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Protein Overview: JMJD6_RAT

General Information:
Name(s) found: JMJD6_RAT [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 OS=Rattus norvegicus GN=Jmjd6 PE=2 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 403 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][ISS]
    cellular_component [ND]
    plasma membrane [UNKNOWN]
    Biological Process: chromatin modification [IEA]
    biological_process [ND]
    RNA splicing [IEA]
    multicellular organismal development [IEA]
    T cell differentiation in the thymus [UNKNOWN]
    retina development in camera-type eye [UNKNOWN]
    apoptotic cell clearance [UNKNOWN]
    cell surface receptor linked signaling pathway [UNKNOWN]
    erythrocyte development [UNKNOWN]
    mRNA processing [IEA]
    regulation of transcription [IEA]
    recognition of apoptotic cell [UNKNOWN]
    macrophage activation [UNKNOWN]
    heart development [UNKNOWN]
    blood vessel development [UNKNOWN]
    histone H3-R2 demethylation [UNKNOWN]
    kidney development [UNKNOWN]
    histone H4-R3 demethylation [UNKNOWN]
    apoptosis [UNKNOWN]
    peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [UNKNOWN][ISS]
    regulation of nuclear mRNA splicing, via spliceosome [UNKNOWN]
    cell differentiation [IEA]
    oxidation reduction [IEA]
    lung development [UNKNOWN]
    Molecular Function: histone demethylase activity (H4-R3 specific) [UNKNOWN][ISS]
    oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [IEA]
    identical protein binding [UNKNOWN]
    protein binding [UNKNOWN]
    peptidyl-lysine 5-dioxygenase activity [UNKNOWN][ISS]
    oxidoreductase activity [IEA]
    metal ion binding [IEA]
    receptor activity [UNKNOWN]
    histone demethylase activity (H3-R2 specific) [UNKNOWN][ISS]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNHKSKKRIR EAKRSARPEL KDSLDWTRHN YYESYPLSPA AVPDNVERAD ALQLSVKEFV  60
   61 ERYERPYKPV VLLNAQEGWS AQEKWTLERL KRKYRNQKFK CGEDNDGYSV KMKMKYYIEY 120
  121 MESTRDDSPL YIFDSSYGEH PKRRKLLEDY KVPKFFTDDL FQYAGEKRRP PYRWFVMGPP 180
  181 RSGTGIHIDP LGTSAWNALV QGHKRWCLFP TNTPRELIKV TREEGGNQQD EAITWFNVIY 240
  241 PRTQLPTWPP EFKPLEILQK PGETVFVPGG WWHVVLNLDT TIAITQNFAS STNFPVVWHK 300
  301 TVRGRPKLSR KWYRILKQEH PELAVLADAV DLQESTGIAS DSSSDSSSSS SSSSSDSDSE 360
  361 CESGSEGDGT THRRKKRRTC SMVGNGDTTS QDDCVSKERS SSR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle