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Protein Overview: MDH_SHEON

General Information:
Name(s) found: MDH_SHEON [Swiss-Prot]
Description(s) found:
Found 5 descriptions.
SHOW ALL
  • Malate dehydrogenase OS=Shewanella oneidensis (strain MR-1) GN=mdh PE=1 SV=2 [Swiss-Prot]
    • Organism: Shewanella oneidensis MR-1
    Length: 311 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: tricarboxylic acid cycle [ISSLink to PubMed article]
    Molecular Function: malate dehydrogenase activity [ISSLink to PubMed article]
    malic enzyme activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVAVLGAAG GIGQALALLL KTQLPAGSKL SLYDIAPVTP GVAVDLSHIP TAVEIKGFAG  60
   61 EDPTPALVGA DVVLISAGVA RKPGMDRSDL FNINAGIVRN LIEKVAVTCP KALVGIITNP 120
  121 VNTTVAIAAE VMKKAGVYDK NRLFGVTTLD VIRSETFIAE LKGLNVADVK INVIGGHSGV 180
  181 TILPLLSQVE GVTFSDEEVA SLTKRIQNAG TEVVEAKAGG GSATLSMGQA ACRFGMSLVR 240
  241 GLQGEANVVE CAYVDGGSEH AEFFAQPVLL GKNGIEKVLP YGEVSAFEAN ARDSMLDTLK 300
  301 GDIKLGVDFV K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..311] PSI-BLAST 82.522879 No description for 2pwzA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • malate dehydrogenase activity
    		•  4.38786524125089 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.09625241707629 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  3.06391460989761 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  3.02758902218302 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  2.94416173750168 bayes_pls_golite062009
  • L-lactate dehydrogenase activity
    		•  2.59062377380589 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  2.26153457113968 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • lactate dehydrogenase activity
    		•  1.72858895767068 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  1.70038641098437 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.65338499044318 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47309297191111 bayes_pls_golite062009
  • malic enzyme activity
    		•  1.2147813077436 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  1.16811519855038 bayes_pls_golite062009
  • L-malate dehydrogenase activity
    		•  1.02646414923682 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  0.99118526697655 bayes_pls_golite062009
  • transporter activity
    		•  0.793769336118517 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.788034697021177 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.635891484075352 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.576163737662951 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.516630524306975 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.44922383360529 bayes_pls_golite062009
  • enoyl-CoA hydratase activity
    		•  0.439912268968251 bayes_pls_golite062009
  • coenzyme binding
    		•  0.35922330382799 bayes_pls_golite062009
  • binding
    		•  0.355184540089764 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.300373102236296 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.239024094835991 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  0.216422278300306 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.165260811069909 bayes_pls_golite062009
  • NADPH:quinone reductase activity
    		•  0.136079082491021 bayes_pls_golite062009
  • malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity
    		•  0.120195861875768 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  0.0962368786590111 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.0257250793986203 bayes_pls_golite062009
  • glyoxylate reductase activity
    		•  0.0221984076575323 bayes_pls_golite062009
  • formate dehydrogenase activity
    		•  4.92199819939532E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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