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Protein Overview: gi|190407080

General Information:
Name(s) found: gi|190407080 [NCBI NR]
Description(s) found:
  • gi|190407080|gb|EDV10347.1| mRNA capping enzyme alpha subunit [Saccharomyces cerevisiae RM11-1a] [NCBI NR]
    • Organism: Saccharomyces cerevisiae RM11-1a
    Length: 459 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLAMESRVA PEIPGLIQPG NVTQDLKMMV CKLLNSPKPT KTFPGSQPVS FQHSDVEEKL  60
   61 LAHDYYVCEK TDGLRVLMFI VINPVTGEQG CFMIDRENNY YLVNGFRFPR LPQKKKEELL 120
  121 ETLQDGTLLD GELVIQTNPM TKLQELRYLM FDCLAINGRC LTQSPTSSRL AHLGKEFFKP 180
  181 YFDLRAAYPN RCTTFPFKIS MKHMDFSYQL VKVAKSLDKL PHLSDGLIFT PVKAPYTAGG 240
  241 KDSLLLKWKP EQENTVDFKL ILDIPMVEDP SLPKDDRNRW YYNYDVKPVF SLYVWQGGAD 300
  301 VNSRLKHFDQ PFDRKEFEIL ERTYRKFAEL SVSDEEWQNL KNLEQPLNGR IVECAKNQET 360
  361 GAWEMLRFRD DKLNGNHTSV VQKVLESIND SVSLEDLEEI VGDIKRCWDE RRANMAGGSG 420
  421 RPLPSQSQNA TLSTSKPVHS QPPSNDKEPK YVDEDDWSD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..47]
    [72..198]    		 PSI-BLAST 149.218487 RNA guanylyltransferase (mRNA capping enzyme); RNA guanylyltransferase (mRNA capping enzyme), N-terminal domain
    2 View Details [48..71]
    [199..253]    		 PSI-BLAST 149.218487 RNA guanylyltransferase (mRNA capping enzyme); RNA guanylyltransferase (mRNA capping enzyme), N-terminal domain
    3 View Details [254..338] PSI-BLAST 149.218487 RNA guanylyltransferase (mRNA capping enzyme); RNA guanylyltransferase (mRNA capping enzyme), N-terminal domain
    4 View Details [339..459] ORFEUS 10.46 RNA guanylyltransferase (mRNA capping enzyme); RNA guanylyltransferase (mRNA capping enzyme), N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • mRNA guanylyltransferase activity
    		•  8.90512192081791 bayes_pls_golite062009
  • RNA guanylyltransferase activity
    		•  8.46124967325993 bayes_pls_golite062009
  • ligase activity, forming phosphoric ester bonds
    		•  2.90848936326491 bayes_pls_golite062009
  • DNA ligase activity
    		•  2.88630907730339 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.49304224824605 bayes_pls_golite062009
  • ligase activity
    		•  2.44151794329612 bayes_pls_golite062009
  • RNA binding
    		•  2.41160981373213 bayes_pls_golite062009
  • DNA binding
    		•  2.3408239279957 bayes_pls_golite062009
  • catalytic activity
    		•  2.15370807854636 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.10110937001387 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.9581702424972 bayes_pls_golite062009
  • binding
    		•  1.82998145778732 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.81524862921454 bayes_pls_golite062009
  • guanylyltransferase activity
    		•  1.64088197294498 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.62996999055328 bayes_pls_golite062009
    		• 1.5765009871268 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.51215866188241 bayes_pls_golite062009
  • protein binding
    		•  1.38006517521813 bayes_pls_golite062009
  • transcription activator activity
    		•  1.24141936405635 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.19236946227657 bayes_pls_golite062009
  • structural molecule activity
    		•  1.16496993393687 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.15212468568198 bayes_pls_golite062009
  • transcription factor activity
    		•  1.14242112812892 bayes_pls_golite062009
  • exoribonuclease activity
    		•  1.10445667068538 bayes_pls_golite062009
  • DNA ligase (ATP) activity
    		•  1.02324195596817 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  0.83268201349295 bayes_pls_golite062009
  • DNA ligase (NAD+) activity
    		•  0.802565778478831 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.583085644017496 bayes_pls_golite062009
  • nuclease activity
    		•  0.57381531077345 bayes_pls_golite062009
  • translation regulator activity
    		•  0.515576958825022 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.510809870824979 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.510809870824979 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.468402630523277 bayes_pls_golite062009
  • mRNA binding
    		•  0.4162128308402 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.2080607201312 bayes_pls_golite062009
  • chromatin binding
    		•  0.19409870825073 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle