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Protein Overview: STY8_ARATH

General Information:
Name(s) found: STY8_ARATH [Swiss-Prot]
Description(s) found:
Found 12 descriptions.
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  • Serine/threonine-protein kinase STY8 OS=Arabidopsis thaliana GN=STY8 PE=1 SV=2 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 546 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDA]
    Biological Process: metabolic process [IEA]
    protein amino acid phosphorylation [IEA]
    Molecular Function: protein serine/threonine/tyrosine kinase activity [ISS]
    protein kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIKDESESC GSRAVVASPS QENPRHYRMK LDVYSEVLQR LQESNYEEAT LPDFEDQLWL  60
   61 HFNRLPARYA LDVKVERAED VLTHQRLLKL AADPATRPVF EVRSVQVSPR ISADSDPAVE 120
  121 EDAQSSHQPS GPGVLAPPTF GSSPNFEAIT QGSKIVEDVD SVVNATLSTR PMHEITFSTI 180
  181 DKPKLLSQLT SLLGELGLNI QEAHAFSTVD GFSLDVFVVD GWSQEETDGL RDALSKEILK 240
  241 LKDQPGSKQK SISFFEHDKS SNELIPACIE IPTDGTDEWE IDVTQLKIEK KVASGSYGDL 300
  301 HRGTYCSQEV AIKFLKPDRV NNEMLREFSQ EVFIMRKVRH KNVVQFLGAC TRSPTLCIVT 360
  361 EFMARGSIYD FLHKQKCAFK LQTLLKVALD VAKGMSYLHQ NNIIHRDLKT ANLLMDEHGL 420
  421 VKVADFGVAR VQIESGVMTA ETGTYRWMAP EVIEHKPYNH KADVFSYAIV LWELLTGDIP 480
  481 YAFLTPLQAA VGVVQKGLRP KIPKKTHPKV KGLLERCWHQ DPEQRPLFEE IIEMLQQIMK 540
  541 EVNVVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..113] PSI-BLAST 40.69897 Crystal Structure of the 3 Ig form of FGFR3c in complex with FGF1
    2 View Details [114..546] PSI-BLAST 92.154902 CHICKEN SRC TYROSINE KINASE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor activity
    		•  3.43161288468336 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  3.21639072755286 bayes_pls_golite062009
  • binding
    		•  3.17641566810715 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.65769780435188 bayes_pls_golite062009
  • signal transducer activity
    		•  2.65769780435188 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  1.89129472744944 bayes_pls_golite062009
  • antigen binding
    		•  1.63189745559168 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  1.52958974617075 bayes_pls_golite062009
  • protein kinase activity
    		•  1.36635494500222 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  1.30657787244536 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
    		•  1.24730237107473 bayes_pls_golite062009
  • growth factor binding
    		•  1.21242049144353 bayes_pls_golite062009
  • protein binding
    		•  1.17809977833322 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.02286631988334 bayes_pls_golite062009
  • kinase activity
    		•  0.929878054374821 bayes_pls_golite062009
  • receptor binding
    		•  0.909733688848793 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.878595022643164 bayes_pls_golite062009
  • protein complex binding
    		•  0.83543827718565 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.564762108830441 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.518011841154552 bayes_pls_golite062009
  • peptide antigen binding
    		•  0.42715742534369 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.38670960441694 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  0.318890055375093 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.316848380982695 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  0.313212481552211 bayes_pls_golite062009
  • DNA binding
    		•  0.304320681250924 bayes_pls_golite062009
  • peptide binding
    		•  0.287592562640369 bayes_pls_golite062009
  • actin binding
    		•  0.18356099709255 bayes_pls_golite062009
  • fibroblast growth factor binding
    		•  0.0972287515196089 bayes_pls_golite062009
  • transferase activity
    		•  0.053007146193305 bayes_pls_golite062009
    2
    Term Confidence Notes
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.04467222534257 bayes_pls_golite062009
  • kinase activity
    		•  4.85903980916957 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.63692708178478 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  3.41480681854114 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  3.40140621607334 bayes_pls_golite062009
  • transferase activity
    		•  3.26787750561728 bayes_pls_golite062009
  • epidermal growth factor receptor binding
    		•  2.9751846707539 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  2.8153155526437 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  2.59526003830791 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • signal transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • receptor activity
    		•  2.39311927684508 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  2.10379226653669 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.81249386965144 bayes_pls_golite062009
  • molecular adaptor activity
    		•  1.81145713371725 bayes_pls_golite062009
  • non-membrane spanning protein tyrosine kinase activity
    		•  1.66669268613198 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • vinculin binding
    		•  1.63216315345235 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • SH3/SH2 adaptor activity
    		•  1.59474164216385 bayes_pls_golite062009
  • growth factor binding
    		•  1.53863828216563 bayes_pls_golite062009
  • protein binding
    		•  1.22565748038754 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase activity
    		•  1.10045286406485 bayes_pls_golite062009
  • transforming growth factor beta receptor activity
    		•  1.10045286406485 bayes_pls_golite062009
  • protein binding, bridging
    		•  0.83823250804321 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.81943579965027 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
    		•  0.75189004129952 bayes_pls_golite062009
  • insulin receptor substrate binding
    		•  0.74324450025139 bayes_pls_golite062009
  • transporter activity
    		•  0.710766490066447 bayes_pls_golite062009
  • insulin receptor activity
    		•  0.692904214601 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  0.610230065465794 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.60324822483033 bayes_pls_golite062009
  • activin binding
    		•  0.510364757301021 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.499492353295369 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.385603245903806 bayes_pls_golite062009
  • PTB domain binding
    		•  0.372700602565411 bayes_pls_golite062009
  • JUN kinase kinase kinase kinase activity
    		•  0.349343975617553 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
    		•  0.33808087202461 bayes_pls_golite062009
  • insulin binding
    		•  0.326213234151689 bayes_pls_golite062009
  • kinase binding
    		•  0.26752427107238 bayes_pls_golite062009
  • protein complex binding
    		•  0.239339759110451 bayes_pls_golite062009
  • receptor binding
    		•  0.197402253061255 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.152203945257581 bayes_pls_golite062009
  • transforming growth factor beta receptor activity, type I
    		•  0.0506751594607393 bayes_pls_golite062009
  • protein kinase binding
    		•  0.00674998152095019 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle