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View Structure Prediction Details

Protein: CDPK6_ARATH
Organism: Arabidopsis thaliana
Length: 544 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDPK6_ARATH.

Description E-value Query
Range
Subject
Range
gi|20453015 - gi|20453015|gb|AAL68972.1| calmodulin-like-domain protein kinase CPK2 [Cucurbita maxima]
438.0 [0..1] [543..1]

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Predicted Domain #1
Region A:
Residues: [1-348]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNSCRGSFK DKIYEGNHSR PEENSKSTTT TVSSVHSPTT DQDFSKQNTN PALVIPVKEP  60
   61 IMRRNVDNQS YYVLGHKTPN IRDLYTLSRK LGQGQFGTTY LCTDIATGVD YACKSISKRK 120
  121 LISKEDVEDV RREIQIMHHL AGHKNIVTIK GAYEDPLYVH IVMELCAGGE LFDRIIHRGH 180
  181 YSERKAAELT KIIVGVVEAC HSLGVMHRDL KPENFLLVNK DDDFSLKAID FGLSVFFKPG 240
  241 QIFKDVVGSP YYVAPEVLLK HYGPEADVWT AGVILYILLS GVPPFWAETQ QGIFDAVLKG 300
  301 YIDFDTDPWP VISDSAKDLI RKMLCSSPSE RLTAHEVLRH PWICENGV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.221849
Match: 1opkA
Description: Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphotransferase activity, alcohol group as acceptor 5.49988294224815 bayes_pls_golite062009
protein kinase activity 5.4586557943719 bayes_pls_golite062009
kinase activity 5.3287080791198 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.96052051118534 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
calmodulin-dependent protein kinase activity 4.31938467136214 bayes_pls_golite062009
transferase activity 3.97138602499442 bayes_pls_golite062009
binding 2.74863538127007 bayes_pls_golite062009
tubulin binding 2.18641675163967 bayes_pls_golite062009
cytoskeletal protein binding 2.12615078788254 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
microtubule binding 1.88110801192607 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
insulin receptor substrate binding 1.62657794525303 bayes_pls_golite062009
protein tyrosine kinase activity 1.3898059094397 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.38496328649031 bayes_pls_golite062009
molecular adaptor activity 1.33740973673697 bayes_pls_golite062009
actin binding 1.33479685165255 bayes_pls_golite062009
gamma-tubulin binding 1.28511591054866 bayes_pls_golite062009
receptor signaling protein activity 1.27291233344322 bayes_pls_golite062009
SH3/SH2 adaptor activity 1.2323381312171 bayes_pls_golite062009
protein binding 1.22565748038754 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
protein binding, bridging 0.83823250804321 bayes_pls_golite062009
MAP kinase activity 0.81943579965027 bayes_pls_golite062009
structural constituent of cytoskeleton 0.612883428421652 bayes_pls_golite062009
transporter activity 0.553953601841147 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.499492353295369 bayes_pls_golite062009
protein serine/threonine/tyrosine kinase activity 0.48345772948903 bayes_pls_golite062009
protein phosphorylated amino acid binding 0.43808715710519 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
transmembrane transporter activity 0.37676337669549 bayes_pls_golite062009
MAP kinase kinase kinase activity 0.37115026509016 bayes_pls_golite062009
MAP kinase kinase activity 0.35402045013148 bayes_pls_golite062009
protein complex binding 0.343240719858581 bayes_pls_golite062009
phosphoinositide 3-kinase regulator activity 0.272902474317891 bayes_pls_golite062009
signal transducer activity 0.270054246024761 bayes_pls_golite062009
molecular transducer activity 0.270054246024761 bayes_pls_golite062009
actin filament binding 0.2403700250846 bayes_pls_golite062009
substrate-specific transporter activity 0.0611721261859464 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.0556163711947139 bayes_pls_golite062009
transmembrane receptor activity 0.00652065412910241 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [349-401]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APDRALDPAV LSRLKQFSAM NKLKKMALKV IAESLSEEEI AGLRAMFEAM DTD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.69897
Match: 2jc6A
Description: No description for 2jc6A was found.

Predicted Domain #3
Region A:
Residues: [402-544]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSGAITFDEL KAGLRRYGST LKDTEIRDLM EAADVDNSGT IDYSEFIAAT IHLNKLEREE  60
   61 HLVSAFQYFD KDGSGYITID ELQQSCIEHG MTDVFLEDII KEVDQDNDGR IDYEEFVAMM 120
  121 QKGNAGVGRR TMKNSLNISM RDV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.69897
Match: 1s6iA
Description: Ca2+-regulatory region (CLD) from soybean calcium-dependent protein kinase-alpha (CDPK) in the presence of Ca2+ and the junction domain (JD)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.49668552859347 bayes_pls_golite062009
motor activity 3.25814691068414 bayes_pls_golite062009
binding 3.17556402087346 bayes_pls_golite062009
tubulin binding 2.51210014078446 bayes_pls_golite062009
actin binding 2.38676888633305 bayes_pls_golite062009
microtubule binding 2.17136406283012 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.51057181410195 bayes_pls_golite062009
kinase activity 1.48008348280256 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.34982153616582 bayes_pls_golite062009
metal ion binding 1.24254937475287 bayes_pls_golite062009
cation binding 1.24254937475287 bayes_pls_golite062009
ion binding 1.23493891392859 bayes_pls_golite062009
protein binding 1.16246005294206 bayes_pls_golite062009
calcium ion binding 1.03474411638676 bayes_pls_golite062009
transferase activity 1.00143834284844 bayes_pls_golite062009
structural constituent of muscle 0.99845401805886 bayes_pls_golite062009
actin filament binding 0.836375875773328 bayes_pls_golite062009
structural molecule activity 0.800850121197479 bayes_pls_golite062009
G-protein beta/gamma-subunit binding 0.77824189826064 bayes_pls_golite062009
transporter activity 0.594904129738596 bayes_pls_golite062009
transcription regulator activity 0.450279748770607 bayes_pls_golite062009
transmembrane transporter activity 0.346694954512987 bayes_pls_golite062009
nucleic acid binding 0.221865849692192 bayes_pls_golite062009
myosin binding 0.125186564742711 bayes_pls_golite062009
structural constituent of cytoskeleton 0.116648335890738 bayes_pls_golite062009
DNA binding 0.0960817636106102 bayes_pls_golite062009
microfilament motor activity 0.0834423172982799 bayes_pls_golite062009
substrate-specific transporter activity 0.0489908313324834 bayes_pls_golite062009

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