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View Structure Prediction Details

Protein: gi|15220009, gi|...
Organism: Arabidopsis thaliana
Length: 476 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|15220009, gi|....

Description E-value Query
Range
Subject
Range
gi|76654204 - gi|76654204|ref|XP_584699.2| PREDICTED: similar to cytochrome P450, subfamily IIIA, polypeptide 4 is...
331.0 [0..2] [474..1]

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Predicted Domain #1
Region A:
Residues: [1-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEIITVRKV FLIGFLILIL NWVWRAVNWV WLRPKRLEKY LKKQGFSGNS YRILMGDMRE  60
   61 SNQMDQVAHS LPLPLDADFL PRMMPFLHHT VLKHGKKCFT WYGPYPNVIV MDPETLREIM 120
  121 SKHELFPKPK IGSHNHVFLS GLLNHEGPKW SKHRSILNPA FRIDNLKSIL PAFNSSCKEM 180
  181 LEEWERLASA KGTMELDSWT HCHDLTRNML ARASFGDSYK DGIKIFEIQQ EQIDLGLLAI 240
  241 RAVYIPGSKF LPTKFNRRLR ETERDMRAMF KAMIETKEEE IKRGRAGQNV TSSLFVWTLV 300
  301 ALSQHQDWQN KARDEISQAF GNNEPDFEGL SHLKVVTMIL HEVLRLYSPA YFTCRITKQE 360
  361 VKLERFSLPE GVVVTIPMLL VHHDSDLWGD DVKEFKPERF ANGVAGATKG RLSFLPFSSG 420
  421 PRTCIGQNFS MLQAKLFLAM VLQRFSVELS PSYTHAPFPA ATTFPQHGAH LIIRKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.69897
Match: 1tqnA
Description: Crystal Structure of Human Microsomal P450 3A4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
arachidonic acid monooxygenase activity 6.76823710927794 bayes_pls_golite062009
fatty acid (omega-1)-hydroxylase activity 6.3313834755701 bayes_pls_golite062009
arachidonic acid epoxygenase activity 4.80764258881036 bayes_pls_golite062009
monooxygenase activity 4.39701968168633 bayes_pls_golite062009
steroid hydroxylase activity 3.34643016685712 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3.24344797738248 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2.56821164444595 bayes_pls_golite062009
oxidoreductase activity 2.09151585300316 bayes_pls_golite062009
arachidonic acid 11,12-epoxygenase activity 2.0071742914584 bayes_pls_golite062009
retinoic acid 4-hydroxylase activity 1.90796041033974 bayes_pls_golite062009
oxygen binding 1.66120675703571 bayes_pls_golite062009
electron carrier activity 1.48516712188486 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.20113920678403 bayes_pls_golite062009
retinoid binding 1.16961058051431 bayes_pls_golite062009
oxysterol 7-alpha-hydroxylase activity 1.13877300596184 bayes_pls_golite062009
binding 1.0881336564542 bayes_pls_golite062009
demethylase activity 1.0502020132476 bayes_pls_golite062009
isoprenoid binding 1.04601505165702 bayes_pls_golite062009
ecdysteroid 25-hydroxylase activity 0.89030345144459 bayes_pls_golite062009
flavonoid 3'-monooxygenase activity 0.89030345144459 bayes_pls_golite062009
retinoic acid binding 0.851040588981921 bayes_pls_golite062009
catalytic activity 0.608111453189583 bayes_pls_golite062009
steroid 17-alpha-monooxygenase activity 0.56337818662492 bayes_pls_golite062009
sterol 14-demethylase activity 0.510328098559181 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 0.359684900320521 bayes_pls_golite062009

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