YRC Public Data Repository - Protein Structure Prediction

Protein:	YGIS_ECOLI
Organism:	Escherichia coli
Length:	535 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGIS_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|148876390, gi... - gi\|153828148\|ref\|ZP_01980815.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prote... tr\|A2PTK6\|A2PTK6... - Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OS=Vibrio cholerae MZO-3 GN=o... gi\|254225487, gi... - gi\|75820574\|ref\|ZP_00750618.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|153802139, gi... - gi\|153802139\|ref\|ZP_01956725.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prote...	501.0	[0..1]	[535..1]
gi\|75830269, gi\|... - gi\|75830269\|ref\|ZP_00759550.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|121587071, gi... - gi\|121587071\|ref\|ZP_01676848.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prote... gi\|146315274, gi... - gi\|75826392\|ref\|ZP_00755827.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|153816918, gi... - gi\|153816918\|ref\|ZP_01969585.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prote... gi\|75817294, gi\|... - gi\|75817294\|ref\|ZP_00747746.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|153821878, gi... - gi\|229511017\|ref\|ZP_04400496.1\| oligopeptide ABC transporter periplasmic oligopeptide-binding protei... gi\|227009152, gi... - gi\|227081264\|ref\|YP_002809815.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prot... gi\|229357536, gi... - gi\|229505313\|ref\|ZP_04394823.1\| oligopeptide ABC transporter periplasmic oligopeptide-binding protei... gi\|229344853, gi... - gi\|229518138\|ref\|ZP_04407582.1\| oligopeptide ABC transporter periplasmic oligopeptide-binding protei... gi\|229370987, gi... - gi\|229608332\|ref\|YP_002878980.1\| oligopeptide ABC transporter periplasmic oligopeptide-binding prote... gi\|9655560, gi\|1... - gi\|9655560\|gb\|AAF94250.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding protein [Vi... gi\|11277225 - pir\|\|B82242 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein VC1091 [imported]... gi\|254291515, gi... - gi\|254291515\|ref\|ZP_04962306.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prote...	501.0	[0..1]	[535..1]
tr\|D7H7T9\|D7H7T9... - Oligopeptide ABC transporter OS=Vibrio cholerae RC385 GN=VCRC385_00739 PE=4 SV=1 gi\|254223471, gi... - gi\|75824305\|ref\|ZP_00753763.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen...	497.0	[0..1]	[535..1]
gi\|77972677 - gi\|77972677\|ref\|ZP_00828237.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen...	491.0	[0..2]	[535..5]
gi\|77996922, gi\|... - gi\|78044807\|ref\|YP_359974.1\| oligopeptide/dipeptide ABC transporter, peptide-binding protein [Carbox...	486.0	[0..1]	[528..1]
gi\|77960746 - gi\|77960746\|ref\|ZP_00824604.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen...	486.0	[0..2]	[535..5]
gi\|77957078, gi\|... - gi\|77957078\|ref\|ZP_00821144.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen...	486.0	[0..2]	[535..5]
gi\|91212439, gi\|... - gi\|91212439\|ref\|YP_542425.1\| putative binding protein [Escherichia coli UTI89], gi\|91074013\|gb\|ABE08... gi\|237706228, gi... - gi\|237706228\|ref\|ZP_04536709.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22689...	484.0	[0..1]	[535..22]
gi\|47808, gi\|724... - pir\|\|QREBOA oligopeptide-binding protein precursor - Salmonella typhimurium, gi\|47808\|emb\|CAA27785.1... gi\|47802\|emb\|CAA... - unnamed protein product [Salmonella typhimurium], unnamed protein product [Salmonella typhimurium]	483.0	[0..2]	[535..7]
gi\|37198130, gi\|... - gi\|37679387\|ref\|NP_933996.1\| ABC-type oligopeptide transport system, periplasmic component [Vibrio v...	483.0	[0..15]	[534..39]

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Predicted Domain #1

Region A:
Residues: [1-535]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYTRNLLWLV SLVSAAPLYA ADVPANTPLA PQQVFRYNNH SDPGTLDPQK VEENTAAQIV  60
   61 LDLFEGLVWM DGEGQVQPAQ AERWEILDGG KRYIFHLRSG LQWSDGQPLT AEDFVLGWQR 120
  121 AVDPKTASPF AGYLAQAHIN NAAAIVAGKA DVTSLGVKAT DDRTLEVTLE QPVPWFTTML 180
  181 AWPTLFPVPH HVIAKHGDSW SKPENMVYNG AFVLDQWVVN EKITARKNPK YRDAQHTVLQ 240
  241 QVEYLALDNS VTGYNRYRAG EVDLTWVPAQ QIPAIEKSLP GELRIIPRLN SEYYNFNLEK 300
  301 PPFNDVRVRR ALYLTVDRQL IAQKVLGLRT PATTLTPPEV KGFSATTFDE LQKPMSERVA 360
  361 MAKALLKQAG YDASHPLRFE LFYNKYDLHE KTAIALSSEW KKWLGAQVTL RTMEWKTYLD 420
  421 ARRAGDFMLS RQSWDATYND ASSFLNTLKS DSEENVGHWK NAQYDALLNQ ATQITDATKR 480
  481 NALYQQAEVI INQQAPLIPI YYQPLIKLLK PYVGGFPLHN PQDYVYSKEL YIKAH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	134.0
Match:	1b05A
Description:	Oligo-peptide binding protein (OPPA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ATPase activity, coupled to transmembrane movement of substances	7.32513858490159	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	7.32461921873446	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	7.32461921873446	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	7.30967709770689	bayes_pls_golite062009
primary active transmembrane transporter activity	7.29915074349679	bayes_pls_golite062009
oligopeptide transporter activity	7.2433462247746	bayes_pls_golite062009
active transmembrane transporter activity	7.22701734359888	bayes_pls_golite062009
peptide transporter activity	6.65358482101265	bayes_pls_golite062009
ATPase activity, coupled	6.6184830833742	bayes_pls_golite062009
ATPase activity	6.25872881857398	bayes_pls_golite062009
dipeptide transporter activity	6.15818525311031	bayes_pls_golite062009
nucleoside-triphosphatase activity	5.90322606085411	bayes_pls_golite062009
pyrophosphatase activity	5.82359353784758	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	5.80191380928519	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	5.80159621701122	bayes_pls_golite062009
peptide-transporting ATPase activity	4.88181218330665	bayes_pls_golite062009
oligopeptide-transporting ATPase activity	4.33503585684315	bayes_pls_golite062009
hydrolase activity	4.03317966718526	bayes_pls_golite062009
transporter activity	3.92658561501282	bayes_pls_golite062009
transmembrane transporter activity	3.71430307970333	bayes_pls_golite062009
substrate-specific transporter activity	3.34421502810243	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	3.25040168593981	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	3.16446457499691	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.76254706952599	bayes_pls_golite062009
molybdate transmembrane-transporting ATPase activity	2.58578176144479	bayes_pls_golite062009
molybdate ion transmembrane transporter activity	2.58578176144479	bayes_pls_golite062009
ion transmembrane transporter activity	1.84929214408108	bayes_pls_golite062009
binding	1.54172013140566	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	0.88623763826001	bayes_pls_golite062009
anion transmembrane transporter activity	0.75669016367838	bayes_pls_golite062009
polyamine transmembrane transporter activity	0.74959887541426	bayes_pls_golite062009
iron ion transmembrane transporter activity	0.3752347482824	bayes_pls_golite062009
amine transmembrane transporter activity	0.372828805396439	bayes_pls_golite062009
cation transmembrane transporter activity	0.343508026849565	bayes_pls_golite062009
amine-transporting ATPase activity	0.22884273975653	bayes_pls_golite062009
sulfate transmembrane-transporting ATPase activity	0.0940079640524907	bayes_pls_golite062009
polyamine-transporting ATPase activity	0.0497853931936705	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.0237973852493387	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: