| Protein: | MCM6 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1017 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCM6.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1017] | [1..1017] |
|
|
0.0 | [4..1014] | [9..1002] |
|
|
0.0 | [6..1009] | [78..1031] |
|
|
0.0 | [17..1010] | [1..972] |
|
|
0.0 | [16..1014] | [4..880] |
|
|
0.0 | [1..1008] | [1..971] |
|
|
0.0 | [159..1009] | [1..823] |
|
|
0.0 | [172..1009] | [13..821] |
|
|
0.0 | [28..1010] | [2..915] |
|
Region A: Residues: [1-162] |
1 11 21 31 41 51
| | | | | |
1 MSSPFPADTP SSNRPSNSSP PPSSIGAGFG SSSGLDSQIG SRLHFPSSSQ PHVSNSQTGP 60
61 FVNDSTQFSS QRLQTDGSAT NDMEGNEPAR SFKSRALNHV KKVDDVTGEK VREAFEQFLE 120
121 DFSVQSTDTG EVEKVYRAQI EFMKIYDLNT IYIDYQHLSM RE
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [163-792] |
1 11 21 31 41 51
| | | | | |
1 NGALAMAISE QYYRFLPFLQ KGLRRVVRKY APELLNTSDS LKRSEGDEGQ ADEDEQQDDD 60
61 MNGSSLPRDS GSSAAPGNGT SAMATRSITT STSPEQTERV FQISFFNLPT VHRIRDIRSE 120
121 KIGSLLSISG TVTRTSEVRP ELYKASFTCD MCRAIVDNVE QSFKYTEPTF CPNPSCENRA 180
181 FWTLNVTRSR FLDWQKVRIQ ENANEIPTGS MPRTLDVILR GDSVERAKPG DRCKFTGVEI 240
241 VVPDVTQLGL PGVKPSSTLD TRGISKTTEG LNSGVTGLRS LGVRDLTYKI SFLACHVISI 300
301 GSNIGASSPD ANSNNRETEL QMAANLQANN VYQDNERDQE VFLNSLSSDE INELKEMVKD 360
361 EHIYDKLVRS IAPAVFGHEA VKKGILLQML GGVHKSTVEG IKLRGDINIC VVGDPSTSKS 420
421 QFLKYVVGFA PRSVYTSGKA SSAAGLTAAV VRDEEGGDYT IEAGALMLAD NGICCIDEFD 480
481 KMDISDQVAI HEAMEQQTIS IAKAGIHATL NARTSILAAA NPVGGRYNRK LSLRGNLNMT 540
541 APIMSRFDLF FVILDDCNEK IDTELASHIV DLHMKRDEAI EPPFSAEQLR RYIKYARTFK 600
601 PILTKEARSY LVEKYKELRK DDAQGFSRSS
|
| Detection Method: | |
| Confidence: | 39.09691 |
| Match: | 1qvrA_ |
| Description: | Crystal Structure Analysis of ClpB |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA clamp loader activity | 4.91429252297969 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 4.80695929076807 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 2.72462789867829 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.66107861968804 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| DNA helicase activity | 2.2817164193758 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.13284212711072 | bayes_pls_golite062009 |
| DNA binding | 2.12258000781149 | bayes_pls_golite062009 |
| transcription regulator activity | 2.09345198747025 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 1.88455339138556 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.62491387774159 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.53142082854758 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.52938239070386 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.52887308780164 | bayes_pls_golite062009 |
| nucleotide binding | 1.52746968836881 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.47858140861683 | bayes_pls_golite062009 |
| microtubule motor activity | 1.35938517416356 | bayes_pls_golite062009 |
| ATP binding | 1.23942044024113 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.21044170258803 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.20315703345493 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.19481945569892 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| kinase activity | 1.11120928120082 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.05408274676326 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.971476020912368 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.928091843881235 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.908046791062776 | bayes_pls_golite062009 |
| transcription factor activity | 0.887108427603557 | bayes_pls_golite062009 |
| structural molecule activity | 0.86514677273731 | bayes_pls_golite062009 |
| hydrogen ion transporting ATP synthase activity, rotational mechanism | 0.8469248456592 | bayes_pls_golite062009 |
| motor activity | 0.61636596887462 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.421921195209539 | bayes_pls_golite062009 |
| single-stranded DNA binding | 0.406600732518248 | bayes_pls_golite062009 |
| protein kinase activity | 0.351308564667977 | bayes_pls_golite062009 |
| translation regulator activity | 0.29096092258568 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.274994961137851 | bayes_pls_golite062009 |
| RNA helicase activity | 0.18426050934025 | bayes_pls_golite062009 |
| transferase activity | 0.175269600441384 | bayes_pls_golite062009 |
| protein binding | 0.170837278876362 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.156278588350022 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.147579541298736 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 0.14606996093053 | bayes_pls_golite062009 |
| mismatched DNA binding | 0.13366911641814 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 0.13050483816765 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.113504049290503 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.111293884322157 | bayes_pls_golite062009 |
| 3'-5' DNA helicase activity | 0.0769112340058804 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.0272673919333979 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 0.0223627159838333 | bayes_pls_golite062009 |
|
Region A: Residues: [793-931] |
1 11 21 31 41 51
| | | | | |
1 YRITVRQLES MIRLSEAIAR ANCVDEITPS FIAEAYDLLR QSIIRVDVDD VEMDEEFDNI 60
61 ESQSHAASGN NDDNDDGTGS GVITSEPPAD IEEGQSEATA RPGTSEKKKT TVTYDKYVSM 120
121 MNMIVRKIAE VDREGAEEL
|
| Detection Method: | |
| Confidence: | 19.221849 |
| Match: | 1um8A_ |
| Description: | Crystal structure of helicobacter pylori ClpX |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [932-1017] |
1 11 21 31 41 51
| | | | | |
1 TAVDIVDWYL LQKENDLGSL AEYWEERRLA FKVIKRLVKD RILMEIHGTR HNLRDLENEE 60
61 NENNKTVYVI HPNCEVLDQL EPQDSS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
