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Protein Overview: HMF1

General Information:
Name(s) found: HMF1 / YER057C [SGD]
Description(s) found:
Found 39 descriptions.
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  • Member of the p14.5 protein family with similarity to Mmf1p, functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 129 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTTLTPVIC ESAPAAAASY SHAMKVNNLI FLSGQIPVTP DNKLVEGSIA DKAEQVIQNI  60
   61 KNVLEASNSS LDRVVKVNIF LADINHFAEF NSVYAKYFNT HKPARSCVAV AALPLGVDME 120
  121 MEAIAAERD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) DSK2 HMF1 NPL4 RAD23 SHP1 TSL1 UBI4 UFD2 YDR049W

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..129] PSI-BLAST 583.221849 Highdosage growth inhibitor YER057cp (YEO7 YEAST)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.87868720745411 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.22360393331335 bayes_pls_golite062009
  • endonuclease activity
    		•  1.15998284441833 bayes_pls_golite062009
  • nuclease activity
    		•  1.15733739916248 bayes_pls_golite062009
  • catalytic activity
    		•  1.00848565859536 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.464097297780191 bayes_pls_golite062009
  • protein binding
    		•  0.378484263251583 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle