YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC9G1.13c
Organism:	Schizosaccharomyces pombe
Length:	411 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC9G1.13c.

Description	E-value	Query Range	Subject Range
gi\|114556092 - gi\|114556092\|ref\|XP_513103.2\| PREDICTED: DNA methyltransferase 1 associated protein 1 [Pan troglodyt...	440.0	[0..2]	[405..208]
gi\|7243231 - gi\|7243231\|dbj\|BAA92663.1\| KIAA1425 protein [Homo sapiens]	425.0	[0..2]	[405..31]
gi\|73978010 - gi\|73978010\|ref\|XP_532609.2\| PREDICTED: similar to DNMT1 associated protein-1 [Canis familiaris]	422.0	[0..2]	[405..36]
gi\|62649487, gi\|... - gi\|62649487\|ref\|XP_575894.1\| PREDICTED: similar to DNMT1 associated protein-1 [Rattus norvegicus], g...	416.0	[0..2]	[405..3]
gi\|115496444, gi... - gi\|94534765\|gb\|AAI16129.1\| DNA methyltransferase 1 associated protein 1 [Bos taurus], gi\|115496444\|r...	412.0	[0..2]	[400..3]
gi\|28856250, gi\|... - gi\|41053766\|ref\|NP_956549.1\| DNA methyltransferase 1 associated protein 1 [Danio rerio], gi\|28856250...	409.0	[0..2]	[406..3]
DMAP1_MOUSE - DNA methyltransferase 1-associated protein 1 OS=Mus musculus GN=Dmap1 PE=1 SV=1	404.0	[0..2]	[398..3]
gi\|89268692, gi\|... - gi\|89268692\|emb\|CAJ82704.1\| DNA methyltransferase 1 associated protein 1 [Xenopus tropicalis], gi\|53...	402.0	[0..2]	[404..3]

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Predicted Domain #1

Region A:
Residues: [1-170]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSADIRDVF ELPPPEIGNK QKSKTPTERR PEGISRELYS LLGENSAPLA IYQKKFKEKP  60
   61 KVSHKAKNWV RQPFSISSRK DDFTLHHWVL KSEVDSEAYE DWNKDETDYL FRLCKDYDLR 120
  121 FFVIADRYDN EKYKKHRTLE DLKDRFYSVS RKILLARNPI NSMTAAQSSL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.01
Match:	1a5jA
Description:	CHICKEN B-MYB DNA BINDING DOMAIN, REPEAT 2 AND REPEAT3, NMR, 32 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
lysine N-acetyltransferase activity	5.78270240334849	bayes_pls_golite062009
histone acetyltransferase activity	5.78270240334849	bayes_pls_golite062009
transcription regulator activity	4.86538715425734	bayes_pls_golite062009
N-acyltransferase activity	4.53404381270892	bayes_pls_golite062009
DNA binding	4.40186699787632	bayes_pls_golite062009
N-acetyltransferase activity	4.38345537045529	bayes_pls_golite062009
nucleic acid binding	4.28652307290136	bayes_pls_golite062009
acetyltransferase activity	3.81897719505269	bayes_pls_golite062009
transcription factor activity	3.78935192723648	bayes_pls_golite062009
acyltransferase activity	3.35931919126926	bayes_pls_golite062009
transcription repressor activity	3.3280771187468	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	3.31384699789032	bayes_pls_golite062009
transferase activity, transferring acyl groups	3.09869056563841	bayes_pls_golite062009
binding	2.92574888336072	bayes_pls_golite062009
sequence-specific DNA binding	2.15328641013602	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.00875399167309	bayes_pls_golite062009
transcription activator activity	1.5973137667873	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	1.5871271401402	bayes_pls_golite062009
transcription corepressor activity	1.30723796612579	bayes_pls_golite062009
transcription factor binding	1.24678737091956	bayes_pls_golite062009
protein deacetylase activity	1.23476914879396	bayes_pls_golite062009
histone deacetylase activity	1.18710646783152	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.865913662624162	bayes_pls_golite062009
chromatin binding	0.82130998265632	bayes_pls_golite062009
protein binding	0.795494287543952	bayes_pls_golite062009
transcription cofactor activity	0.691780246385357	bayes_pls_golite062009
DNA-dependent ATPase activity	0.658518317984762	bayes_pls_golite062009
structure-specific DNA binding	0.559482273209868	bayes_pls_golite062009
deacetylase activity	0.534082291544628	bayes_pls_golite062009
histone binding	0.489784140732052	bayes_pls_golite062009
cytoskeletal protein binding	0.244471307852075	bayes_pls_golite062009
telomeric DNA binding	0.233668696331578	bayes_pls_golite062009
transcription coactivator activity	0.201150053959035	bayes_pls_golite062009
DNA helicase activity	0.192832786095412	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.151335943405565	bayes_pls_golite062009
double-stranded DNA binding	0.0110175210304684	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [171-233]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNTMEYNKEQ EVIRKKYLIG LASRTPEEVA EEEALFIELK RIETSQAKLL SDRDEVLRLL  60
   61 DEQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [234-315]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGDGGIHEYH TSAGMSSLIQ DMINSQRTKN KVEEAIVSSS APSSGVSSVL NTPTRPHALS  60
   61 TPRIRYGPQP TDPQFGITWH EK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [316-411]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LHPGTFVRSQ KIPAIKASLS QRVSSVMTEL GVSSRLIMPT AKNFEKFVEL QNSIVSLLEL  60
   61 KRKVDRLSQE TEIQDKLSRK RSASPDGSES KKHISQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: