Protein Overview: gi|208966364

General Information:
Name(s) found:	gi\|208966364 [NCBI NR]
Description(s) found:	gi\|208966364\|dbj\|BAG73196.1\| general transcription factor IIH, polypeptide 3, 34kDa [synthetic construct] [NCBI NR]
Organism:	synthetic construct
Length:	308 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSDEDELNL LVIVVDANPI WWGKQALKES QFTLSKCIDA VMVLGNSHLF MNRSNKLAVI  60
   61 ASHIQESRFL YPGKNGRLGD FFGDPGNPPE FNPSGSKDGK YELLTSANEV IVEEIKDLMT 120
  121 KSDIKGQHTE TLLAGSLAKA LCYIHRMNKE VKDNQEMKSR ILVIKAAEDS ALQYMNFMNV 180
  181 IFAAQKQNIL IDACVLDSDS GLLQQACDIT GGLYLKVPQM PSLLQYLLWV FLPDQDQRSQ 240
  241 LILPPPVHVD YRAACFCHRN LIEIGYVCSV CLSIFCNFSP ICTTCETAFK ISLPPVLKAK 300
  301 KKKLKVSA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..221]	FFAS03	1.99	A domain of Factor B
2	View Details	[222..308]	FFAS03	0.965	Hrs

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
binding	2.68315152218267	bayes_pls_golite062009
nucleic acid binding	2.10023916482665	bayes_pls_golite062009
DNA binding	1.9295508897092	bayes_pls_golite062009
protein complex binding	1.65763332955233	bayes_pls_golite062009
protein binding	1.42792331963866	bayes_pls_golite062009
hydrolase activity	0.589248272940562	bayes_pls_golite062009
structure-specific DNA binding	0.446181458443121	bayes_pls_golite062009
protein dimerization activity	0.244402438311177	bayes_pls_golite062009
protein heterodimerization activity	0.114607758890868	bayes_pls_golite062009
catalytic activity	0.0380261580236634	bayes_pls_golite062009

2

Term	Confidence	Notes
transcription regulator activity	2.84543733401722	bayes_pls_golite062009
binding	2.84147289283175	bayes_pls_golite062009
DNA binding	2.61461572393763	bayes_pls_golite062009
nucleic acid binding	2.59290953932215	bayes_pls_golite062009
endonuclease activity	2.2518780558155	bayes_pls_golite062009
transcription repressor activity	2.05685078783854	bayes_pls_golite062009
transcription factor activity	1.59046392323038	bayes_pls_golite062009
protein binding	1.32925779020231	bayes_pls_golite062009
histone binding	0.920809910112588	bayes_pls_golite062009
chromatin binding	0.887177003087523	bayes_pls_golite062009
transcription activator activity	0.663225694514289	bayes_pls_golite062009
protein deacetylase activity	0.645925926119566	bayes_pls_golite062009
histone deacetylase activity	0.637698619166566	bayes_pls_golite062009
hydrolase activity	0.594292092754636	bayes_pls_golite062009
lysine N-acetyltransferase activity	0.585199046067846	bayes_pls_golite062009
histone acetyltransferase activity	0.585199046067846	bayes_pls_golite062009
sequence-specific DNA binding	0.0471610688739243	bayes_pls_golite062009
transcription factor binding	0.0293954104210474	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle