YRC Public Data Repository - Protein Structure Prediction

Protein:	DLD2
Organism:	Saccharomyces cerevisiae
Length:	530 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DLD2.

Description	E-value	Query Range	Subject Range
gi\|151941827 - gi\|151941827\|gb\|EDN60183.1\| D-lactate ferricytochrome c oxidoreductase [Saccharomyces cerevisiae YJM... DLD2_YEAST - D-lactate dehydrogenase [cytochrome] 2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 20450... DLD2 - D-lactate dehydrogenase, located in the mitochondrial matrix gi\|190405174 - gi\|190405174\|gb\|EDV08441.1\| D-lactate dehydrogenase 2, mitochondrial precursor [Saccharomyces cerevi...	0.0	[1..530]	[1..530]
gi\|7270588, gi\|4... - gi\|7270588\|emb\|CAB80306.1\| actin interacting protein [Arabidopsis thaliana], gi\|4006920\|emb\|CAB16815...	0.0	[46..530]	[48..517]
gi\|25323065 - pir\|\|B83991 glycolate oxidase subunit BH2730 [imported] - Bacillus halodurans (strain C-125) gi\|10175351, gi\|... - gi\|15615293\|ref\|NP_243596.1\| glycolate oxidase subunit [Bacillus halodurans C-125], gi\|10175351\|dbj\|...	0.0	[61..529]	[2..457]
gi\|221315135 - gi\|221315135\|ref\|ZP_03596940.1\| hypothetical protein BsubsN3_15562 [Bacillus subtilis subsp. subtili... GLCD_BACSU - Glycolate oxidase subunit GlcD OS=Bacillus subtilis (strain 168) GN=glcD PE=3 SV=1 gi\|221324335 - gi\|221324335\|ref\|ZP_03605629.1\| hypothetical protein BsubsS_15627 [Bacillus subtilis subsp. subtilis... GLCD_BACSU - Glycolate oxidase subunit glcD OS=Bacillus subtilis GN=glcD PE=3 SV=1 gi\|221320053 - gi\|221320053\|ref\|ZP_03601347.1\| hypothetical protein BsubsJ_15468 [Bacillus subtilis subsp. subtilis...	0.0	[61..529]	[2..457]
gi\|254693190 - gi\|254693190\|ref\|ZP_05155018.1\| hypothetical protein Babob3T_00682 [Brucella abortus bv. 3 str. Tuly... gi\|225851942, gi... - gi\|225851942\|ref\|YP_002732175.1\| hypothetical protein BMEA_A0437 [Brucella melitensis ATCC 23457], g... gi\|254709556 - gi\|254709556\|ref\|ZP_05171367.1\| hypothetical protein BpinB_04639 [Brucella pinnipedialis B2/94] gi\|254707861 - gi\|254707861\|ref\|ZP_05169689.1\| hypothetical protein BpinM_13066 [Brucella pinnipedialis M163/99/10] gi\|254703760 - gi\|254703760\|ref\|ZP_05165588.1\| hypothetical protein Bsuib36_07522 [Brucella suis bv. 3 str. 686] gi\|254701214 - gi\|254701214\|ref\|ZP_05163042.1\| hypothetical protein Bsuib55_10192 [Brucella suis bv. 5 str. 513] gi\|161335192, gi... - gi\|161618381\|ref\|YP_001592268.1\| hypothetical protein BCAN_A0411 [Brucella canis ATCC 23365], gi\|161... gi\|254716619 - gi\|254716619\|ref\|ZP_05178430.1\| hypothetical protein BcetM_09393 [Brucella ceti M13/05/1] gi\|254713026 - gi\|254713026\|ref\|ZP_05174837.1\| hypothetical protein BcetM6_06599 [Brucella ceti M644/93/1] gi\|17987810, gi\|... - gi\|17987810\|ref\|NP_540444.1\| glycolate oxidase subunit GLCD [Brucella melitensis 16M], gi\|17983536\|g... gi\|25323106 - pir\|\|AI3442 glycolate oxidase chain glcD [imported] - Brucella melitensis (strain 16M) gi\|23347199, gi\|... - gi\|23501310\|ref\|NP_697437.1\| oxidoreductase, FAD-binding [Brucella suis 1330], gi\|23347199\|gb\|AAN293...	0.0	[61..530]	[2..470]
YN53_SCHPO - Putative D-lactate dehydrogenase C713.03, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / A... SPBC713.03 - D-lactate dehydrogenase (cytochrome)	0.0	[41..530]	[31..526]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[39..530]	[57..532]
gi\|17429686 - gi\|17429686\|emb\|CAD16371.1\| putative d-lactate dehydrogenase (cytochrome) oxidoreductase protein [Ra... gi\|17547383 - gi\|17547383\|ref\|NP_520785.1\| putative D-lactate dehydrogenase (cytochrome) oxidoreductase protein [R...	0.0	[50..529]	[2..469]

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Predicted Domain #1

Region A:
Residues: [1-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRNILVRST GSNFKFAGRY MKSSALLGYY RRVNYYSTKI QTRLTSENYP DVHRDPRFKK  60
   61 LTSDDLNYFK SILSEQEILR ASESEDLSFY NEDWMRKYKG QSKLVLRPKS VEKVSLILNY 120
  121 CNDEKIAVVP QGGNTGLVGG SVPIFDELIL SLANLNKIRD FDPVSGILKC DAGVILENAN 180
  181 NYVMEQNYMF PLDLGAKGSC HVGGVVATNA GGLRLLRYGS LHGSVLGLEV VMPNGQIVNS 240
  241 MHSMRKDNTG YDLKQLFIGS EGTIGIITGV SILTVPK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [490-530]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLGFQKKNYI GYSKSPEEVK MMKDLKVHYD PNGILNPYKY I

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	144.134302
Match:	1diiA_
Description:	Flavoprotein subunit of p-cresol methylhydroxylase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [278-489]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKAFNVSYLS VESFEDVQKV FVRARQELSE ILSAFEFMDA KSQVLAKSQL KDAAFPLEDE  60
   61 HPFYILIETS GSNKDHDDSK LETFLENVME EGIVTDGVVA QDETELQNLW KWREMIPEAS 120
  121 QANGGVYKYD VSLPLKDLYS LVEATNARLS EAELVGDSPK PVVGAIGYGH VGDGNLHLNV 180
  181 AVREYNKNIE KTLEPFVYEF VSSKHGSVSA EH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	144.134302
Match:	1diiA_
Description:	Flavoprotein subunit of p-cresol methylhydroxylase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits