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Protein Overview: gi|30262788, gi|...

General Information:
Name(s) found: gi|30262788 [NCBI NR]
gi|30257420 [NCBI NR]
Description(s) found:
Found 4 descriptions.
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  • gi|30262788|ref|NP_845165.1| ATP-dependent DNA helicase RecQ [Bacillus anthracis str. Ames] [NCBI NR]
  • gi|30257420|gb|AAP26651.1| ATP-dependent DNA helicase RecQ [Bacillus anthracis str. Ames] [NCBI NR]
    • Organism: Bacillus anthracis str. Ames
    Length: 705 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: DNA repair [ISSLink to PubMed article]
    DNA recombination [ISSLink to PubMed article]
    DNA unwinding involved in replication [ISSLink to PubMed article]
    Molecular Function: four-way junction helicase activity [ISSLink to PubMed article]
    ATP-dependent DNA helicase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFTKAQELLA SYFGYSSFRR GQDETIKNVL DGKDTVCIMP TGGGKSICYQ IPALVFEGTT  60
   61 LVISPLISLM KDQVDTLVQN GISATYINSS ISITEANQRI QLAKQGHYKL FYVAPERLDS 120
  121 MEFVDQLIDM KIPMIAIDEA HCISQWGHDF RPSYLHIHRI LDYLPEEPLV LALTATATPQ 180
  181 VRDDICNTLG INQENTIMTT FERENLSFSV IKGQDRNAYL ADYIRQNQKE SGIIYAATRK 240
  241 VVDQLYEDLM KAGVSVSKYH AGMSDHDRNE QQELFLRDEV SVMVATSAFG MGIDKSNIRY 300
  301 VIHYQLPKNM ESYYQEAGRA GRDGLDSACI LLYASQDVQV QRFLIDQSIG ESRFSNELEK 360
  361 LQNMTDYCHT EQCLQSFILQ YFGEEPKEDC GRCGNCTDNR ESIDVTRESQ MVLSCMIRTN 420
  421 QRFGKQMIAQ VLTGSKNKKV IEFNFHTLPT YGLLSNRSVK EVSEFIEFLI SDELIAVEHG 480
  481 TYPTLKVTEK GKEVLLGKEN VLRKERVETR QIVQDHPLFE VLREVRKEIA QGEGVPPFVI 540
  541 FSDQTLKDMC AKMPQSDSEL LTVKGIGEHK LVKYGSHFLQ AVQHFIEENP NYAETIKTEV 600
  601 VSERKKSGKA SANSHLETYE MYKQGIDLDE IAKERGLSRQ TIENHLIRCF EDGMEVDWNS 660
  661 FVPAEYEQLI ETAVQNAEGG LKSIKEQLPN EVSYFMIRAY LQIRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..505] PSI-BLAST 92.522879 Structure of the RecQ Catalytic Core
    2 View Details [506..705] PSI-BLAST 22.0 nucleosome recognition module of ISWI ATPase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  7.79457008386475 bayes_pls_golite062009
  • DNA helicase activity
    		•  5.33108843895592 bayes_pls_golite062009
  • four-way junction helicase activity
    		•  5.20361383647271 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  4.98637553020315 bayes_pls_golite062009
  • translation regulator activity
    		•  4.94658029227343 bayes_pls_golite062009
  • single-stranded DNA-dependent ATPase activity
    		•  3.37733874794175 bayes_pls_golite062009
  • RNA cap binding
    		•  3.05696024978364 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.13284212711072 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.11222585187695 bayes_pls_golite062009
  • DNA binding
    		•  1.7904783386531 bayes_pls_golite062009
  • helicase activity
    		•  1.70242731830224 bayes_pls_golite062009
  • single-stranded DNA-dependent ATP-dependent DNA helicase activity
    		•  1.69315154404254 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.68903321260301 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  1.54436515966471 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  1.51134988628578 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.47858140861683 bayes_pls_golite062009
  • RNA helicase activity
    		•  1.42791449104435 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  1.39335733374328 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  1.36724390116598 bayes_pls_golite062009
  • microtubule motor activity
    		•  1.30090199952739 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.2539059700735 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.2155186842031 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  1.117585097627 bayes_pls_golite062009
  • motor activity
    		•  1.03253378953548 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.971476020912368 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.928091843881235 bayes_pls_golite062009
  • structural molecule activity
    		•  0.86514677273731 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.607045223341107 bayes_pls_golite062009
  • transcription factor activity
    		•  0.603758349693077 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.5886142102548 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.569910969126728 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.568840867400671 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.568779924702229 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.568457189190858 bayes_pls_golite062009
  • nucleotide binding
    		•  0.564275755355315 bayes_pls_golite062009
    		• 0.442119153778711 bayes_pls_golite062009
  • mismatched DNA binding
    		•  0.31144582840038 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.2184107989371 bayes_pls_golite062009
  • ATP binding
    		•  0.1860481660648 bayes_pls_golite062009
  • exodeoxyribonuclease V activity
    		•  0.185603938981231 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.152859582615242 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.147579541298736 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.138615225841109 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.113504049290503 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.111293884322157 bayes_pls_golite062009
  • RNA binding
    		•  0.0261282189186349 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle