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Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor. Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: peptidyl-lysine 5-dioxygenase activity
Acc: GO:0070815
Aspect: Molecular Function
Desc: Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2.
Synonyms:
  • lysine hydroxylase activity
  • lysyl hydroxylase activity
  • peptide-lysine 5-dioxygenase activity
  • peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase activity
  • peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity
  • protein lysine hydroxylase activity
  • lysine,2-oxoglutarate 5-dioxygenase activity
  • lysine-2-oxoglutarate dioxygenase activity
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 12 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070815 - peptidyl-lysine 5-dioxygenase activity (interactive image map)
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