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Catalysis of the reaction: (R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c. Catalysis of the oxidation of lactate to produce pyruvate. Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+. Catalysis of the reaction: (R)-lactate + NAD+ = pyruvate + NADH + H+. Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c. Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: lactate dehydrogenase activity
Acc: GO:0004457
Aspect: Molecular Function
Desc: Catalysis of the oxidation of lactate to produce pyruvate.
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 43 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004457 - lactate dehydrogenase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle