YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC4F6.17c
Organism:	Schizosaccharomyces pombe
Length:	803 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC4F6.17c.

Description	E-value	Query Range	Subject Range
gi\|25289923 - pir\|\|F98216 endopeptidase clp ATP-binding chain B [imported] - Agrobacterium tumefaciens (strain C58... gi\|15890799, gi\|... - gi\|15890799\|ref\|NP_356471.1\| hypothetical protein AGR_L_1346 [Agrobacterium tumefaciens str. C58], g...	562.0	[0..2]	[801..102]
gi\|115379537, gi... - gi\|115379537\|ref\|ZP_01466628.1\| AAA ATPase [Stigmatella aurantiaca DW4/3-1], gi\|115363446\|gb\|EAU6259...	560.0	[0..1]	[791..14]
gi\|25289928 - pir\|\|AF3276 ATP-dependent clp proteinase, ATP-binding chain clpb BMEI0195 [imported] - Brucella meli... gi\|17986479, gi\|... - gi\|17986479\|ref\|NP_539113.1\| ATP-dependent Clp protease, ATP-binding subunit CLPB [Brucella melitens...	559.0	[0..2]	[803..146]
CLPB_BRADU - Chaperone protein ClpB OS=Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 /... CLPB_BRAJA - Chaperone protein ClpB OS=Bradyrhizobium japonicum GN=clpB PE=3 SV=1	558.0	[0..4]	[801..92]
gi\|110635325, gi... - gi\|69280333\|ref\|ZP_00614948.1\| AAA ATPase, central region:Clp, N terminal [Mesorhizobium sp. BNC1], ...	557.0	[0..2]	[800..112]
gi\|77359882, gi\|... - gi\|77359882\|ref\|YP_339457.1\| ATP-dependent protease, Hsp 100, part of multi-chaperone system with Dn...	556.0	[0..1]	[790..88]
gi\|117929326, gi... - gi\|88931632\|ref\|ZP_01137326.1\| ATPase [Acidothermus cellulolyticus 11B], gi\|88912911\|gb\|EAR32347.1\| ...	556.0	[0..1]	[786..89]
CLPB_GLOVI - Chaperone protein ClpB OS=Gloeobacter violaceus GN=clpB PE=3 SV=1 CLPB_GLOVI - Chaperone protein ClpB OS=Gloeobacter violaceus (strain PCC 7421) GN=clpB PE=3 SV=1	556.0	[0..3]	[791..93]
gi\|67153835 - gi\|67153835\|ref\|ZP_00415580.1\| AAA ATPase, central region:Clp, N terminal [Azotobacter vinelandii Av... gi\|67087968, gi\|... - gi\|67153835\|ref\|ZP_00415580.1\| AAA ATPase, central region:Clp, N terminal [Azotobacter vinelandii Av...	555.0	[0..2]	[790..181]

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Predicted Domain #1

Region A:
Residues: [1-803]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNILPKSIPI RIQSLRRYQG SLKTSLRALS TRPIFEKRLL AETPFSIRPS NASVLIAKRS  60
   61 PKFGWKQVRF YAANPNGGNF RMDLGGGRKQ GAALEEYGTD LTALAKQGKL DPVIGREEEI 120
  121 QRTIQILSRR TKNNPALVGP AGVGKTAIME GLASRIIRGE VPESMKDKRV IVLDLGALIS 180
  181 GAKFRGDFEE RLKSVLSDLE GAEGKVILFV DEMHLLLGFG KAEGSIDASN LLKPALARGK 240
  241 LHCCGATTLE EYRKYIEKDA ALARRFQAVM VNEPSVADTI SILRGLKERY EVHHGVRITD 300
  301 DALVTAATYS ARYITDRFLP DKAIDLVDEA CSSLRLQQES KPDELRRLDR QIMTIQIELE 360
  361 SLRKETDTTS VERREKLESK LTDLKEEQDK LSAAWEEERK LLDSIKKAKT ELEQARIELE 420
  421 RTQREGNYAR ASELQYAIIP ELERSVPKEE KTLEEKKPSM VHDSVTSDDI AVVVSRATGI 480
  481 PTTNLMRGER DKLLNMEQTI GKKIIGQDEA LKAIADAVRL SRAGLQNTNR PLASFLFLGP 540
  541 TGVGKTALTK ALAEFLFDTD KAMIRFDMSE FQEKHTIARL IGSPPGYIGY EESGELTEAV 600
  601 RRKPYAVLLF DELEKAHHDI TNLLLQVLDE GFLTDSQGRK VDFRSTLIVM TSNLGSDILV 660
  661 ADPSTTVTPK SRDAVMDVVQ KYYPPEFLNR IDDQIVFNKL SEKNLEDIVN VRLDEVQQRL 720
  721 NDRRIILTVT EAARKWLAEK GYSPAYGARP LNRLIQKRIL NTMAMKIIQG EIKSDENVVI 780
  781 DVLDGELEFK ANKLEPQSTS HED

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	143.0
Match:	1qvrA
Description:	Crystal Structure Analysis of ClpB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	3.04833973586251	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	2.97325763395103	bayes_pls_golite062009
transmembrane transporter activity	2.88860382281825	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	2.82839518806942	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.62748401933955	bayes_pls_golite062009
pyrophosphatase activity	2.55282098898104	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.5316131833172	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.53035702378505	bayes_pls_golite062009
binding	2.21604035604783	bayes_pls_golite062009
hydrolase activity	2.18454736627863	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	2.11085913752215	bayes_pls_golite062009
ATPase activity	2.04651885449197	bayes_pls_golite062009
ATPase activity, coupled	1.87142752786895	bayes_pls_golite062009
substrate-specific transporter activity	1.61003954220885	bayes_pls_golite062009
nucleic acid binding	1.52921795164482	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.35976511031033	bayes_pls_golite062009
protein binding	1.22129154759482	bayes_pls_golite062009
DNA binding	1.19966224604123	bayes_pls_golite062009
transcription regulator activity	1.09075553688438	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
structural constituent of ribosome	0.738234102557832	bayes_pls_golite062009
motor activity	0.70874549510465	bayes_pls_golite062009
guanyl nucleotide binding	0.640772201693186	bayes_pls_golite062009
guanyl ribonucleotide binding	0.63468044350616	bayes_pls_golite062009
DNA-dependent ATPase activity	0.62832939629645	bayes_pls_golite062009
GTP binding	0.621689261700018	bayes_pls_golite062009
ion transmembrane transporter activity	0.613335848236039	bayes_pls_golite062009
GTPase activity	0.437665353870877	bayes_pls_golite062009
active transmembrane transporter activity	0.434775387083003	bayes_pls_golite062009
ATP binding	0.41092997612902	bayes_pls_golite062009
adenyl ribonucleotide binding	0.385813421701492	bayes_pls_golite062009
adenyl nucleotide binding	0.377870145186619	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.314819889840159	bayes_pls_golite062009
primary active transmembrane transporter activity	0.294474570607914	bayes_pls_golite062009
translation regulator activity	0.29096092258568	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.282352478532746	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.274994961137851	bayes_pls_golite062009
cation transmembrane transporter activity	0.226483101618176	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.220608508617331	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.219533217661421	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.219157471322311	bayes_pls_golite062009
transcription activator activity	0.129948034606198	bayes_pls_golite062009
transcription factor activity	0.0612932659603008	bayes_pls_golite062009
structural molecule activity	0.0558641287316701	bayes_pls_golite062009
structure-specific DNA binding	0.050232896280066	bayes_pls_golite062009
helicase activity	0.0450969969658499	bayes_pls_golite062009
protein transporter activity	0.0071389922757723	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: