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Protein Overview: DCC1

General Information:
Name(s) found: DCC1 / YCL016C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 380 amino acids

    Gene Ontology:
    Cellular Component: DNA replication factor C complex [IPILink to PubMed article]
    Biological Process: mitotic sister chromatid cohesion [IMPLink to PubMed article]
    telomere maintenance [IMPLink to PubMed articleLink to PubMed article]
    response to DNA damage stimulus [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSINLHSAPE YDPSYKLIQL TPELLDIIQD PVQNHQLRFK SLDKDKSEVV LCSHDKTWVL  60
   61 KQRKHSNTVL LMREFVPEQP ITFDETLLFG LSKPYMDVVG FAKTESEFET RETHGELNLN 120
  121 SVPIYNGELD FSDKIMKRSS TKVIGTLEEL LENSPCSALE GISKWHKIGG SVKDGVLCIL 180
  181 SQDFLFKALH VLLMSAMAES LDLQHLNVED THHAVGKDIE DEFNPYTREI IETVLNKFAV 240
  241 QEQEAENNTW RLRIPFIAQW YGIQALRKYV SGISMPIDEF LIKWKSLFPP FFPCDIDIDM 300
  301 LRGYHFKPTD KTVQYIAKST LPMDPKERFK VLFRLQSQWD LEDIKPLIEE LNSRGMKIDS 360
  361 FIMKYARRKR LGKKTVVTSR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) CTF8 DCC1
    View Details Krogan NJ, et al. (2006) AQR1 CTF18 CTF8 DCC1
    View Details Qiu et al. (2008) CTF18 DCC1 RFC4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data DCC1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..223] MSA 1.007947 View MSA. No confident structure predictions are available.
    2 View Details [224..380] MSA 1.007965 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle