\|AAG03077.1\| calcium-related spray protein [Neurospora crassa], gi\|32412097\|ref\|XP_3265...	711.0	[0..2]	[705..378]
gi\|164426218, gi... - gi\|164426218\|ref\|XP_961648.2\| hypothetical protein NCU01036 [Neurospora crassa OR74A], gi\|157071246\|... gi\|16415970 - gi\|16415970\|emb\|CAD01103.1\| conserved hypothetical protein [Neurospora crassa]	689.0	[0..19]	[705..19]

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Predicted Domain #1

Region A:
Residues: [1-150]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLWRSPLLL LVVVVELFSW ADALTRFISA DSLSTCMTDS QLSASKLYAS YFPDNQSVAF  60
   61 DISIQSLVST NVSIDVDISA YGIEIKKVID PCDMEISGFC PMQTGNIALS GSHTLTGEAL 120
  121 SILDSIPSIA YTVPDLDAVV TINIYESDTN

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.6
Match:	2agcA
Description:	Crystal Structure of mouse GM2- activator Protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [151-400]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQLACVRTTV QNGRSVYHRA VYWVMCMVIG IPLLIFLLIS PVLQTPALWE IVETMITLFQ  60
   61 FAQIQALYSM MATSLPAIIY SWGRNFMWSM GIIRIGFMQD VFTWYVKSTG GTPSTLVDLG 120
  121 IHANVALAKR GIDLGSLAKR ATTTVTTSTS DSITLRGIKR ISYMMGIETT NFFATGFSFF 180
  181 IILLFFSLLV AMASRFIVEM VLLASRNQAL KKQRIRLYWK SISKGFFYRV IFVGFTQMSV 240
  241 LSMWEIYTRD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [401-588]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSALAFLSMY VIVDMAVLLC YAFVRTIQII RKTGPYSHPD VLYNLYSDTQ HLMRWGFMYV  60
   61 QLDVRFFYFT FPLLLITLVR SMFIGFGQGS PKVQGCAMFG ISVVVFALMV ILRPYATKHM 120
  121 NTLHIGVALM NLISGSFILV MCQAFYVEEL ARQVIGIIFF ALNAITMLLL ILGIFIRTLI 180
  181 VLFRKSGH

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [589-710]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTYYRILDDQ SEKATSYNKS IKDMSSSDMA FSDPAYSGTT LRSSVDLNTP EYPFSNRNDS  60
   61 DSTFTNNKYV SPWDAIEEAS YANLRGNTDV EQPFMESDYT RISENNNNAE RRRKPLPNNA 120
  121 FR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits