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View Structure Prediction Details

Protein: wht-8
Organism: Caenorhabditis elegans
Length: 547 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for wht-8.

Description E-value Query
Range
Subject
Range
gi|56699519 - gi|56699519|gb|AAV97853.1| white [P-element transposon vector UASp]
w-PA - The gene white is referred to in FlyBase by the symbol Dmel\w (CG2759, FBgn0003996). It is a protein...
446.0 [0..1] [546..129]

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Predicted Domain #1
Region A:
Residues: [1-311]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGASGAGKTT LLNTLLQRNL RGLQVEGEIL VNGQNIGKGV TSVSAYVQQE DLFMGTLTVK  60
   61 EHLDIQAKLR LPPGTSTTAR ATRVNEVMNE MLLEKPRDSR IGVPGIKKGI SGGEMKRLAF 120
  121 ATEMINNPPI IFCDEPTTGL DSHMSLQVVK TLEQMALEKG KTIICTIHQP SSEVVFLAQG 180
  181 RIAFHGAIDE AIHHFSSCGY QVPDHTNPAD YFIDTLAIKP SEAEACKSRC QELCDKFEKS 240
  241 FYNERLTKLM DQTKDVRAMT PHHSATYPVL LYALFYRYML DNIRNPAIMK AKLIQKLFMG 300
  301 LFIGTLFYGL E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.69897
Match: 1v43A
Description: Crystal Structure of ATPase subunit of ABC Sugar Transporter
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
P-P-bond-hydrolysis-driven transmembrane transporter activity 6.58863529263644 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 6.58067278719409 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 6.57974651657836 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 6.57922174989907 bayes_pls_golite062009
primary active transmembrane transporter activity 6.57807080367604 bayes_pls_golite062009
nucleoside-triphosphatase activity 6.48406410175216 bayes_pls_golite062009
active transmembrane transporter activity 6.48154954364331 bayes_pls_golite062009
pyrophosphatase activity 6.40467109535527 bayes_pls_golite062009
ATPase activity, coupled 6.40151534181487 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 6.38373914253885 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 6.38247436082206 bayes_pls_golite062009
ATPase activity 6.30019941712404 bayes_pls_golite062009
hydrolase activity 5.13885856289543 bayes_pls_golite062009
sterol transporter activity 4.45355165759136 bayes_pls_golite062009
purine ribonucleotide binding 3.40690615950081 bayes_pls_golite062009
ribonucleotide binding 3.40594996232845 bayes_pls_golite062009
purine nucleotide binding 3.3669118613715 bayes_pls_golite062009
nucleotide binding 3.33248266870364 bayes_pls_golite062009
ATP binding 3.17398570826788 bayes_pls_golite062009
lipid transporter activity 3.14635082108971 bayes_pls_golite062009
adenyl ribonucleotide binding 3.12628113185041 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
adenyl nucleotide binding 3.0710107594224 bayes_pls_golite062009
drug transmembrane transporter activity 2.97119034312001 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
cholesterol transporter activity 2.72457626066894 bayes_pls_golite062009
binding 2.21604035604783 bayes_pls_golite062009
2.20174656498665 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
nucleic acid binding 1.62884148289979 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.56325751172863 bayes_pls_golite062009
DNA binding 1.53176391519962 bayes_pls_golite062009
transcription regulator activity 1.49517431175162 bayes_pls_golite062009
peptide-transporting ATPase activity 1.37783759788533 bayes_pls_golite062009
glycoprotein transporter activity 1.30536878174919 bayes_pls_golite062009
sterol-transporting ATPase activity 1.30536878174919 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
peptide transporter activity 1.19353064661766 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
ion transmembrane transporter activity 0.977237423302079 bayes_pls_golite062009
motor activity 0.87979065815418 bayes_pls_golite062009
GTPase activity 0.83849854735032 bayes_pls_golite062009
phospholipid transporter activity 0.755445322666929 bayes_pls_golite062009
guanyl nucleotide binding 0.640772201693186 bayes_pls_golite062009
guanyl ribonucleotide binding 0.63468044350616 bayes_pls_golite062009
GTP binding 0.621689261700018 bayes_pls_golite062009
cation transmembrane transporter activity 0.557919489256916 bayes_pls_golite062009
protein transporter activity 0.498432226280822 bayes_pls_golite062009
transcription factor activity 0.344643343870781 bayes_pls_golite062009
syntaxin-13 binding 0.310540417068989 bayes_pls_golite062009
apolipoprotein receptor activity 0.310540417068989 bayes_pls_golite062009
apolipoprotein A-I binding 0.310540417068989 bayes_pls_golite062009
apolipoprotein A-I receptor activity 0.310540417068989 bayes_pls_golite062009
molecular transducer activity 0.286367085584159 bayes_pls_golite062009
signal transducer activity 0.286367085584159 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 0.213018989352421 bayes_pls_golite062009
G-protein coupled receptor activity 0.169034229773346 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.123304946374679 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.0775601177068852 bayes_pls_golite062009
transcription activator activity 0.0291047953833683 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [312-547]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDQDGLASYK GALFYYISEL TYSTIFGIQA FMPADYPPLV REYDDRIYPI SAYYIAKICS  60
   61 FLPIFTVDGI ILVVSSYFLV GFPSDFGVFL RQIFTCMAIE WNVAALGIAV CATAPSYAIA 120
  121 VTVTGPLLTV FSLTGGLFTN IAEMPAWINW VQYLSWFRYG YESLVVNQFQ HDQFANITCN 180
  181 ANMNEQLCEK SGPIAIKNFS FDTANLYTNW VAMIYLTIII YIVGYMGLVR RVIANR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 14.638272
Match: PF01061.15
Description: No description for PF01061.15 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle