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Protein Overview: DLD2

General Information:
Name(s) found: DLD2 / YDL178W [SGD]
Description(s) found:
Found 28 descriptions.
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  • D-lactate dehydrogenase, located in the mitochondrial matrix [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 530 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: lactate metabolic process [TASLink to PubMed article]
    Molecular Function: D-lactate dehydrogenase (cytochrome) activity [IDALink to PubMed article]
    actin binding [IMPLink to PubMed article][IPILink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRNILVRST GSNFKFAGRY MKSSALLGYY RRVNYYSTKI QTRLTSENYP DVHRDPRFKK  60
   61 LTSDDLNYFK SILSEQEILR ASESEDLSFY NEDWMRKYKG QSKLVLRPKS VEKVSLILNY 120
  121 CNDEKIAVVP QGGNTGLVGG SVPIFDELIL SLANLNKIRD FDPVSGILKC DAGVILENAN 180
  181 NYVMEQNYMF PLDLGAKGSC HVGGVVATNA GGLRLLRYGS LHGSVLGLEV VMPNGQIVNS 240
  241 MHSMRKDNTG YDLKQLFIGS EGTIGIITGV SILTVPKPKA FNVSYLSVES FEDVQKVFVR 300
  301 ARQELSEILS AFEFMDAKSQ VLAKSQLKDA AFPLEDEHPF YILIETSGSN KDHDDSKLET 360
  361 FLENVMEEGI VTDGVVAQDE TELQNLWKWR EMIPEASQAN GGVYKYDVSL PLKDLYSLVE 420
  421 ATNARLSEAE LVGDSPKPVV GAIGYGHVGD GNLHLNVAVR EYNKNIEKTL EPFVYEFVSS 480
  481 KHGSVSAEHG LGFQKKNYIG YSKSPEEVKM MKDLKVHYDP NGILNPYKYI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) ABP1 AIP1 ARC40 ARP2 BEM1 BUD6 CAP1 CAP2 COF1 CRN1 DLD2 GLK1 LAS17 OYE2 PAN1 PFY1 RVS167 SAC6 SLA1 SLA2 SRV2 TPM1 TPM2 TWF1 VRP1
    View Details Qiu et al. (2008) ABP1 ACT1 COF1 DLD2 MDH1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data DLD2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..277]
    [490..530]    		 PSI-BLAST 144.134302 Flavoprotein subunit of p-cresol methylhydroxylase
    2 View Details [278..489] PSI-BLAST 144.134302 Flavoprotein subunit of p-cresol methylhydroxylase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle