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Protein Overview: gi|30256828, gi|...

General Information:
Name(s) found: gi|30262197 [NCBI NR]
gi|30256828 [NCBI NR]
Description(s) found:
Found 4 descriptions.
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  • gi|30262197|ref|NP_844574.1| isoleucyl-tRNA synthetase [Bacillus anthracis str. Ames] [NCBI NR]
  • gi|30256828|gb|AAP26060.1| isoleucyl-tRNA synthetase [Bacillus anthracis str. Ames] [NCBI NR]
    • Organism: Bacillus anthracis str. Ames
    Length: 1033 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: isoleucyl-tRNA aminoacylation [ISSLink to PubMed article]
    Molecular Function: isoleucine-tRNA ligase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKVDVKESA VGREMRIRKQ WNEQNIFEQS IQNREGAQSF VFYEGPPTAN GLPHVGHALG  60
   61 RTIKDVVARY KTMAGYKVLR KAGWDTHGLP VELGVEKQLG ISGKHEIEEY GIEPFIKKCK 120
  121 ESVFTYEKQW REFTESIGYW VDMDDPYVTL ENPYIESVWH ILGTIHEKGL LYKGHRVSPY 180
  181 CPSCQTSLSS HEVAQGYKTV KDLSATVKFK VKDSENEYFL GWTTTPWTLP ANVALAVHPN 240
  241 MEYVKAKQEG HVYIVAKERV QDVLKENYEV LSVHKGEELL NISYTAPFPM KEVTNGYRVI 300
  301 GADFVTADSG TGLVHIAPAY GEDDYRVVQS EGLSFLHVVD EKGEYTEAVP FLKGKFVKDC 360
  361 DVDIVRYLAK EDLLYHKEKY EHSYPHCWRC DSPLLYYAGE SWLIRTTAIK DTFLQNNDTV 420
  421 TWYPDHMKHG RFGKFLENMV DWNISRNRYW GTPLNVWECE RCDHQFAPKS IADLRKHSMK 480
  481 ETPEDLELHK PYVDEVQVCC EKCGSTMNRT PEVIDVWFDS GSMPFAQYHY PFENKELFEE 540
  541 QFPADVIAEG IDQTRGWFYS LLAVSALYTG KVPYKRVLSL GHVLDEEGQK MSKSKGNALD 600
  601 PVDLVGKFGA DALRWALLVD SALWNAKRFS ERTVLEAKSK FVDTLVNVYS FYVLYANLDE 660
  661 YNPNETYDVK RTKLDEWVLS RLHSTTKKVR TALDDYQFTN AAREIAALVD EVSNWYVRRS 720
  721 RNRFWESGMN AEKAAAYETL HDVLVTISKL IAPFTPFVAE DVHLNLTGSS VHLEDYPVVN 780
  781 ESLLQPKLEA EMDAVLQVVE LGRSNRNQHS LKVKQPLAEL VLLEHNENDM DWESYRDIVM 840
  841 DELNVKAFHV ELDETKYTSY QLKLNFKKAG PKFGKNVNAV NGWLKQLSQD EVQNFVSTER 900
  901 AVYEVAPGEE IVVTTEDVLV EKVAKSGFSN TTNGQYTVML DTNVTEELLQ EGVAREFIRA 960
  961 VQEYRKQLNL PVNLRVDVIL DTEEELQQTL TNHKELLEEN LLVKQFTFGH LTNEDDELSL1020
 1021 GETKVRIKLS TAQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..811] PSI-BLAST 1000.0 ISOLEUCYL-TRNA SYNTHETASE
    2 View Details [812..925] PSI-BLAST 49.522879 Methionyl-tRNA synthetase from Pyrococcus abyssi
    3 View Details [926..1033] FFAS03 1.1 X-RAY STRUCTURE OF GENE PRODUCT FROM ARABIDOPSIS THALIANA AT1G77540

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • valine-tRNA ligase activity
    		•  7.13767629265822 bayes_pls_golite062009
  • leucine-tRNA ligase activity
    		•  7.03538514482698 bayes_pls_golite062009
  • isoleucine-tRNA ligase activity
    		•  6.38633897147986 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.01261843164558 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.13743634264647 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • binding
    		•  0.27454602748467 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.2293846471193 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.161799496958314 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • transferase activity
    		•  2.11244007360413 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  1.94638590323545 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  1.83027840181539 bayes_pls_golite062009
  • catalytic activity
    		•  1.823104805379 bayes_pls_golite062009
  • acyltransferase activity
    		•  1.79975330506106 bayes_pls_golite062009
  • acetyltransferase activity
    		•  0.982158175405503 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  0.95277111277247 bayes_pls_golite062009
  • binding
    		•  0.465197530725468 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.255991112435493 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.11900800706558 bayes_pls_golite062009
  • protein binding
    		•  0.0165329419157162 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  0.00126652056286969 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  0.00126652056286969 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle