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View Structure Prediction Details

Protein: SPAC1F5.06
Organism: Schizosaccharomyces pombe
Length: 848 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC1F5.06.

Description E-value Query
Range		 Subject
Range
gi|483005, gi|188492 - pir||B45871 dnaK-type molecular chaperone HSP70-Hom - human, gi|188492|gb|AAA63228.1| heat shock-in...
 561.0 [0..19] [673..3]
HS71L_MACFA - Heat shock 70 kDa protein 1-like OS=Macaca fascicularis GN=HSPA1L PE=2 SV=1
gi|109070526, gi... - gi|109070526|ref|XP_001113356.1| PREDICTED: similar to heat shock 70kDa protein 1-like isoform 3 [Ma...
 559.0 [0..19] [673..3]
gi|25009896 - gi|25009896|gb|AAN71116.1| AT28834p [Drosophila melanogaster]
 559.0 [0..23] [675..44]
gi|67969126 - gi|67969126|dbj|BAE00917.1| unnamed protein product [Macaca fascicularis]
 559.0 [0..19] [673..3]
gi|114606521, gi... - gi|114606521|ref|XP_001160137.1| PREDICTED: heat shock 70kDa protein 1-like isoform 1 [Pan troglodyt...
 559.0 [0..19] [673..3]
gi|60654385 - gi|60654385|gb|AAX29883.1| heat shock 70kDa protein 1-like [synthetic construct]
 556.0 [0..19] [673..3]

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Predicted Domain #1
Region A:
Residues: [1-621] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRSVLTIIL FFSCQFWHAF ASSVLAIDYG TEWTKAALIK PGIPLEIVLT KDTRRKEQSA  60
   61 VAFKGNERIF GVDASNLATR FPAHSIRNVK ELLDTAGLES VLVQKYQSSY PAIQLVENEE 120
  121 TTSGISFVIS DEENYSLEEI IAMTMEHYIS LAEEMAHEKI TDLVLTVPPH FNELQRSILL 180
  181 EAARILNKHV LALIDDNVAV AIEYSLSRSF STDPTYNIIY DSGSGSTSAT VISFDTVEGS 240
  241 SLGKKQNITR IRALASGFTL KLSGNEINRK LIGFMKNSFY QKHGIDLSHN HRALARLEKE 300
  301 ALRVKHILSA NSEAIASIEE LADGIDFRLK ITRSVLESLC KDMEDAAVEP INKALKKANL 360
  361 TFSEINSIIL FGGASRIPFI QSTLADYVSS DKISKNVNAD EASVKGAAFY GASLTKSFRV 420
  421 KPLIVQDIIN YPYLLSLGTS EYIVALPDST PYGMQHNVTI HNVSTIGKHP SFPLSNNGEL 480
  481 IGEFTLSNIT DVEKVCACSN KNIQISFSSD RTKGILVPLS AIMTCEHGEL SSKHKLGDRV 540
  541 KSLFGSHDES GLRNNESYPI GFTYKKYGEM SDNALRLASA KLERRLQIDK SKAAHDNALN 600
  601 ELETLLYRAQ AMVDDDEFLE F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 150.0
Match: 1yuwA
Description: crystal structure of bovine hsc70(aa1-554)E213A/D214A mutant
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
unfolded protein binding 4.93074236328581 bayes_pls_golite062009
binding 2.11855816699924 bayes_pls_golite062009
carbohydrate kinase activity 1.95648644394423 bayes_pls_golite062009
cytoskeletal protein binding 1.69431775343358 bayes_pls_golite062009
structural constituent of cytoskeleton 1.43110879934367 bayes_pls_golite062009
peptidase activity 1.4127499531612 bayes_pls_golite062009
transporter activity 1.2883466875237 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.16749728168925 bayes_pls_golite062009
structural molecule activity 1.15845050752717 bayes_pls_golite062009
kinase activity 1.11102445353265 bayes_pls_golite062009
hexokinase activity 1.02961928132432 bayes_pls_golite062009
protein binding 0.956664772028256 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.953663805249074 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.900931843471417 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.898645342556399 bayes_pls_golite062009
pyrophosphatase activity 0.875671218597808 bayes_pls_golite062009
hydrolase activity 0.807017237368431 bayes_pls_golite062009
substrate-specific transporter activity 0.796517590178929 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.78242344952806 bayes_pls_golite062009
protein transporter activity 0.780308299678282 bayes_pls_golite062009
ATPase activity 0.687771333492666 bayes_pls_golite062009
myosin binding 0.607451856096 bayes_pls_golite062009
transcription regulator activity 0.309839091488096 bayes_pls_golite062009
catalytic activity 0.296484721581333 bayes_pls_golite062009
nucleic acid binding 0.227575032167565 bayes_pls_golite062009
protease binding 0.121259015422625 bayes_pls_golite062009
DNA binding 0.0569764181525874 bayes_pls_golite062009
chaperone binding 0.00111313452804307 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [622-848] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANPEETKILK NDSVESYDWL IEYGSQSPTS EVTDRYKKLD DTLKSISFRF DQAKQFNTSL  60
   61 ENFKNALERA ESLLTNFDVP DYPLNVYDEK DVKRVNSLRG TSYKKLGNQY YNDTQWLKDN 120
  121 LDSHLSHTLS EDPLIKVEEL EEKAKRLQEL TYEYLRRSLQ QPKLKAKKGA SSSSTAESKV 180
  181 EDETFTNDIE PTTALNSTST QETEKSRASV TQRPSSLQQE IDDSDEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle