| Protein: | lola-PN |
| Organism: | Drosophila melanogaster |
| Length: | 878 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lola-PN.
| Description | E-value | Query Range |
Subject Range |
|
|
619.0 | [0..405] | [875..2426] |
|
Region A: Residues: [1-129] |
1 11 21 31 41 51
| | | | | |
1 MDDDQQFCLR WNNHQSTLIS VFDTLLENET LVDCTLAAEG KFLKAHKVVL SACSPYFATL 60
61 LQEQYDKHPI FILKDVKYQE LRAMMDYMYR GEVNISQDQL AALLKAAESL QIKGLSDNRT 120
121 GGGVAPKPE
|
| Detection Method: |  |
| Confidence: | 32.0 |
| Match: | 1r28A |
| Description: | Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB domain to 2.2 Angstrom |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.03732153795237 | bayes_pls_golite062009 |
| DNA binding | 3.50992893425527 | bayes_pls_golite062009 |
| nucleic acid binding | 3.39650042677839 | bayes_pls_golite062009 |
| transcription repressor activity | 3.34221155527033 | bayes_pls_golite062009 |
| transcription factor activity | 2.77967244868934 | bayes_pls_golite062009 |
| binding | 2.73171412378045 | bayes_pls_golite062009 |
| protein binding | 2.43603601331034 | bayes_pls_golite062009 |
| gated channel activity | 2.31670938272069 | bayes_pls_golite062009 |
| cation channel activity | 2.29487032939987 | bayes_pls_golite062009 |
| ion channel activity | 2.26817638058015 | bayes_pls_golite062009 |
| potassium channel activity | 1.44385468589872 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 1.43775565332764 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.43014386864286 | bayes_pls_golite062009 |
| channel activity | 1.41924822300643 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 1.41924822300643 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 1.41843723045096 | bayes_pls_golite062009 |
| substrate-specific channel activity | 1.4152854884651 | bayes_pls_golite062009 |
| voltage-gated channel activity | 1.40892835925684 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.3794923488776 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 1.37848954483947 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.36107960937272 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.34347609298791 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 1.32720756453806 | bayes_pls_golite062009 |
| transcription activator activity | 1.3134483946218 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 1.2813343017365 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.933012980583336 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 0.69971422997918 | bayes_pls_golite062009 |
| transporter activity | 0.14391700968389 | bayes_pls_golite062009 |
| catalytic activity | 0.112500532859479 | bayes_pls_golite062009 |
| chromatin binding | 0.0908724449159477 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.0733959562343498 | bayes_pls_golite062009 |
|
Region A: Residues: [130-343] |
1 11 21 31 41 51
| | | | | |
1 SSGHHRGGKL SGAYTLEQTK RARLATGGAM DTSGDVSGSR EGSSSPSRRR RKVRRRSMEN 60
61 DAHDNSNSSV LQAAASNQSI LQQTGAGLAV SALVTTQLSS GPAAGTSSQA SSTQQQQPLT 120
121 STNVTKKTES AKLTSSTAAP ASGASASAAV QQAHLHQQQA QTTSDAINTE NVQAQSQGGA 180
181 QGVQGDDEDI DEGSAVGGPN SATGPNPASA SASA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [344-493] |
1 11 21 31 41 51
| | | | | |
1 VHAGVVVKQL ASVVDKSSSN HKHKIKDNSV SSVGSEMVIE PKAEYDDDAH DENVEDLTLD 60
61 EEDMTMEELD QTAGTSQGGE GSSQTYATWQ HDRSQDELGL MAQDAQQRDP QDGYWTILET 120
121 VPYSIASAAP NQTLTTATTL SNGGSSLLTG
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [494-583] |
1 11 21 31 41 51
| | | | | |
1 ATVVVELPPD DLGNPVGNIQ YTIPALTKNA TTNTNTTSLL HKPQATTIQI VKQQHQQQHQ 60
61 QQHQHPQQQH QPQQQQHRQH LTIQQSQTHA
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [584-631] |
1 11 21 31 41 51
| | | | | |
1 RQEYIKIDTS RLEDKMLLRD VMQYGATSIA MAPQSATTTV VSTHPVES
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [632-700] |
1 11 21 31 41 51
| | | | | |
1 GLLLADADEA ERELELEAMK VDQHDEEHLL DDEGYVIEKI HGDGETVNQP QEKLYINGMS 60
61 NIIHTATTM
|
| Detection Method: | |
| Confidence: | 19.69897 |
| Match: | 2gliA |
| Description: | Five-finger GLI1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [701-878] |
1 11 21 31 41 51
| | | | | |
1 TLQPDDCKYA CNVCGKTYKI KGSLKRHKNY ECGVEPNLKC PHCPHKCKCV LAQVVNFVRH 60
61 GPKNQLLCQC GRYYNTLSRL MLHQREECQD FKRFQCDFCL KWFKRRSHLN RHKKLHDAEL 120
121 FLEPLSKQKP KTTSGQNLSH DANTDDEVAT TNPAATEDES NYPFTSEIKI ENEFDEFI
|
| Detection Method: | |
| Confidence: | 57.30103 |
| Match: | 2i13A |
| Description: | No description for 2i13A was found. |
