YRC Public Data Repository - Protein Structure Prediction

Protein:	HMF1
Organism:	Saccharomyces cerevisiae
Length:	129 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HMF1.

Description	E-value	Query Range	Subject Range
gi\|3257265, gi\|1... - gi\|3257265\|dbj\|BAA29948.1\| 137aa long hypothetical protein [Pyrococcus horikoshii OT3], gi\|14590714\|... gi\|7444996 - gi\|7444996\|pir\|\|B71136 hypothetical protein PH0854 - Pyrococcus horikoshii	9.0E-47	[5..128]	[13..137]
RIDA_PYRFU - 2-iminobutanoate/2-iminopropanoate deaminase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / ...	2.0E-46	[5..128]	[2..126]
Y1251_PYRAB, YC5... - (Q9UZA3) Hypothetical UPF0076 protein PYRAB12510, UPF0076 protein PYRAB12510 OS=Pyrococcus abyssi GN... Y1251_PYRAB - RutC family protein PYRAB12510 OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=PYRAB12510 PE=3 SV=1	3.0E-45	[3..128]	[1..127]
gi\|182380467, gi... - gi\|182380467\|gb\|EDT77946.1\| putative endoribonuclease L-PSP [Clostridium perfringens NCTC 8239], gi\|... gi\|177907997, gi... - gi\|182626667\|ref\|ZP_02954410.1\| putative endoribonuclease L-PSP [Clostridium perfringens D str. JGS1... gi\|18144673, gi\|... - gi\|18309994\|ref\|NP_561928.1\| putative endoribonuclease L-PSP [Clostridium perfringens str. 13], gi\|1... gi\|110675897, gi... - gi\|110801250\|ref\|YP_695713.1\| putative endoribonuclease L-PSP [Clostridium perfringens ATCC 13124], ... gi\|170711189, gi... - gi\|170711189\|gb\|EDT23371.1\| putative endoribonuclease L-PSP [Clostridium perfringens B str. ATCC 362... gi\|168215060, gi... - gi\|170713533\|gb\|EDT25715.1\| putative endoribonuclease L-PSP [Clostridium perfringens CPE str. F4969]...	2.0E-43	[3..128]	[1..126]
gi\|227247526, gi... - gi\|227556090\|ref\|ZP_03986137.1\| endoribonuclease L-PSP [Staphylococcus aureus subsp. aureus MN8], gi... gi\|227900617, gi... - gi\|227900617\|ref\|ZP_04018422.1\| endoribonuclease L-PSP [Staphylococcus aureus subsp. aureus TCH60], ... gi\|253316226 - gi\|253316226\|ref\|ZP_04839439.1\| hypothetical protein SauraC_08821 [Staphylococcus aureus subsp. aure... gi\|90429314, gi\|... - gi\|90587079\|ref\|ZP_01242755.1\| YjgF-like protein [Staphylococcus aureus subsp. aureus JH9], gi\|90429... gi\|253725314, gi... - gi\|253730964\|ref\|ZP_04865129.1\| endoribonuclease L-PSP [Staphylococcus aureus subsp. aureus USA300_T... gi\|255005290 - gi\|255005290\|ref\|ZP_05143891.2\| hypothetical protein SauraM_02445 [Staphylococcus aureus subsp. aure... gi\|13700387, gi\|... - gi\|15926174\|ref\|NP_373707.1\| hypothetical protein SA0455 [Staphylococcus aureus subsp. aureus N315],... gi\|49482724, gi\|... - gi\|49482724\|ref\|YP_039948.1\| putative regulatory protein [Staphylococcus aureus subsp. aureus MRSA25... gi\|14246265, gi\|... - gi\|15923487\|ref\|NP_371021.1\| translation initiation inhibitor-like protein [Staphylococcus aureus su... gi\|25303238 - pir\|\|B89816 hypothetical protein SA0455 [imported] - Staphylococcus aureus (strain N315) gi\|269202117\|ref... - endoribonuclease L-PSP, putative [Staphylococcus aureus subsp. aureus ED98] gi\|90584044, gi\|... - gi\|90584044\|ref\|ZP_01239790.1\| YjgF-like protein [Staphylococcus aureus subsp. aureus JH1], gi\|90426... gi\|156720960, gi... - gi\|156978825\|ref\|YP_001441084.1\| translation initiation inhibitor homologue [Staphylococcus aureus s...	5.0E-43	[5..129]	[1..125]
gi\|25303224 - pir\|\|G83657 translation initiation inhibitor BH0063 [imported] - Bacillus halodurans (strain C-125) gi\|10172675, gi\|... - gi\|15612626\|ref\|NP_240929.1\| translation initiation inhibitor [Bacillus halodurans C-125], gi\|101726...	8.0E-43	[5..128]	[1..124]
YABJ_BACSU - (P37552) UPF0076 protein yabJ	1.0E-42	[6..128]	[2..124]
gi\|25533215 - pir\|\|AF2289 hypothetical protein all3869 [imported] - Nostoc sp. (strain PCC 7120) gi\|17231361, gi\|... - gi\|17231361\|ref\|NP_487909.1\| hypothetical protein all3869 [Nostoc sp. PCC 7120], gi\|17133003\|dbj\|BAB...	1.0E-42	[2..129]	[244..375]
gi\|221312179 - gi\|221312179\|ref\|ZP_03593984.1\| hypothetical protein BsubsN3_00240 [Bacillus subtilis subsp. subtili... YABJ_BACSU - RutC family protein yabJ OS=Bacillus subtilis GN=yabJ PE=1 SV=3 RIDA_BACSU - 2-iminobutanoate/2-iminopropanoate deaminase OS=Bacillus subtilis (strain 168) GN=yabJ PE=1 SV=3 gi\|221317112 - gi\|221317112\|ref\|ZP_03598406.1\| hypothetical protein BsubsJ_00240 [Bacillus subtilis subsp. subtilis... gi\|221321375 - gi\|221321375\|ref\|ZP_03602669.1\| hypothetical protein BsubsS_00240 [Bacillus subtilis subsp. subtilis...	1.0E-42	[3..128]	[1..125]
gi\|16024898 - gi\|16024898\|gb\|AAL11406.1\| YabJ [Staphylococcus epidermidis]	1.0E-41	[5..129]	[1..125]

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Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTTLTPVIC ESAPAAAASY SHAMKVNNLI FLSGQIPVTP DNKLVEGSIA DKAEQVIQNI  60
   61 KNVLEASNSS LDRVVKVNIF LADINHFAEF NSVYAKYFNT HKPARSCVAV AALPLGVDME 120
  121 MEAIAAERD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	583.221849
Match:	1jd1A_
Description:	Highdosage growth inhibitor YER057cp (YEO7 YEAST)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.87868720745411	bayes_pls_golite062009
ribonuclease activity	1.22360393331335	bayes_pls_golite062009
endonuclease activity	1.15998284441833	bayes_pls_golite062009
nuclease activity	1.15733739916248	bayes_pls_golite062009
catalytic activity	1.00848565859536	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.464097297780191	bayes_pls_golite062009
protein binding	0.378484263251583	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: