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View Structure Prediction Details

Protein: FBpp0302532
Organism: Drosophila melanogaster
Length: 562 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0302532.

Description E-value Query
Range		 Subject
Range
FBpp0302531 - type=protein; loc=3R:complement(14079276..14080038,14080097..14080913,14081039..14081102); ID=FBpp03...
 390.0 [0..1] [562..1]

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Predicted Domain #1
Region A:
Residues: [1-89] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFMNPVDMV DEDAADLQFP KVALLHIFTT LNCLFAVEPL GPQVKRFIHA HQNEHTRNSM  60
   61 VLYNPHTLHR YLEEMEEKTR DQNSSVPSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.30103
Match: 1eg3A
Description: Dystrophin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [90-148] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKDANRCATC RCSLTEPYIK CSECLDTLLC LQCFSRGKEA FSHRNNHAYI IVRDNIQVF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.30103
Match: 2e5rA
Description: No description for 2e5rA was found.

Predicted Domain #3
Region A:
Residues: [149-324] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADEPHWTARD ERILLKTLRT HGYGNWEAVS QALDQRHEPA EVRRHYHDCY FGGIFERLLN  60
   61 LKHARDSYVP ERMPYVFKMR SLDPPRHDDI ASMQFRLSAG YRCARGDFDT PYDTSAESLL 120
  121 SIMVDHRGRD DDNEASESEF EREVTEELQL GLVRAYNNRL RERQRRYKIM RQHGLI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.84
Match: 1a5jA
Description: CHICKEN B-MYB DNA BINDING DOMAIN, REPEAT 2 AND REPEAT3, NMR, 32 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
lysine N-acetyltransferase activity 5.78270240334849 bayes_pls_golite062009
histone acetyltransferase activity 5.78270240334849 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 5.44968936347013 bayes_pls_golite062009
transcription regulator activity 4.86538715425734 bayes_pls_golite062009
N-acyltransferase activity 4.53404381270892 bayes_pls_golite062009
DNA binding 4.40186699787632 bayes_pls_golite062009
N-acetyltransferase activity 4.38345537045529 bayes_pls_golite062009
nucleic acid binding 4.28652307290136 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.10362956884303 bayes_pls_golite062009
RNA polymerase activity 3.99233443365099 bayes_pls_golite062009
DNA-directed RNA polymerase activity 3.99233443365099 bayes_pls_golite062009
acetyltransferase activity 3.81897719505269 bayes_pls_golite062009
transcription factor activity 3.78935192723648 bayes_pls_golite062009
acyltransferase activity 3.35931919126926 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.31384699789032 bayes_pls_golite062009
transferase activity 3.16343875008119 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.09869056563841 bayes_pls_golite062009
binding 2.92574888336072 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.91588376840709 bayes_pls_golite062009
nucleotidyltransferase activity 2.87182202022318 bayes_pls_golite062009
sequence-specific DNA binding 2.15328641013602 bayes_pls_golite062009
transcription repressor activity 1.69615348178304 bayes_pls_golite062009
transcription activator activity 1.5973137667873 bayes_pls_golite062009
chromatin binding 1.46954724788757 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.44773725829085 bayes_pls_golite062009
transcription factor binding 1.24678737091956 bayes_pls_golite062009
protein deacetylase activity 1.23476914879396 bayes_pls_golite062009
histone deacetylase activity 1.18710646783152 bayes_pls_golite062009
protein binding 0.795494287543952 bayes_pls_golite062009
transcription cofactor activity 0.691780246385357 bayes_pls_golite062009
DNA-dependent ATPase activity 0.658518317984762 bayes_pls_golite062009
deacetylase activity 0.534082291544628 bayes_pls_golite062009
histone binding 0.489784140732052 bayes_pls_golite062009
cytoskeletal protein binding 0.244471307852075 bayes_pls_golite062009
telomeric DNA binding 0.233668696331578 bayes_pls_golite062009
transcription coactivator activity 0.201150053959035 bayes_pls_golite062009
DNA helicase activity 0.192832786095412 bayes_pls_golite062009
structure-specific DNA binding 0.0880065228906077 bayes_pls_golite062009
transcription corepressor activity 0.0723215858239072 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [325-442] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNRTVSWIS KYVHAFGSDA SCMRFLGFMQ ICPDPIKFDM LLESLRYYRE LHSQLHKLYD  60
   61 LREHGVRTLS GAKLYARLSK ERQQAQRDYS RLKQTDAFDW QQLVQHYESN RSGDPGPL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [443-562] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AINSKLYVMN TRRKASPIEI GGGKHFTHCL TPTEYNFSLI PDLPGYSKLD DGERKLCSVA  60
   61 RLVPQSYLDY KNQLVTEQAK LGYLRLADAR RLIKIDVNKT RQIYDFLLEH GHISRPPSYG 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.0
Match: 2cujA
Description: Solution structure of SWIRM domain of mouse transcriptional adaptor 2-like
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
lysine N-acetyltransferase activity 5.80609397811031 bayes_pls_golite062009
histone acetyltransferase activity 5.80609397811031 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 5.49431089902672 bayes_pls_golite062009
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
N-acyltransferase activity 4.57418118498868 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
N-acetyltransferase activity 4.37954729923498 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.09369451338399 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
RNA polymerase activity 3.9883025551666 bayes_pls_golite062009
DNA-directed RNA polymerase activity 3.9883025551666 bayes_pls_golite062009
acetyltransferase activity 3.80908511328212 bayes_pls_golite062009
acyltransferase activity 3.35206890637362 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.30532537006075 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.16896789933192 bayes_pls_golite062009
transferase activity 3.10582783156108 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.08442186629685 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
nucleotidyltransferase activity 2.86344939956632 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.73068440195944 bayes_pls_golite062009
chromatin binding 1.68956710349366 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
protein deacetylase activity 1.23680480131205 bayes_pls_golite062009
histone deacetylase activity 1.18932416576802 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
DNA-dependent ATPase activity 0.666799964992178 bayes_pls_golite062009
histone binding 0.557787598121402 bayes_pls_golite062009
deacetylase activity 0.530687254192222 bayes_pls_golite062009
telomeric DNA binding 0.284650049512347 bayes_pls_golite062009
transcription coactivator activity 0.2679415219517 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009
cytoskeletal protein binding 0.236060274498333 bayes_pls_golite062009
DNA helicase activity 0.187022204923867 bayes_pls_golite062009
structure-specific DNA binding 0.105174598157041 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle