| Protein: | eat-16 |
| Organism: | Caenorhabditis elegans |
| Length: | 473 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for eat-16.
| Description | E-value | Query Range |
Subject Range |
|
|
438.0 | [0..2] | [429..261] |
|
Region A: Residues: [1-247] |
1 11 21 31 41 51
| | | | | |
1 MMPPLTKIEV LAKRVMEGAQ LKTHKYFRIA VPHAITGQQL IALVLERGAP DDEAEASHLA 60
61 SLLLHHGYMF PVIEHGQPFK DDGTLYRLQR PYFWPSQAEL VPDVEYAIYL NKRLLRNEQK 120
121 HGLEEDEVES FNRLADVLAH MWAFIVQQSE LQLKQQKEKK KVDKVVFDSE ERAFWKIRKP 180
181 SRGGPNFLED PYMKIEKKIR RQNAQGYRCL MDRLRFAIKT KPWLKALKAS DTMVTWVDQR 240
241 AEFDPFL
|
| Detection Method: |  |
| Confidence: | 24.39794 |
| Match: | 1o7fA |
| Description: | Regulatory domain of epac2, domain 2; Regulatory domain of Epac2, domains 1 and 3 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| substrate-specific channel activity | 3.81400803751315 | bayes_pls_golite062009 |
| gated channel activity | 3.75615867846417 | bayes_pls_golite062009 |
| ligand-gated channel activity | 3.71111882888041 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 3.71111882888041 | bayes_pls_golite062009 |
| cation channel activity | 3.61025292543387 | bayes_pls_golite062009 |
| ion channel activity | 3.49583875363169 | bayes_pls_golite062009 |
| channel activity | 3.47292007271524 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 3.47292007271524 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 2.28757379242869 | bayes_pls_golite062009 |
| binding | 2.23085040327125 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.09857147539905 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 1.83682117020899 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.73592246548483 | bayes_pls_golite062009 |
| intracellular ligand-gated ion channel activity | 1.68618484766279 | bayes_pls_golite062009 |
| protein kinase regulator activity | 1.51216484289697 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.4788427609721 | bayes_pls_golite062009 |
| molecular transducer activity | 1.29733029674587 | bayes_pls_golite062009 |
| signal transducer activity | 1.29733029674587 | bayes_pls_golite062009 |
| intracellular cyclic nucleotide activated cation channel activity | 1.26984296847489 | bayes_pls_golite062009 |
| cyclic nucleotide-gated ion channel activity | 1.26984296847489 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.817946345456311 | bayes_pls_golite062009 |
| protein binding | 0.81302068072988 | bayes_pls_golite062009 |
| transcription regulator activity | 0.788367835670939 | bayes_pls_golite062009 |
| transcription factor binding | 0.63938506997853 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.49916895549368 | bayes_pls_golite062009 |
| DNA binding | 0.49707830237564 | bayes_pls_golite062009 |
| nucleic acid binding | 0.470291687819709 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 0.46805096166885 | bayes_pls_golite062009 |
| voltage-gated channel activity | 0.46337812086906 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.238077419568415 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.235806909995514 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.215760255961604 | bayes_pls_golite062009 |
| transcription factor activity | 0.192522789488363 | bayes_pls_golite062009 |
| kinase regulator activity | 0.18055371101756 | bayes_pls_golite062009 |
| receptor binding | 0.0995086620605325 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 0.0560460005338929 | bayes_pls_golite062009 |
|
Region A: Residues: [248-473] |
1 11 21 31 41 51
| | | | | |
1 HPPQPSNPWI SDEASFWNQP TDTSSAEIPT EKRVKRWGLS VQELVKDPIG RQVLETFLES 60
61 EFSSENIRFW IAIQDLKYAP NEQIYQKAER IREEFLAQGA PAQVNVDNRT LDQTLECISK 120
121 AKDASQMRFA FYHSEEHVFT LMAKDSYPRF VRSQIYKAVL TAAQQHGTKR LGWRNFVFNM 180
181 GTTKKPATSK PAKPQDSIGT GQVLPKQLSS DSLPVRQAHG VKPDPE
|
| Detection Method: | |
| Confidence: | 36.0 |
| Match: | 1fqiA |
| Description: | RGS9, RGS domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.35238988967981 | bayes_pls_golite062009 |
| GTPase regulator activity | 1.92987277493861 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.90800479999702 | bayes_pls_golite062009 |
| GTPase activator activity | 1.87534424848905 | bayes_pls_golite062009 |
| enzyme activator activity | 1.62073651679221 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.49796137854909 | bayes_pls_golite062009 |
| protein binding | 1.34804002381061 | bayes_pls_golite062009 |
| signal transducer activity | 1.14361809679544 | bayes_pls_golite062009 |
| molecular transducer activity | 1.14361809679544 | bayes_pls_golite062009 |
| beta-catenin binding | 0.59248827140739 | bayes_pls_golite062009 |
