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View Structure Prediction Details

Protein: PBY1
Organism: Saccharomyces cerevisiae
Length: 753 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PBY1.

Description E-value Query
Range
Subject
Range
PBY1 - Putative tubulin tyrosine ligase associated with P-bodies
0.0 [1..753] [1..753]
gi|21492624, gi|... - gi|21492624|ref|NP_083340.1| tubulin tyrosine ligase like family 9 [Mus musculus], gi|12854186|dbj|B...
2.0E-99 [361..722] [37..390]
gi|114686762, gi... - gi|114686764|ref|XP_001171655.1| PREDICTED: tubulin tyrosine ligase-like family, member 1 isoform 6 ...
gi|123982766, gi... - gi|123997435|gb|ABM86319.1| tubulin tyrosine ligase-like family, member 1 [synthetic construct], gi|...
HGNC:1312|MIM:60... - tyrosine ligase-like family, member 1
TTLL1 - tubulin tyrosine ligase-like family, member 1
6.0E-96 [359..747] [12..383]
CG32238-PA - This gene is referred to in FlyBase by the symbol Dmel\CG32238 (CG32238, FBgn0052238). It is a prote...
5.0E-90 [358..747] [82..458]
SPAC12B10.04 - tubulin-tyrosine ligase
TTL_SCHPO - Probable tubulin--tyrosine ligase C12B10.04 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...
3.0E-84 [370..739] [36..391]
gi|27311791, gi|... - gi|30984528|gb|AAP42727.1| At4g14930 [Arabidopsis thaliana], gi|27311791|gb|AAO00861.1| expressed pr...
5.0E-81 [3..308] [16..286]

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Predicted Domain #1
Region A:
Residues: [1-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVLITNDDG PLSDQFSPYI RPFIQHIKRN YPEWKITVCV PHVQKSWVGK AHLAGKNLTA  60
   61 QFIYSKVDAE DNTFWGPFIQ PQIRSENSKL PYVLNAEIPK DTIEWILIDG TPASCANIGL 120
  121 HLLSNEPFDL VLSGPNVGRN TSAAYITSSG TVGGAMESVI TGNTKAIAIS WAYFNGLKNV 180
  181 SPLLMEKASK RSLDVIKHLV KNWDPKTDLY SINIPLVESL SDDTKVYYAP IWENRWIPIF 240
  241 N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 100.69897
Match: 1j9jA_
Description: SurE homolog TM1662
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [242-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPHINLENSF AEIEDGNESS SISFNWAPKF GAHKDSIHYM DEYKDRTVLT DAEVIESEMI  60
   61 SVTPMKATFK GVNHLLGELK LTEEENNLSK TNNLIVVSID PMEYIYKPLT HALKKYLPQV 120
  121 EIVSNLPEFD NGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [375-753]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CEKEMKVFHY GDYEQLDMDK LMELPNNYFT NSYIYRKALI RKHFLSHTIQ TYTAKNPESI  60
   61 LKKAYLESFT IDLDYREFLD DALDENWELR QELENESQDK WWIVKPSMSD KGQGIRVFKT 120
  121 IEDLQAIFDS FDDEDSEAEE SGNDDDADDV NGEFMDNNKV NISQLRHFII QEYLTNPLLL 180
  181 ASMDNRKFHI RCYVVCRGDL QVFVYDRMLA LFAAKPFVPL DPYAYSVTDL KDLECHLTNT 240
  241 CLQSKKKDKD SSVLEFDSIE EIPNERKSNI KEQIHSITND VFLAAVNVNR LNFQPLPNAF 300
  301 ETYGVDFLID SNYEVKLLEI NAFPDFKQTG KDLKNLIDEL FDDTVKYCVT PIFNENRNKT 360
  361 DDETDPNFVK VIDYTSNGW

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 114.69897
Match: PF03133
Description: Tubulin-tyrosine ligase family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle