Protein Overview: YFL054C

General Information:
Name(s) found:	YFL054C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|836701\|dbj\|BAA09187.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] gi\|51012657\|gb\|AAT92622.1\| YFL054C [Saccharomyces cerevisiae] [NCBI NR] gi\|14318465\|ref\|NP_116601.1\| Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol; Yfl054cp [Saccharomyces cerevisiae] [NCBI NR] gi\|1175958\|sp\|P43549.1\|YFF4_YEAST RecName: Full=Uncharacterized membrane protein YFL054C [NCBI NR] pir\|\|S56201 probable membrane protein YFL054c - yeast (Saccharomyces cerevisiae) [NCBI NR] Uncharacterized membrane protein YFL054C OS=Saccharomyces cerevisiae GN=YFL054C PE=1 SV=1 [Swiss-Prot] Putative channel protein, exgression is glucose repressed by Mig1 and Mig2 [mips] Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol [SGD] YFL054C, Chr VI from 20847-22787, reverse complement [yeast_orfs2] Chr VI from 20847-22787, reverse complement [yeastorf3.fasta] Chr VI from 22787-20847, reverse complement [yeastorf5.fasta] (P43549) Hypothetical 70.5 kDa protein in AGP3-DAK3 intergenic region [4932.FASTACCERV.txt] YFL054C SGDID:S0001840, Chr VI from 22787-20847, reverse complement, Uncharacterized ORF [yeastflysequest.fasta] Yfl054cp [Saccharomyces cerevisiae]gi\|51012657\|gb\|AAT92622.1\| YFL054C [Saccharomyces cerevisiae]gi\|1175958\|sp\|P43549\|YFF4_YEAST Hypothetical 70.5 kDa protein in AGP3-DAK3 intergenic regiongi\|1084712\|pir\|\|S56201 probable membrane protein YFL054c - yeast [nrdb_11152004_Chlamydomonas] YFL054C SGDID:S000001840, Chr VI from 22787-20847, reverse complement, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YFL054C SGDID:S000001840, Chr VI from 22787-20847, reverse complement, Uncharacterized ORF, "Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol" [yeast-contam.fasta] Uncharacterized membrane protein YFL054C [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol; Yfl054cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YFL054C [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Uncharacterized membrane protein YFL054C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YFL054C PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] YFL054C SGDID:S000001840, Chr VI from 22787-20847, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol" [yeast-030211-contam.fasta] YFL054C SGDID:S000001840, Chr VI from 22787-20847, Genome Release 64-2-1, reverse complement, Uncharacterized ORF, "Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol" [20141208_orf_trans.fasta] TR5954\|c0_g1_i1\|g.4141 ORF TR5954\|c0_g1_i1\|g.4141 TR5954\|c0_g1_i1\|m.4141 type:complete len:647 (+) TR5954\|c0_g1_i1:5303-7243(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] ID=asmbl_9445\|g.5661 ORF ID=asmbl_9445\|g.5661 ID=asmbl_9445\|m.5661 type:complete len:647 (+) ID=asmbl_9445:5303-7243(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	646 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [ISS]
Biological Process:	water transport [ISS]
Molecular Function:	glycerol transmembrane transporter activity [ISS] water channel activity [ISS] transporter activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYESGRSSS SSESTRPPTL KEEPNGKIAW EESVKKSREN NENDSTLLRR KLGETRKAIE  60
   61 TGGSSRNKLS ALTPLKKVVD ERKDSVQPQV PSMGFTYSLP NLKTLNSFSD AEQARIMQDY 120
  121 LSRGVNQGNS NNYVDPLYRQ LNPTMGSSRN RPVWSLNQPL PHVLDRGLAA KMIQKNMDAR 180
  181 SRASSRRGST DISRGGSTTS VKDWKRLLRG AAPGKKLGDI EAQTQRDNTV GADVKPTKLE 240
  241 PENPQKPSNT HIENVSRKKK RTSHNVNFSL GDESYASSIA DAESRKLKNM QTLDGSTPVY 300
  301 TKLPEELIEE ENKSTSALDG NEIGASEDED ADIMTFPNFW AKIRYHMREP FAEFLGTLVL 360
  361 VIFGVGGNLQ ATVTKGSGGS YESLSFAWGF GCMLGVYVAG GISGGHINPA VTISMAIFRK 420
  421 FPWKKVPVYI VAQIIGAYFG GAMAYGYFWS SITEFEGGPH IRTTATGACL FTDPKSYVTW 480
  481 RNAFFDEFIG ASILVGCLMA LLDDSNAPPG NGMTALIIGF LVAAIGMALG YQTSFTINPA 540
  541 RDLGPRIFAS MIGYGPHAFH LTHWWWTWGA WGGPIAGGIA GALIYDIFIF TGCESPVNYP 600
  601 DNGYIENRVG KLLHAEFHQN DGTVSDESGV NSNSNTGSKK SVPTSS

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		ELM1 GIS4 MRP8 YEL043W YFL054C
View Details	Qiu et al. (2008)		AQY1 YFL054C

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#29 Asynchronous Prep5-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..236]	MSA	2.004996	View MSA. No confident structure predictions are available.
2	View Details	[237..326]	deduced	N/A	No confident structure predictions are available.
3	View Details	[327..460]	PSI-BLAST	496.70927	Glycerol uptake facilitator protein GlpF
4	View Details	[461..646]	PSI-BLAST	496.70927	Glycerol uptake facilitator protein GlpF

Protein Overview: YFL054C

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: