YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: mdh-1
Organism: Caenorhabditis elegans
Length: 341 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mdh-1.

Description E-value Query
Range		 Subject
Range
MDHM_FRAAN - Malate dehydrogenase, mitochondrial OS=Fragaria ananassa GN=MMDHI PE=1 SV=1
 291.0 [0..2] [341..1]

Back

Predicted Domain #1
Region A:
Residues: [1-341] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLPAKTLVQ AAANSGLRAV SVRHSSQAPK VALLGAAGGI GQPLGLLLKQ DPLVAHLALY  60
   61 DVVNTPGVAA DLSHIDSNAK VTAHTGPKEL YAAVENADVI VIPAGVPRKP GMTRDDLFNT 120
  121 NAGIVRDLAA VIAKASPKAL IAIITNPVNS TVPIASEVLK KAGVYDPKRV FGVTTLDVVR 180
  181 SQAFVSELKG HDASKTVVPV VGGHAGITII PLLSQVKPST KFSEEEISKL TPRIQDAGTE 240
  241 VVNAKAGAGS ATLSMALAGA RFANALVRGI KGEKNVQCAY VASDAVKGVE YFSTPVELGP 300
  301 NGVEKILGVG KVSAYEQKLI DASVPELNKN IAKGVAFVKG N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.522879
Match: 1mldA
Description: Malate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
malate dehydrogenase activity 7.69241456337154 bayes_pls_golite062009
L-malate dehydrogenase activity 5.35837481826138 bayes_pls_golite062009
lactate dehydrogenase activity 4.66418715735914 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 3.06391460989761 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 3.02758902218302 bayes_pls_golite062009
malic enzyme activity 2.98382582538724 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 2.94416173750168 bayes_pls_golite062009
oxidoreductase activity 2.75947908917144 bayes_pls_golite062009
L-lactate dehydrogenase activity 2.59062377380589 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 2.58076782195922 bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent 2.26153457113968 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.88605255677599 bayes_pls_golite062009
binding 1.76718756313666 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 1.70038641098437 bayes_pls_golite062009
catalytic activity 1.67029398049886 bayes_pls_golite062009
protein binding 1.47646217957458 bayes_pls_golite062009
retinol dehydrogenase activity 1.16811519855038 bayes_pls_golite062009
NAD or NADH binding 1.02662588361709 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.99118526697655 bayes_pls_golite062009
transporter activity 0.793769336118517 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.788034697021177 bayes_pls_golite062009
fatty acid synthase activity 0.714637370305282 bayes_pls_golite062009
transmembrane transporter activity 0.635891484075352 bayes_pls_golite062009
coenzyme binding 0.59785037604907 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.576163737662951 bayes_pls_golite062009
DNA binding 0.525227236870065 bayes_pls_golite062009
nucleic acid binding 0.459537641913493 bayes_pls_golite062009
enoyl-CoA hydratase activity 0.439912268968251 bayes_pls_golite062009
substrate-specific transporter activity 0.300373102236296 bayes_pls_golite062009
active transmembrane transporter activity 0.239024094835991 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 0.216422278300306 bayes_pls_golite062009
molecular transducer activity 0.201915860594054 bayes_pls_golite062009
signal transducer activity 0.201915860594054 bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity 0.192594057004213 bayes_pls_golite062009
transcription regulator activity 0.177044638410302 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.165260811069909 bayes_pls_golite062009
NADPH:quinone reductase activity 0.136079082491021 bayes_pls_golite062009
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity 0.120195861875768 bayes_pls_golite062009
ion transmembrane transporter activity 0.0257250793986203 bayes_pls_golite062009
glyoxylate reductase activity 0.0221984076575323 bayes_pls_golite062009
formate dehydrogenase activity 4.92199819939532E-4 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle