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View Structure Prediction Details

Protein: CE31374
Organism: Caenorhabditis elegans
Length: 468 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE31374.

Description E-value Query
Range
Subject
Range
gi|39598266, gi|... - gi|39598266|emb|CAE68958.1| Hypothetical protein CBG14938 [Caenorhabditis briggsae], gi|187027572|em...
gi|157745495 - gi|157745495|ref|XP_001667844.1| Hypothetical protein CBG14938 [Caenorhabditis briggsae AF16]
404.0 [0..1] [468..1]

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Predicted Domain #1
Region A:
Residues: [1-408]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRLFETADT DRADFWHAPS VVNGTVDIMV APEHTDQFRQ YLEKHGYTFQ VAIDDLHKLL  60
   61 IEKEGNLSTH SNDDAFFLKR LHDDVGFHSR LRMGEYYSYS VLSTWLERIA ENMPDIAKLI 120
  121 KVGTTIEGRD ILGLKFGKDT PDKKIVVIDA GIHAREWAAI HTASYFINLI VNGREEDPQI 180
  181 QNYLDNIVLY IIPVLNPDGY EYTRTDKTNP RARMWRKSRS PKACAFDGVR NSCCMGVDLN 240
  241 RNFDFRFSEI GASRYPCSEI YHGPSAFSEP ESKAYSQFLT SLKGRLEAYI TLHSYSQLWI 300
  301 YSYSHRKFTY APDIEETRRV AAKAVQELGR MYGTKYRHGT GPEIIYAFSG GSTDWAKETL 360
  361 KIKYSYTIEL RPGYEEWNGF VLDKNQLIPT AKETWAGVTV VLDEVTNQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 97.154902
Match: 1ayeA
Description: HUMAN PROCARBOXYPEPTIDASE A2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.786910294594 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.40766568731738 bayes_pls_golite062009
hydrolase activity 4.23257784904124 bayes_pls_golite062009
exopeptidase activity 3.28577934113028 bayes_pls_golite062009
metallopeptidase activity 2.76103081380105 bayes_pls_golite062009
carboxypeptidase activity 2.63658263814587 bayes_pls_golite062009
metalloexopeptidase activity 1.76058821499096 bayes_pls_golite062009
metallocarboxypeptidase activity 1.56827526553175 bayes_pls_golite062009
catalytic activity 1.3989281287879 bayes_pls_golite062009
binding 1.13031326446259 bayes_pls_golite062009
endopeptidase activity 0.910234727191613 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 0.723243947871592 bayes_pls_golite062009
serine hydrolase activity 0.596149133958797 bayes_pls_golite062009
serine-type peptidase activity 0.578572340123331 bayes_pls_golite062009
nucleic acid binding 0.454707207494165 bayes_pls_golite062009
transcription regulator activity 0.273337363793137 bayes_pls_golite062009
DNA binding 0.115087846898245 bayes_pls_golite062009
aminopeptidase activity 0.0966237570696103 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [409-468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WKSSRVRESE LSRLRQEKCS DRLPGCAYWL QSSPNICRFS QSTMVRDCAK TCNLCHMIAV  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.69897
Match: 1h8lA
Description: Carboxypeptidase D, a regulatory domain; Carboxypeptidase D, catalytic domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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