YRC Public Data Repository - Protein Structure Prediction

Protein:	SAPA_ECOLI
Organism:	Escherichia coli
Length:	547 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAPA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|15602101, gi\|... - gi\|15602101\|ref\|NP_245173.1\| hypothetical protein PM0236 [Pasteurella multocida subsp. multocida str...	544.0	[0..1]	[540..1]
gi\|218372296, gi... - gi\|218702310\|ref\|YP_002409939.1\| dipeptide transporter ; periplasmic-binding component of ABC superf... gi\|117625828, gi... - gi\|117625828\|ref\|YP_859151.1\| dipeptide transporter protein DppA [Escherichia coli APEC O1], gi\|1155... gi\|218367391, gi... - gi\|218560622\|ref\|YP_002393535.1\| dipeptide transporter ; periplasmic-binding component of ABC superf... gi\|218429393, gi... - gi\|218691829\|ref\|YP_002400041.1\| dipeptide transporter ; periplasmic-binding component of ABC superf... gi\|170679624, gi... - gi\|170679624\|ref\|YP_001745830.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [E... gi\|191170334, gi... - gi\|191170334\|ref\|ZP_03031887.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Es... gi\|237703312, gi... - gi\|237703312\|ref\|ZP_04533793.1\| periplasmic dipeptide transporter [Escherichia sp. 3_2_53FAA], gi\|22... gi\|26250183, gi\|... - gi\|26250183\|ref\|NP_756223.1\| periplasmic dipeptide transport protein precursor [Escherichia coli CFT... gi\|110643793, gi... - gi\|110643793\|ref\|YP_671523.1\| periplasmic dipeptide transport protein precursor [Escherichia coli 53... gi\|91213056, gi\|... - gi\|91213056\|ref\|YP_543042.1\| periplasmic dipeptide transport protein precursor [Escherichia coli UTI... gi\|227839288, gi... - gi\|227883708\|ref\|ZP_04001513.1\| dipeptide/oligopeptide/nickel (Ni2+) ABC superfamily ATP binding cas...	543.0	[0..1]	[539..1]
gi\|218556099, gi... - gi\|218556099\|ref\|YP_002389012.1\| dipeptide transporter ; periplasmic-binding component of ABC superf... DPPA_ECOLI - Periplasmic dipeptide transport protein precursor (Dipeptide-binding protein) (DBP) - Escherichia co... gi\|209914267, gi... - gi\|209921008\|ref\|YP_002295092.1\| dipeptide ABC transporter substrate binding component [Escherichia ... gi\|194435630, gi... - gi\|194435630\|ref\|ZP_03067733.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Es... gi\|194428690, gi... - gi\|194428690\|ref\|ZP_03061227.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Es... gi\|218697257, gi... - gi\|218697257\|ref\|YP_002404924.1\| dipeptide transporter ; periplasmic-binding component of ABC superf... gi\|169753154, gi... - gi\|170018226\|ref\|YP_001723180.1\| 4-phytase [Escherichia coli ATCC 8739], gi\|169753154\|gb\|ACA75853.1\|... EG10248 - dipeptide /heme ABC transporter periplasmic binding protein; dipeptide chemotaxis receptor / Dipeptid... gi\|192932707, gi... - gi\|193061917\|ref\|ZP_03043014.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Es... gi\|238902633, gi... - gi\|238902633\|ref\|YP_002928429.1\| dipeptide transporter [Escherichia coli BW2952], gi\|238860779\|gb\|AC... gi\|157163019, gi... - gi\|157163019\|ref\|YP_001460337.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [E... gi\|191165311, gi... - gi\|191165311\|ref\|ZP_03027154.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Es... gi\|157159059, gi... - gi\|157159059\|ref\|YP_001465018.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [E... gi\|188494631, gi... - gi\|188494631\|ref\|ZP_03001901.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Es... gi\|254290218, gi... - gi\|254290218\|ref\|YP_003055966.1\| dipeptide transporter [Escherichia coli BL21(DE3)], gi\|253979525\|gb... gi\|170083053, gi... - gi\|170083053\|ref\|YP_001732373.1\| peptide ABC transporter periplasmic substrate-binding protein [Esch... gi\|251786789, gi... - gi\|251786789\|ref\|YP_003001093.1\| hypothetical protein B21_03346 [Escherichia coli BL21], gi\|24237906... gi\|253975369, gi... - gi\|254163468\|ref\|YP_003046576.1\| dipeptide transporter [Escherichia coli B str. REL606], gi\|25397536... gi\|226839232, gi... - gi\|254038726\|ref\|ZP_04872782.1\| dipeptide ABC transporter [Escherichia sp. 1_1_43], gi\|226839232\|gb\|... gi\|89110469, gi\|... - gi\|89110469\|ref\|AP_004249.1\| dipeptide transporter [Escherichia coli str. K-12 substr. W3110], gi\|85... EG10248 - dipeptide /heme ABC transporter periplasmic binding protein; dipeptide chemotaxis receptor / Dipeptid... gi\|124499882, gi... - gi\|124529424\|ref\|ZP_01700428.1\| extracellular solute-binding protein, family 5 [Escherichia coli B],...	541.0	[0..1]	[539..1]
gi\|82779575, gi\|... - gi\|82779575\|ref\|YP_405924.1\| dipeptide transport protein [Shigella dysenteriae Sd197], gi\|81243723\|g... gi\|168765953, gi... - gi\|189364705\|gb\|EDU83124.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Escher... gi\|189369929, gi... - gi\|189369929\|gb\|EDU88345.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Escher... gi\|168753358, gi... - gi\|189359183\|gb\|EDU77602.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Escher... gi\|188018308, gi... - gi\|188018308\|gb\|EDU56430.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Escher... gi\|30065176, gi\|... - gi\|30065176\|ref\|NP_839347.1\| dipeptide transport protein [Shigella flexneri 2a str. 2457T], gi\|30043... gi\|13363898, gi\|... - gi\|15833678\|ref\|NP_312451.1\| dipeptide transport protein [Escherichia coli O157:H7], gi\|13363898\|dbj... gi\|209755314, gi... - pir\|\|H91181 dipeptide transport protein ECs4424 [imported] - Escherichia coli (strain O157:H7, subst... gi\|24114813, gi\|... - gi\|24114813\|ref\|NP_709323.1\| dipeptide transport protein [Shigella flexneri 2a str. 301], gi\|2405404... gi\|13363898, gi\|... - gi\|15833678\|ref\|NP_312451.1\| dipeptide transport protein [Escherichia coli O157:H7 str. Sakai], gi\|1... gi\|110807363, gi... - gi\|110807363\|ref\|YP_690883.1\| dipeptide transport protein [Shigella flexneri 5 str. 8401], gi\|110616... gi\|217320543, gi... - gi\|217324322\|ref\|ZP_03440406.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Es... gi\|209396782, gi... - gi\|209396782\|ref\|YP_002273027.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [E... gi\|254795498, gi... - gi\|254795498\|ref\|YP_003080335.1\| dipeptide transporter, periplasmic-binding component of ABC superfa... gi\|189380041, gi... - gi\|189380041\|gb\|EDU98457.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Escher... gi\|189374498, gi... - gi\|189374498\|gb\|EDU92914.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Escher... gi\|189002410, gi... - gi\|189002410\|gb\|EDU71396.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Escher... gi\|168772500, gi... - gi\|187771446\|gb\|EDU35290.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Escher... gi\|208741610, gi... - gi\|208821487\|ref\|ZP_03261807.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Es... gi\|208812644, gi... - gi\|208812644\|ref\|ZP_03253973.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Es... gi\|208805733, gi... - gi\|208805733\|ref\|ZP_03248070.1\| dipeptide ABC transporter, periplasmic dipeptide-binding protein [Es... gi\|195935072 - gi\|195935072\|ref\|ZP_03080454.1\| dipeptide transport protein [Escherichia coli O157:H7 str. EC4024]	541.0	[0..1]	[539..1]
gi\|25296387 - pir\|\|D86028 dipeptide transport protein [imported] - Escherichia coli (strain O157:H7, substrain ED... gi\|12518268, gi\|... - gi\|15804087\|ref\|NP_290125.1\| dipeptide transport protein [Escherichia coli O157:H7 EDL933], gi\|12518...	541.0	[0..1]	[539..1]
gi\|73857680, gi\|... - gi\|74314203\|ref\|YP_312622.1\| dipeptide transport protein [Shigella sonnei Ss046], gi\|73857680\|gb\|AAZ...	540.0	[0..1]	[539..1]
gi\|16762672 - gi\|16762672\|ref\|NP_458289.1\| periplasmic dipeptide transport protein precursor [Salmonella enterica ... gi\|16504978, gi\|... - gi\|25296405\|pir\|\|AE0983 periplasmic dipeptide transport protein precursor STY4168 [imported] - Salmo... gi\|29139796, gi\|... - gi\|29144159\|ref\|NP_807501.1\| periplasmic dipeptide transport protein precursor [Salmonella enterica ...	540.0	[0..4]	[539..6]
gi\|56415532, gi\|... - gi\|56415532\|ref\|YP_152607.1\| periplasmic dipeptide transport protein precursor [Salmonella enterica ...	539.0	[0..4]	[539..6]
gi\|75242664 - gi\|75242664\|ref\|ZP_00726408.1\| COG0747: ABC-type dipeptide transport system, periplasmic component [...	538.0	[0..18]	[539..4]
gi\|16766917, gi\|... - gi\|16766917\|ref\|NP_462532.1\| dipeptide transport protein [Salmonella typhimurium LT2], gi\|16422195\|g... lcl\|NC_016856.1_... - [gene=dppA] [protein=dipeptide transport protein] [protein_id=YP_005239858.1] [location=complement(3...	538.0	[0..4]	[539..6]

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Predicted Domain #1

Region A:
Residues: [1-547]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRQVLSSLLV IAGLVSGQAI AAPESPPHAD IRDSGFVYCV SGQVNTFNPS KASSGLIVDT  60
   61 LAAQFYDRLL DVDPYTYRLM PELAESWEVL DNGATYRFHL RRDVPFQKTD WFTPTRKMNA 120
  121 DDVVFTFQRI FDRNNPWHNV NGSNFPYFDS LQFADNVKSV RKLDNHTVEF RLAQPDASFL 180
  181 WHLATHYASV MSAEYARKLE KEDRQEQLDR QPVGTGPYQL SEYRAGQFIR LQRHDDFWRG 240
  241 KPLMPQVVVD LGSGGTGRLS KLLTGECDVL AWPAASQLSI LRDDPRLRLT LRPGMNVAYL 300
  301 AFNTAKPPLN NPAVRHALAL AINNQRLMQS IYYGTAETAA SILPRASWAY DNEAKITEYN 360
  361 PAKSREQLKS LGLENLTLKL WVPTRSQAWN PSPLKTAELI QADMAQVGVK VVIVPVEGRF 420
  421 QEARLMDMSH DLTLSGWATD SNDPDSFFRP LLSCAAIHSQ TNLAHWCDPK FDSVLRKALS 480
  481 SQQLAARIEA YDEAQSILAQ ELPILPLASS LRLQAYRYDI KGLVLSPFGN ASFAGVYREK 540
  541 QDEVKKP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	151.0
Match:	1dppA
Description:	Dipeptide-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ATPase activity, coupled to transmembrane movement of substances	7.32513858490159	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	7.32461921873446	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	7.32461921873446	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	7.30967709770689	bayes_pls_golite062009
primary active transmembrane transporter activity	7.29915074349679	bayes_pls_golite062009
oligopeptide transporter activity	7.2433462247746	bayes_pls_golite062009
active transmembrane transporter activity	7.22701734359888	bayes_pls_golite062009
peptide transporter activity	6.65358482101265	bayes_pls_golite062009
ATPase activity, coupled	6.6184830833742	bayes_pls_golite062009
ATPase activity	6.25872881857398	bayes_pls_golite062009
dipeptide transporter activity	6.15818525311031	bayes_pls_golite062009
nucleoside-triphosphatase activity	5.90322606085411	bayes_pls_golite062009
pyrophosphatase activity	5.82359353784758	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	5.80191380928519	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	5.80159621701122	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	4.88991949355775	bayes_pls_golite062009
peptide-transporting ATPase activity	4.88181218330665	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	4.78886400771857	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.68307627076676	bayes_pls_golite062009
oligopeptide-transporting ATPase activity	4.33503585684315	bayes_pls_golite062009
ion transmembrane transporter activity	4.22641590829276	bayes_pls_golite062009
molybdate transmembrane-transporting ATPase activity	4.17228995326213	bayes_pls_golite062009
molybdate ion transmembrane transporter activity	4.17228995326213	bayes_pls_golite062009
hydrolase activity	4.03317966718526	bayes_pls_golite062009
transporter activity	3.92658561501282	bayes_pls_golite062009
iron ion transmembrane transporter activity	3.72178802654265	bayes_pls_golite062009
transmembrane transporter activity	3.71430307970333	bayes_pls_golite062009
substrate-specific transporter activity	3.34421502810243	bayes_pls_golite062009
cation transmembrane transporter activity	2.86948925100516	bayes_pls_golite062009
metal ion transmembrane transporter activity	2.8310008752622	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	2.70046464278671	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	2.62312131886704	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.24148099938567	bayes_pls_golite062009
anion transmembrane transporter activity	2.18878964063845	bayes_pls_golite062009
nickel ion binding	1.93170720780895	bayes_pls_golite062009
sulfate transmembrane-transporting ATPase activity	1.65531524773788	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	1.64195930233359	bayes_pls_golite062009
binding	1.54172013140566	bayes_pls_golite062009
molybdate ion binding	1.13562285564085	bayes_pls_golite062009
polyamine transmembrane transporter activity	0.74959887541426	bayes_pls_golite062009
sulfate transmembrane transporter activity	0.41724711755287	bayes_pls_golite062009
amine transmembrane transporter activity	0.372828805396439	bayes_pls_golite062009
amine-transporting ATPase activity	0.22884273975653	bayes_pls_golite062009
phosphate transmembrane-transporting ATPase activity	0.0631122887331796	bayes_pls_golite062009
polyamine-transporting ATPase activity	0.0497853931936705	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: