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Protein Overview: SWR1_YEAST

General Information:
Name(s) found: SWR1_YEAST [Swiss-Prot]
Description(s) found:
  • Helicase SWR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SWR1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1514 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTSRKSHAK DKKAGGEQDL ADLKFRYDLL TNELFHLREF VSLVDYDPTH FNDSESFQKF  60
   61 LRETHLSLEE RGEKFTDDVA KKGTNGDLTR RRRNLRTSTV VSSETTNEKK GDIELKLESI 120
  121 APLVRNKCEE LKYKLSDHSN RKSIVPQKRP IQHLKKREAA KSLKFKSERK ENPLPLHEHI 180
  181 AEERYDHIAK VEEPSEAFTI KCPSDDSSFE NTSEHYSDNF YFTTSSEEED IKKKRGRKKK 240
  241 KPRIKLVVHP PKQTITNPLH VVKPGYESLH EYIASFKSLE DDLTLEEYNK YIDEQRRLLS 300
  301 RLKKGIENGA LKYDKETDSL QPITSKEIKT IITYKPDPIS YFYKQQDLQI HTDHLINQGI 360
  361 HMSKLFRSST KARIARAKKV SQMIEQHFKH VAGAEERKAK EEERHKKSLA RFAVQAVKKR 420
  421 WNMAEKAYRI LRKDEEEQLK RIEGKQHLSK MLEKSTQLLE AQLNQVNDDG RSSTPSSDSN 480
  481 DVLSESDDDM DDELSTSSDE DEEVDADVGL ENSPASTEAT PTDESLNLIQ LKEKYGHFNG 540
  541 SSTVYDSRNK DEKFPTLDKH ESSSSESSVM TGEESSIYSS SENESQNEND RESDDKTPSV 600
  601 GLSALFGKGE ESDGDLDLDD SEDFTVNSSS VEGEELEKDQ VDNSAATFER AGDFVHTQNE 660
  661 NRDDIKDVEE DAETKVQEEQ LSVVDVPVPS LLRGNLRTYQ KQGLNWLASL YNNHTNGILA 720
  721 DEMGLGKTIQ TISLLAYLAC EKENWGPHLI VVPTSVLLNW EMEFKRFAPG FKVLTYYGSP 780
  781 QQRKEKRKGW NKPDAFHVCI VSYQLVVQDQ HSFKRKRWQY MVLDEAHNIK NFRSTRWQAL 840
  841 LNFNTQRRLL LTGTPLQNNL AELWSLLYFL MPQTVIDGKK VSGFADLDAF QQWFGRPVDK 900
  901 IIETGQNFGQ DKETKKTVAK LHQVLRPYLL RRLKADVEKQ MPAKYEHIVY CKLSKRQRFL 960
  961 YDDFMSRAQT KATLASGNFM SIVNCLMQLR KVCNHPNLFE VRPILTSFVL EHCVASDYKD1020
 1021 VERTLLKLFK KNNQVNRVDL DFLNLVFTLN DKDLTSYHAE EISKLTCVKN FVEEVNKLRE1080
 1081 TNKQLQEEFG EASFLNFQDA NQYFKYSNKQ KLEGTVDMLN FLKMVNKLRC DRRPIFGKNL1140
 1141 IDLLTKDRRV KYDKSSIIDN ELIKPLQTRV LDNRKIIDTF AVLTPSAVSL DMRKLALGLN1200
 1201 DDSSVGENTR LKVMQNCFEV SNPLHQLQTK LTIAFPDKSL LQYDCGKLQK LAILLQQLKD1260
 1261 NGHRALIFTQ MTKVLDVLEQ FLNYHGYLYM RLDGATKIED RQILTERFNT DSRITVFILS1320
 1321 SRSGGLGINL TGADTVIFYD SDWNPAMDKQ CQDRCHRIGQ TRDVHIYRFV SEHTIESNIL1380
 1381 KKANQKRQLD NVVIQEGDFT TDYFSKLSVR DLLGSELPEN ASGGDKPLIA DADVAAKDPR1440
 1441 QLERLLAQAE DEDDVKAANL AMREVEIDND DFDESTEKKA ANEEEENHAE LDEYEGTAHV1500
 1501 DEYMIRFIAN GYYY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..346] PSI-BLAST 3.154902 Heavy meromyosin subfragment
    2 View Details [347..632] deduced N/A No confident structure predictions are available.
    3 View Details [633..1005] Pfam 114.004365 SNF2 family N-terminal domain No confident structure predictions are available.
    4 View Details [1006..1237] deduced N/A No confident structure predictions are available.
    5 View Details [1238..1360] Pfam 22.031517 Helicase conserved C-terminal domain No confident structure predictions are available.
    6 View Details [1361..1514] MSA 4.202995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.68677407235528 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.55499128961037 bayes_pls_golite062009
  • telomeric DNA binding
    		•  2.51555240517937 bayes_pls_golite062009
  • single-stranded telomeric DNA binding
    		•  2.42617682290608 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.05166830102408 bayes_pls_golite062009
  • structural molecule activity
    		•  1.88289765635623 bayes_pls_golite062009
  • DNA binding
    		•  1.82124247082886 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.44779598506198 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.29444332911502 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.28974640221593 bayes_pls_golite062009
  • hydrolase activity
    		•  0.724860465280978 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.498105565279986 bayes_pls_golite062009
  • translation regulator activity
    		•  0.433181719163502 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.385829426544547 bayes_pls_golite062009
  • protein binding
    		•  0.360033745054291 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.249698955842391 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.227933240776321 bayes_pls_golite062009
  • chromatin binding
    		•  0.1876135725713 bayes_pls_golite062009
  • nuclease activity
    		•  0.1667307589287 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.12942560136182 bayes_pls_golite062009
  • telomerase inhibitor activity
    		•  0.111973370145519 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.0926650185896696 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.0926650185896696 bayes_pls_golite062009
    4
    Term Confidence Notes
  • DNA-dependent ATPase activity
    		•  2.58390156971125 bayes_pls_golite062009
  • hydrolase activity
    		•  2.55157966585974 bayes_pls_golite062009
  • binding
    		•  2.4974940028864 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.85030653553169 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.84811666933472 bayes_pls_golite062009
  • motor activity
    		•  1.14667913749579 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.0904709750093 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  1.05990253628867 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  1.05990253628867 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.775560967092349 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.60036517876321 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.540750418412449 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.517457589081898 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.500462538667228 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.428373955572763 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.424644011903671 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.424583288440993 bayes_pls_golite062009
  • nucleotide binding
    		•  0.422354428195324 bayes_pls_golite062009
  • protein binding
    		•  0.378225828131122 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.3665939534705 bayes_pls_golite062009
  • helicase activity
    		•  0.243380876721902 bayes_pls_golite062009
  • DNA binding
    		•  0.226110787229935 bayes_pls_golite062009
  • ATP binding
    		•  0.04834397972685 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.0315266818880198 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.0149501427627318 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.0102645529518819 bayes_pls_golite062009
  • actin binding
    		•  0.00482938540552702 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.00365326483311895 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle