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View Structure Prediction Details

Protein: rhp26
Organism: Schizosaccharomyces pombe
Length: 973 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rhp26.

Description E-value Query
Range
Subject
Range
gi|73999130 - gi|73999130|ref|XP_544097.2| PREDICTED: similar to chromodomain helicase DNA binding protein 7 isofo...
469.0 [0..3] [957..705]
CHD7_MOUSE - Chromodomain-helicase-DNA-binding protein 7 OS=Mus musculus GN=Chd7 PE=1 SV=1
468.0 [0..3] [957..696]
gi|109474645 - gi|109474645|ref|XP_232671.4| PREDICTED: similar to chromodomain helicase DNA binding protein 7 [Rat...
462.0 [0..3] [957..695]
gi|47215569 - gi|47215569|emb|CAG10740.1| unnamed protein product [Tetraodon nigroviridis]
462.0 [0..29] [957..41]
gi|114620586 - gi|114620586|ref|XP_519780.2| PREDICTED: chromodomain helicase DNA binding protein 7 [Pan troglodyte...
461.0 [0..3] [957..750]
CHD7_CHICK - Chromodomain-helicase-DNA-binding protein 7 OS=Gallus gallus GN=CHD7 PE=2 SV=1
460.0 [0..9] [957..717]
CHD7 - chromodomain helicase DNA binding protein 7
gi|225000838 - gi|225000838|gb|AAI72443.1| Chromodomain helicase DNA binding protein 7 [synthetic construct]
460.0 [0..3] [957..706]

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Predicted Domain #1
Region A:
Residues: [1-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVNEDLSHL GVFSVDQENL ERDVTNTASE YIAHESREIE KKRLQKVRKE ISSVKEKIRR  60
   61 LDERIDSRLT KISVKENFRK QLSKFRDTLQ SLQSDENDIK RRLNNEDSAN APGIGAFSTE 120
  121 ELERQELIRT GKVTPFRNLS GLQKEVDFDD ESSIREAVIK SEGTYYETAP HLSSEPSNID 180
  181 HGIIPRDEKD EYVTVDAVTE KVVTAAIDDG DDLVYRQRLN AWCANRKELR DQASASENNK 240
  241 DRGEFEGKDE WLLPHPSKK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.43
Match: 1jchA
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [260-823]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQTFEGGFTI PGDIRPHLFR YQVTCVQWLW ELYCQEAGGI IGDEMGLGKT IQIVSFLSSL  60
   61 HHSGKFQKPA LIVCPATLMK QWVNEFHTWW APLRVVVLHA TGSGQRASRE KRQYESDASE 120
  121 SEAEESKTSI KLRGASSSFH RYAKNLVESV FTRGHILITT YAGLRIYGDL ILPREWGYCV 180
  181 LDEGHKIRNP DSEISISCKQ IRTVNRIILS GTPIQNNLTE LWNLFDFVFP GRLGTLPVFQ 240
  241 NQFALPINIG GYANASNVQV QTAYKCACML RDLISPYLLR RMKLDVAADL PKKSEQVLFC 300
  301 KLTPLQRKAY QDFLQGSDMQ KILNGKRQML YGIDILRKIC NHPDLVTREY LLHKEDYNYG 360
  361 DPEKSGKLKV IRALLTLWKK QGHRTLLFSQ TRQMLDILEI GLKDLPDVHY CRMDGSTSIA 420
  421 LRQDLVDNFN KNEYFDVFLL TTRVGGLGVN LTGADRVILF DPDWNPSTDA QARERAWRLG 480
  481 QKKDVVVYRL MTAGTIEEKI YHRQIFKQFL TNKILKDPKQ RRFFKMTDLH DLFTLGDNKT 540
  541 EGTETGSMFL GSERVLRKDN SSRN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.0
Match: 1z3iX
Description: Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.64537357529343 bayes_pls_golite062009
nucleic acid binding 2.11222585187695 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.02893949194171 bayes_pls_golite062009
pyrophosphatase activity 1.97909493766908 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.95844964816653 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.95658009428828 bayes_pls_golite062009
DNA binding 1.7904783386531 bayes_pls_golite062009
transcription regulator activity 1.68903321260301 bayes_pls_golite062009
ATPase activity 1.42257610975945 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
DNA-dependent ATPase activity 1.2155186842031 bayes_pls_golite062009
helicase activity 1.16085745407703 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
hydrolase activity 0.98565595572967 bayes_pls_golite062009
ATPase activity, coupled 0.732723553251109 bayes_pls_golite062009
DNA helicase activity 0.72881469450553 bayes_pls_golite062009
purine nucleotide binding 0.725611289205392 bayes_pls_golite062009
structure-specific DNA binding 0.720649395550746 bayes_pls_golite062009
nucleotide binding 0.717697610309727 bayes_pls_golite062009
purine ribonucleotide binding 0.713814218071151 bayes_pls_golite062009
ribonucleotide binding 0.713752628021599 bayes_pls_golite062009
transcription factor activity 0.603758349693077 bayes_pls_golite062009
ATP-dependent helicase activity 0.59513742813869 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.59513742813869 bayes_pls_golite062009
double-stranded DNA binding 0.58862275163252 bayes_pls_golite062009
transcription activator activity 0.537911793669378 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
structural constituent of ribosome 0.396187998943318 bayes_pls_golite062009
microtubule motor activity 0.38363601832205 bayes_pls_golite062009
translation regulator activity 0.29096092258568 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.274994961137851 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.22150712609541 bayes_pls_golite062009
ATP binding 0.19169045543599 bayes_pls_golite062009
adenyl ribonucleotide binding 0.165732470448462 bayes_pls_golite062009
adenyl nucleotide binding 0.162060759063149 bayes_pls_golite062009
substrate-specific transporter activity 0.144154288308693 bayes_pls_golite062009
active transmembrane transporter activity 0.114463153989353 bayes_pls_golite062009
motor activity 0.0492172159259601 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [824-973]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNEAEDIPAR DRKKHKIHDK GKKVNSSKVF EKMGIASMEK YKPPQESNVT KTNSDSTLGD  60
   61 DSVLDDIFAS AGIQSTLKHD DIMEASQTES ILVEKEATRV ANEALRAVSS FRRPPRQLIP 120
  121 PQQSTNVPGT SKPSGPITSS TLLARLKQRR 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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