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A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. Any process that stimulates, induces or increases the rate of macrophage activation. A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. Any process that stops, prevents or reduces the frequency, rate or extent of macrophage activation. Any process that modulates the frequency or rate of macrophage activation. The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: macrophage activation
Acc: GO:0042116
Aspect: Biological Process
Desc: A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
Proteins in PDR annotated with:
   This term: 15 [Search]
   Term or descendants: 59 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042116 - macrophage activation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle