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View Structure Prediction Details

Protein: FK201_ARATH
Organism: Arabidopsis thaliana
Length: 190 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FK201_ARATH.

Description E-value Query
Range
Subject
Range
gi|22294826, gi|... - gi|22298646|ref|NP_681893.1| FKBP-type peptidyl-prolyl cis-trans isomerase [Thermosynechococcus elon...
156.0 [0..1] [121..46]

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Predicted Domain #1
Region A:
Residues: [1-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDAIDLSGD GGVLKKIVRS AKPDAISPSD DLPVVDVHYE GILAEDEKVF DTTREDNLVF  60
   61 SFELGTGSVI RSWDIALKTM KVGEVAKITC KPEYAYGRAG SPPDIPPDAT LIFEVELVAC 120
  121 RPRKGASVGS VSEERARLED LKKQREIAAA AKEDDKKKRE EAKAAAAARI QAKLDAKKGP 180
  181 GKGKGKGKAK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.69897
Match: 1q1cA
Description: Crystal structure of N(1-260) of human FKBP52
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
intracellular ligand-gated calcium channel activity 10.9968443145942 bayes_pls_golite062009
ryanodine-sensitive calcium-release channel activity 10.9968443145942 bayes_pls_golite062009
macrolide binding 7.31599503004442 bayes_pls_golite062009
FK506 binding 7.22442625476031 bayes_pls_golite062009
metal ion transmembrane transporter activity 6.74926751944787 bayes_pls_golite062009
calcium channel activity 6.4374377859142 bayes_pls_golite062009
cation channel activity 6.06732269872248 bayes_pls_golite062009
ion channel activity 5.45007096522107 bayes_pls_golite062009
passive transmembrane transporter activity 5.32426176964634 bayes_pls_golite062009
channel activity 5.32426176964634 bayes_pls_golite062009
substrate-specific channel activity 5.28960420749143 bayes_pls_golite062009
gated channel activity 5.28074654906904 bayes_pls_golite062009
peptidyl-prolyl cis-trans isomerase activity 4.0615867467963 bayes_pls_golite062009
cis-trans isomerase activity 3.99265212272703 bayes_pls_golite062009
ligand-gated channel activity 3.34717828007833 bayes_pls_golite062009
ligand-gated ion channel activity 3.34717828007833 bayes_pls_golite062009
ion transmembrane transporter activity 2.6566793500337 bayes_pls_golite062009
cation transmembrane transporter activity 2.61794461605199 bayes_pls_golite062009
calcium-release channel activity 2.58969194870156 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.47257819150887 bayes_pls_golite062009
isomerase activity 2.31710030777753 bayes_pls_golite062009
transcription regulator activity 1.712368250919 bayes_pls_golite062009
binding 1.63170667962375 bayes_pls_golite062009
molecular transducer activity 1.35482339720806 bayes_pls_golite062009
signal transducer activity 1.35482339720806 bayes_pls_golite062009
drug binding 1.28204013795445 bayes_pls_golite062009
transporter activity 1.25197125648774 bayes_pls_golite062009
transmembrane transporter activity 1.03909235910355 bayes_pls_golite062009
catalytic activity 0.885282592863018 bayes_pls_golite062009
receptor activity 0.857814413677739 bayes_pls_golite062009
substrate-specific transporter activity 0.789390402522536 bayes_pls_golite062009
intracellular ligand-gated ion channel activity 0.727019445105701 bayes_pls_golite062009
transmembrane receptor activity 0.725838740508674 bayes_pls_golite062009
kinase activity 0.672317708125682 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.655205651562943 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.575514956833065 bayes_pls_golite062009
protein kinase activity 0.377540111031875 bayes_pls_golite062009
transferase activity 0.33716295972018 bayes_pls_golite062009
unfolded protein binding 0.27473817613726 bayes_pls_golite062009
histone binding 0.221748741603068 bayes_pls_golite062009
transcription elongation regulator activity 0.21145105012677 bayes_pls_golite062009
protein binding 0.0371998661994551 bayes_pls_golite062009

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