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Protein Overview: PBY1

General Information:
Name(s) found: PBY1 / YBR094W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Putative tubulin tyrosine ligase associated with P-bodies [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 753 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    cytoplasmic mRNA processing body [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    [NOT]mRNA catabolic process [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVLITNDDG PLSDQFSPYI RPFIQHIKRN YPEWKITVCV PHVQKSWVGK AHLAGKNLTA  60
   61 QFIYSKVDAE DNTFWGPFIQ PQIRSENSKL PYVLNAEIPK DTIEWILIDG TPASCANIGL 120
  121 HLLSNEPFDL VLSGPNVGRN TSAAYITSSG TVGGAMESVI TGNTKAIAIS WAYFNGLKNV 180
  181 SPLLMEKASK RSLDVIKHLV KNWDPKTDLY SINIPLVESL SDDTKVYYAP IWENRWIPIF 240
  241 NGPHINLENS FAEIEDGNES SSISFNWAPK FGAHKDSIHY MDEYKDRTVL TDAEVIESEM 300
  301 ISVTPMKATF KGVNHLLGEL KLTEEENNLS KTNNLIVVSI DPMEYIYKPL THALKKYLPQ 360
  361 VEIVSNLPEF DNGGCEKEMK VFHYGDYEQL DMDKLMELPN NYFTNSYIYR KALIRKHFLS 420
  421 HTIQTYTAKN PESILKKAYL ESFTIDLDYR EFLDDALDEN WELRQELENE SQDKWWIVKP 480
  481 SMSDKGQGIR VFKTIEDLQA IFDSFDDEDS EAEESGNDDD ADDVNGEFMD NNKVNISQLR 540
  541 HFIIQEYLTN PLLLASMDNR KFHIRCYVVC RGDLQVFVYD RMLALFAAKP FVPLDPYAYS 600
  601 VTDLKDLECH LTNTCLQSKK KDKDSSVLEF DSIEEIPNER KSNIKEQIHS ITNDVFLAAV 660
  661 NVNRLNFQPL PNAFETYGVD FLIDSNYEVK LLEINAFPDF KQTGKDLKNL IDELFDDTVK 720
  721 YCVTPIFNEN RNKTDDETDP NFVKVIDYTS NGW

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) EDC3 PBY1
    View Details Krogan NJ, et al. (2006) DCP1 DCP2 EDC2 EDC3 PBY1
    View Details Ho Y, et al. (2002) CKA2 PBY1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PBY1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..241] PSI-BLAST 100.69897 SurE homolog TM1662
    2 View Details [242..374] deduced N/A No confident structure predictions are available.
    3 View Details [375..753] Pfam 114.69897 Tubulin-tyrosine ligase family No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle