| Protein: | SMC4_ARATH |
| Organism: | Arabidopsis thaliana |
| Length: | 1241 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMC4_ARATH.
| Description | E-value | Query Range |
Subject Range |
|
|
329.0 | [0..6] | [980..194] |
|
Region A: Residues: [1-285] |
1 11 21 31 41 51
| | | | | |
1 MEEDEPMGGG ESEPEQRKSG TPRLYIKELV MRNFKSYAGE QRVGPFHKSF SAVVGPNGSG 60
61 KSNVIDAMLF VFGKRAKQMR LNKVSELIHN STNHQNLDSA GVSVQFEEII DLENGLYETV 120
121 PGSDFMITRV AFRDNSSKYY INERSSNFTE VTKKLKGKGV DLDNNRFLIL QGEVEQISLM 180
181 KPKAQGPHDE GFLEYLEDII GTNKYVEKID ELNKQLETLN ESRSGVVQMV KLAEKERDNL 240
241 EGLKDEAETY MLKELSHLKW QEKATKMAYE DTVAKITEQR DSLQN
|
| Detection Method: |  |
| Confidence: | 23.30103 |
| Match: | 1w1wA |
| Description: | Sc Smc1hd:Scc1-C complex, ATPgS |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleoside-triphosphatase activity | 2.69246499202248 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.61582393123755 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 2.59641929642359 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 2.59333672868803 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 2.58390156971125 | bayes_pls_golite062009 |
| binding | 2.4974940028864 | bayes_pls_golite062009 |
| transporter activity | 2.17383908004663 | bayes_pls_golite062009 |
| ATPase activity | 2.11122403732968 | bayes_pls_golite062009 |
| transmembrane transporter activity | 2.02444700826552 | bayes_pls_golite062009 |
| ATPase activity, coupled | 1.8908019270286 | bayes_pls_golite062009 |
| DNA helicase activity | 1.72320119360938 | bayes_pls_golite062009 |
| microtubule motor activity | 1.6537049553461 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 1.52935820732225 | bayes_pls_golite062009 |
| hydrolase activity | 1.35268825531078 | bayes_pls_golite062009 |
| motor activity | 1.34881124154297 | bayes_pls_golite062009 |
| helicase activity | 1.33212695797068 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.97700154207756 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 0.89390151223569 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 0.89390151223569 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.725611289205392 | bayes_pls_golite062009 |
| nucleotide binding | 0.717697610309727 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.713814218071151 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.713752628021599 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 0.654899784430321 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.608058786636536 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.579644950922817 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.500462538667228 | bayes_pls_golite062009 |
| catalytic activity | 0.458437698837681 | bayes_pls_golite062009 |
| protein binding | 0.378225828131122 | bayes_pls_golite062009 |
| centromeric DNA binding | 0.322818640526369 | bayes_pls_golite062009 |
| GTPase activity | 0.265618217985541 | bayes_pls_golite062009 |
| DNA clamp loader activity | 0.234068677215771 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.2192434828134 | bayes_pls_golite062009 |
| ATP binding | 0.19169045543599 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.165732470448462 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.162060759063149 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.114463153989353 | bayes_pls_golite062009 |
| microfilament motor activity | 0.10236059675512 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.081265446432119 | bayes_pls_golite062009 |
| recombinase activity | 0.0490751527151101 | bayes_pls_golite062009 |
| actin binding | 0.00482938540552702 | bayes_pls_golite062009 |
|
Region A: Residues: [286-557] |
1 11 21 31 41 51
| | | | | |
1 LENSLKDERV KMDESNEELK KFESVHEKHK KRQEVLDNEL RACKEKFKEF ERQDVKHRED 60
61 LKHVKQKIKK LEDKLEKDSS KIGDMTKESE DSSNLIPKLQ ENIPKLQKVL LDEEKKLEEI 120
121 KAIAKVETEG YRSELTKIRA ELEPWEKDLI VHRGKLDVAS SESELLSKKH EAALKAFTDA 180
181 QKQLSDISTR KKEKAAATTS WKADIKKKKQ EAIEARKVEE ESLKEQETLV PQEQAAREKV 240
241 AELKSAMNSE KSQNEVLKAV LRAKENNQIE GI
|
| Detection Method: | |
| Confidence: | 2.85 |
| Match: | 1c1gA |
| Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [558-767] |
1 11 21 31 41 51
| | | | | |
1 YGRMGDLGAI DAKYDVAIST ACAGLDYIVV ETTSSAQACV ELLRKGNLGF ATFMILEKQT 60
61 DHIHKLKEKV KTPEDVPRLF DLVRVKDERM KLAFYAALGN TVVAKDLDQA TRIAYGGNRE 120
121 FRRVVALDGA LFEKSGTMSG GGGKARGGRM GTSIRATGVS GEAVANAENE LSKIVDMLNN 180
181 IREKVGNAVR QYRAAENEVS GLEMELAKSQ
|
| Detection Method: | |
| Confidence: | 4.46 |
| Match: | 1gxlA |
| Description: | Smc hinge domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.7707163143035 | bayes_pls_golite062009 |
| protein binding | 1.2343536336523 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.56283355879326 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.511272811276509 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.299763949828861 | bayes_pls_golite062009 |
| DNA secondary structure binding | 0.284996962785104 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.248383422632029 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.235472660839816 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.233111707634177 | bayes_pls_golite062009 |
| protein dimerization activity | 0.210107708818734 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.155323194767055 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.101477244722795 | bayes_pls_golite062009 |
| ATPase activity | 0.08869715759545 | bayes_pls_golite062009 |
|
Region A: Residues: [768-1063] |
1 11 21 31 41 51
| | | | | |
1 REIESLNSEH NYLEKQLASL EAASQPKTDE IDRLKELKKI ISKEEKEIEN LEKGSKQLKD 60
61 KLQTNIENAG GEKLKGQKAK VEKIQTDIDK NNTEINRCNV QIETNQKLIK KLTKGIEEAT 120
121 REKERLEGEK ENLHVTFKDI TQKAFEIQET YKKTQQLIDE HKDVLTGAKS DYENLKKSVD 180
181 ELKASRVDAE FKVQDMKKKY NELEMREKGY KKKLNDLQIA FTKHMEQIQK DLVDPDKLQA 240
241 TLMDNNLNEA CDLKRALEMV ALLEAQLKEL NPNLDSIAEY RSKVELYNGR VDELNS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1064-1241] |
1 11 21 31 41 51
| | | | | |
1 VTQERDDTRK QYDELRKRRL DEFMAGFNTI SLKLKEMYQM ITLGGDAELE LVDSLDPFSE 60
61 GVVFSVRPPK KSWKNIANLS GGEKTLSSLA LVFALHHYKP TPLYVMDEID AALDFKNVSI 120
121 VGHYVKDRTK DAQFIIISLR NNMFELADRL VGIYKTDNCT KSITINPGSF AVCQKTPA
|
| Detection Method: | |
| Confidence: | 17.0 |
| Match: | 1xewY |
| Description: | Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases. |
Matching Structure (courtesy of the PDB): |
|
