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Protein Overview: ALG3

General Information:
Name(s) found: ALG3 / YBL082C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Dolichol-P-Man dependent alpha(1-3) mannosyltransferase, involved in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 458 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IMPLink to PubMed article][ISSLink to PubMed article]
    Biological Process: protein amino acid glycosylation [IMPLink to PubMed article]
    dolichol-linked oligosaccharide biosynthetic process [TASLink to PubMed article]
    Molecular Function: alpha-1,3-mannosyltransferase activity [IDALink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGEQSPQGE KSLQRKQFVR PPLDLWQDLK DGVRYVIFDC RANLIVMPLL ILFESMLCKI  60
   61 IIKKVAYTEI DYKAYMEQIE MIQLDGMLDY SQVSGGTGPL VYPAGHVLIY KMMYWLTEGM 120
  121 DHVERGQVFF RYLYLLTLAL QMACYYLLHL PPWCVVLACL SKRLHSIYVL RLFNDCFTTL 180
  181 FMVVTVLGAI VASRCHQRPK LKKSLALVIS ATYSMAVSIK MNALLYFPAM MISLFILNDA 240
  241 NVILTLLDLV AMIAWQVAVA VPFLRSFPQQ YLHCAFNFGR KFMYQWSINW QMMDEEAFND 300
  301 KRFHLALLIS HLIALTTLFV TRYPRILPDL WSSLCHPLRK NAVLNANPAK TIPFVLIASN 360
  361 FIGVLFSRSL HYQFLSWYHW TLPILIFWSG MPFFVGPIWY VLHEWCWNSY PPNSQASTLL 420
  421 LALNTVLLLL LALTQLSGSV ALAKSHLRTT SSMEKKLN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ALG3 BUD27 CBF2 DST1 ESS1 IWR1 RPB10 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPO21 RPO26 SPT4 TAF14 TFG1 TFG2 YBL059W YBR259W YPL225W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ALG3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..346] MSA 2.010915 View MSA. No confident structure predictions are available.
    2 View Details [347..458] MSA 1.008973 View MSA. Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle