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Protein Overview: C85A2_ARATH

General Information:
Name(s) found: C85A2_ARATH [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
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  • Cytochrome P450 85A2 OS=Arabidopsis thaliana GN=CYP85A2 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 465 amino acids

    Gene Ontology:
    Cellular Component: endomembrane system [IEA]
    Biological Process: brassinosteroid biosynthetic process [IDA]
    Molecular Function: oxygen binding [ISS]
    monooxygenase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIMMMILGL LVIIVCLCTA LLRWNQMRYS KKGLPPGTMG WPIFGETTEF LKQGPDFMKN  60
   61 QRLRYGSFFK SHILGCPTIV SMDAELNRYI LMNESKGLVA GYPQSMLDIL GTCNIAAVHG 120
  121 PSHRLMRGSL LSLISPTMMK DHLLPKIDDF MRNYLCGWDD LETVDIQEKT KHMAFLSSLL 180
  181 QIAETLKKPE VEEYRTEFFK LVVGTLSVPI DIPGTNYRSG VQARNNIDRL LTELMQERKE 240
  241 SGETFTDMLG YLMKKEDNRY LLTDKEIRDQ VVTILYSGYE TVSTTSMMAL KYLHDHPKAL 300
  301 EELRREHLAI RERKRPDEPL TLDDIKSMKF TRAVIFETSR LATIVNGVLR KTTHDLELNG 360
  361 YLIPKGWRIY VYTREINYDT SLYEDPMIFN PWRWMEKSLE SKSYFLLFGG GVRLCPGKEL 420
  421 GISEVSSFLH YFVTKYRWEE NGEDKLMVFP RVSAPKGYHL KCSPY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..465] PSI-BLAST 89.045757 Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arachidonic acid monooxygenase activity
    		•  6.76823710927794 bayes_pls_golite062009
  • monooxygenase activity
    		•  5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  5.04794778387361 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  5.03099580095037 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  4.80764258881036 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  3.76307535769621 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.68151610133025 bayes_pls_golite062009
  • demethylase activity
    		•  3.40807632433846 bayes_pls_golite062009
  • retinoic acid binding
    		•  3.04897926497756 bayes_pls_golite062009
  • sterol 14-demethylase activity
    		•  2.94610675710811 bayes_pls_golite062009
  • retinoid binding
    		•  2.60220937953757 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.55570471815523 bayes_pls_golite062009
  • isoprenoid binding
    		•  2.47826119804163 bayes_pls_golite062009
  • steroid 7-alpha-hydroxylase activity
    		•  2.29989218606587 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.09151585300316 bayes_pls_golite062009
  • oxygen binding
    		•  1.66120675703571 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  1.65569090470706 bayes_pls_golite062009
  • electron carrier activity
    		•  1.48516712188486 bayes_pls_golite062009
  • binding
    		•  1.2866152532988 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
    		•  0.918503562996019 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  0.33710488712754 bayes_pls_golite062009
  • 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
    		•  0.169431271735966 bayes_pls_golite062009
  • arachidonic acid 11,12-epoxygenase activity
    		•  0.0888154993183798 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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